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Chapter 2
An Integrative
Approach to
Psychopathology
Amber Gilewski
Tompkins Cortland Community College
One-Dimensional vs.
Multidimensional Models
One-Dimensional Models
Explain behavior in terms of a single cause
Could mean a paradigm, school, or
conceptual approach
Tendency to ignore information from other
areas
One-Dimensional vs.
Multidimensional Models
Multidimensional Models
Interdisciplinary, eclectic, and integrative
“System” of influences that cause and
maintain suffering
Draws upon information from several
sources
Genetic Contributions to
Psychopathology
Nature of Genes
Genes do not dictate behavioral outcomes
Genes create a predisposition or likelihood
Development and behavior is often polygenic
Interaction between genetic factors &
environment (i.e. nature and nurture)
New developments in study of genes/behavior
Less than 50% is genetic contribution
The Interaction of Genetic &
Environmental Effects
The Diathesis-Stress Model
Examples: blood-injury-injection phobia, alcoholism
Reciprocal Gene-Environment Model
Examples: Depression, sensation-seeking
Non-Genomic Inheritance of Behavior
Genes are not the whole story
Environmental influences may override genetics
Neuroscience Contributions
to Psychopathology
The Field of Neuroscience
The role of the nervous system in disease
and behavior
The Central Nervous System (CNS)
Brain and spinal cord
-processes information received from sense
organs
Neurons
The Neuron
Soma – Cell body
Dendrites – Branches that receive messages
from other neurons
Axon – Trunk of neuron that sends messages to
other neurons
Axon terminals (terminal buttons)– Buds at end
of axon from which chemical messages are sent
Synapses – Small gaps that separate neurons
The Structure
of the Brain
Two Main Parts
Brainstem - automatic functions
Forebrain – more advanced systems
Main Divisions
Hindbrain – medulla, pons, cerebellum
Midbrain – reticular activating system
Diencephalon – transmits info to forebrain
Teleencephalon – base of forebrain, limbic
system
The Structure
of the Brain
Hindbrain
Medulla – Heart rate, blood pressure, respiration
Pons – Regulates sleep stages
Cerebellum – Involved in physical coordination
Midbrain
Coordinates movement with sensory input
Contains parts of the reticular activating system
(RAS)
The Structure of the Brain
Forebrain (Cerebral Cortex)
Most sensory, emotional, and cognitive
processing
2 specialized hemispheres – left & right
Major Structures of the Brain
Fig. 2.6b2, p. 47
The 4 Lobes
Lobes of Cerebral Cortex
Frontal – Thinking and reasoning abilities,
memory
Parietal – Touch recognition
Occipital – Integrates visual input
Temporal – Recognition of sights and sounds,
long-term memory storage
Neurotransmitters &
The Brain
Brain circuits – pathways of neurotransmitters
Drug therapies – increase or decrease flow of
neurotransmitters
Agonists - mimic neurotransmitters
Antagonists - act against/block neurotransmitters
Inverse agonists -like agonists, but opposite effect
Most drugs are either agonistic or antagonistic
Main Types of
Neurotransmitters
Serotonin (5HT) – affects mood, behavior,
thought processes
Gamma aminobutyric acid (GABA) –
inhibits behavior and emotions, esp. anxiety
Norepinephrine – endocrine system,
contributes to mood and arousal
Dopamine – controls voluntary movements,
related to schizophrenia & Parkinson’s
Manipulating Serotonin in the Brain
Fig. 2.11, p. 52
Mental Illness in Social Context
How does the context of the situation
influence our interpretations about
mental illness?
What does this story say about the
stigma of mental illness?
What does it say about the potential
dangers of one-dimensional models?
Can you come up with other behaviors
that would have been misinterpreted in
this situation?