Transcript Time: 14.00 - 16.00 @ Room AZ-19, BME-TAM Bldg, BU

BME-LIFESCI-INOVITA-ISEK JOINT SEMINAR
(2014-SPR-10)
27 May (Tue)
Time: 14.00 - 16.00
@ Room AZ-19,
BME-TAM Bldg, B.U. Kandilli Campus
Pyramidal Neuron Function:
Computational Models &
in vitro Neurodegeneration
Pınar ÖZ
Guest Researcher/Instructor, Bogazici University BME
Pyramidal neurons are the most common type of excitatory cells in neortical
regions and hippocampus. The ability to modulate pyramidal neuron function in
response to behavioral state or as a long-term response to prior activation as a
mechanism of learning emphasize their crucial role in the proper functioning of
the brain. Their abundance in cortical regions also suggest that their proper
function is essential for cognitive processes and their dysfunction might lead to
cognitive impairents, associated with disorders like Alzheimer’s Disease and
schizophrenia. Therefore, it’s crucial to understand their function as a single
cell to understand the network response properties of cortex and hippocampus.
This talk will focus on (1) action potential generation in cortical pyramidal
neurons and how to simulate them, and (2) hippocampal pyramidal neuron
morphology and function in neurodegenerative diseases and how to design in
vitro models of pyramidal neuron degeneration.
Biography
BS (2002-2006), Department of Molecular Biology and Genetics, Bogazici University,
Istanbul, Turkey; MSc (2006-2007), International Max Planck Research School for
Neurosciences, Göttingen, Germany; PhD (2007-2011), International Max Planck Research
School for Neurosciences, Max Planck Institute for Dynamics and Self-Organization and
University Medicine, Göttingen, Germany); Post-doctoral Research (2011-2012), Theoretical
Neurophysics Group, Max Planck Institute for Dynamics and Self-Organization, Göttingen,
Germany, (2012-current), Cellular Imaging and Electrophysiology Lab, Institute of
Biomedical Engineering, Bogazici University, Istanbul, Turkey.
For seminar info; to receive electronic notices; for suggestions please contact: Dr. Cengizhan Ozturk, [email protected]