Transcript Chapter Two

Chapter 2
Biological Foundations of Behavior
1
Module 2.1
Neurons: The Body’s Wiring
Its EVOLUTION!
2
What is our advantage?

What puts us at a major advantage over other
animals which puts us at the top of the food
chain?
3
Our Brain!
4
It’s Evolution Baby!

The human brain is a product of generations of
adaptive mutations and adaptations.

Homo sapiens-100,000 years old (is this old?)
What the heck is natural selection?
5
The original Chuck D: Charles
Darwin
Evolve: To develop gradually.
 Gradual change in the structure of an animal or
plant as a result of natural selection.
 NS= process by which inherited traits that lead
to a selective advantage increase the likelihood
of reproduction.

6
The Adaptive Human

Brain size correlates with
intelligence? T or F

Bigger brain=Smarter?
7
Cephalisation Index

Ratio of brain weight to body weight.
K=E/P
K=Cephalisation Index
E=Brain weight in grams
P=Body weight in kilograms
Real Smart: Humans: .89
Dolphins: .64
Chimp:.30
Real Dumb: Sheep: .10
Rabbit: .05
8
Neurons!

The basic building block of the nervous
system
– Cells
– Transmit information via an electro-chemical
process.
9
Chapter 2
Biological Foundations of Behavior
10
Figure 2.1: The Neuron
soma
11
Cells in the Nervous System

Three types of neurons
– Sensory neurons (or “afferent neurons”)
– Motor neurons (or “efferent neurons”)
– Interneurons (or “associative neurons”)

Glial cells (the glue!)
– Account for 90% of cells in adult human brain
– Help hold neurons together
– Provide supports for the nervous system
12
Cells in the Nervous System

Sensory Neurons:
– Afferent nerves
– Information about the outside world to the
brain.
– Sensory organs to brain.
– 5 senses
– “That stinks!”
13
Cells in the Nervous System

Motor Neurons
– Efferent Nerves
– Sends message from the brain to the muscles
and glands to cause response/behavior or to
regulate bodily processes.
14
Cells in the Nervous System

Interneuron
– Most common neuron in the NS
– Connect neurons to neurons
– Connect sensory to motor, motor to sensory
– More on this later……I promise
15
How do they talk?

Electro-Chemical process
– Sodium (Na+) and Potassium (K+)
– A cell at rest – 70 (mV).
– Cell begins to let positive ions into the cell,
changing the polarity to + (40 mV)
– This is an action potential (firing or ‘spiking’)
– All-or-none Principle:
 Must have a full voltage of + 40 mv to fire.
 Won’t half fire or semi fire.
16
Action Potentials
17
What’s next?

Neurotransmission!
– When the neuron fires, the axon’s terminal
buttons release molecules of NT’s into
synaptic gap.
– They bind to Receptor sites on the dendrites
of other neurons.
– 2 possible outcomes:
 Excitatory
 Inhibitory
18
Module 2.2
The Nervous System:
Your Body’s Information Superhighway
19
Figure 2.4: Parts of the Nervous
System
20
Concept Chart 2.2:
Organization of the Nervous
System
The Nervous System
Central
Nervous System
Spinal Chord
Peripheral
Nervous System
Brain
Somatic
Nervous System
Autonomic
Nervous System
Sympathetic
Nervous System
Parasympathetic
Nervous System
21
Spinal Cord

Column of nerves extending from brain
– Protected by the spine
– Transmits information between the brain and
the peripheral nervous system

Controls some spinal reflexes
– Allows quick responses to particular types of
stimuli (evolution)

CNS regulates everything in the body.
22
Figure 2.5a: The Knee-Jerk
Reflex
afferent
efferent
23
Figure 2.5b: The Withdrawal
Reflex
24
Peripheral Nervous System
Connects the CNS with other body parts
 Divided into 2 parts:

– Somatic Nervous System: Transmits messages
between CNS and the sensory organs, glands,
and muscles (moves ya around)
– Autonomic Nervous System (ANS): Controls
internal bodily processes
– BP, Heart Rate, Etc…not aware but may be
affected by conscious things (stress, anger)
25
Divisions of the ANS

Sympathetic Nervous System
– Speeds up bodily processes
– Draws energy from stored reserves
– Activation often accompanied by strong emotions

Parasympathetic Nervous System
– Fosters bodily processes that replenish energy stores
– Helps conserve energy by slowing down other bodily
processes
26
Module 2.3
The Brain: Your Crowning Glory
27
Brain Facts




Average number of neurons in the brain = 100 billion
The average brain weighs about 3 pounds.
77% of a human brain is dedicated to the cerebral cortex.
31% is dedicated to a rat’s.
28
29
Hindbrain
Kickin’ it old school!
Lowest, oldest part of the brain
 Includes the:

– Medulla (heart beat etc.)
– Pons (time for bed…wake up!)
– Cerebellum (don’t trip… don’t forget to breathe)
30
Figure 2.6: The Brainstem
31
Midbrain
Contains nerve pathways that connect the
hindbrain with the forebrain
 Midbrain structures perform important roles

– e.g., control of automatic movements of the eye
muscles

Reticular formation plays key role in regulating
states of attention, alertness, and arousal.
32
Major Structures of the
Forebrain

Thalamus
– Relays sensory information to appropriate
parts of the cerebral cortex
– Receives input from the basal ganglia

Hypothalamus
– Regulates many vital bodily functions as well
as emotional states, aggressive behavior, and
response to stress
– (The 3 F’s)
33
The Limbic System

Group of interconnected structures:
– Amygdala: Helps regulate states of emotional
arousal
– Hippocampus: Plays important role in the
formation of memories
– Why can’t you remember when you were
born?
– Parts of the thalamus
– Parts of the hypothalamus
34
The Cerebral Cortex
Thin, outer layer of the largest part of the
forebrain which is called the cerebrum
 Cerebrum consists of the right and left
cerebral hemispheres.

– Hemispheres connected by the corpus
callosum
35
Figure 2.7: The Size of the
Cerebral Cortex in Humans and
Other Animals
36
Figure 2.8: Lobes of the Cerebral
Cortex
37
Table 2.1: The Lobes of the
Cerebral Cortex
38
Figure 2.9: Somatosensory Cortex
and Motor Cortex
39
Module 2.4
Methods of Studying the Brain
40
Methodology
Postmortem studies
 Animal Studies
 Electrical Recordings
 Static Imaging Techniques
 Metabolic Imaging

41
Recording and Imaging
Techniques
EEG (electroencephalograph)
 CT (computed tomography) scan
 PET (positron emission tomography) scan
 MRI (magnetic resonance imaging)
 fMRI (functional MRI)

42
Experimental Methods
Lesioning
 Electrical recording
 Electrical stimulation

43
Static: Magnetic Resonance
Imaging
• Strong magnetic field passed through the skull
• Uses the detection of radio frequency signals
produced by displaced radio waves in a
magnetic field
• Creates a detailed anatomical image of the
brain
44
45
Metabolic: Positron Emission
Tomography (PET)
Radioactive material is injected or inhaled
 Participant is then scanned to produce an
image of the brain’s activity

46
47
Metabolic: fMRI
fMRI imaging takes a series of images of the
brain in quick succession and then statistically
analyzes the images for differences among
them
 Brain areas with more blood flow have been
shown to have better visibility on fMRI images
BOLD
 Better visibility is correlated with brain
activation

48
What might this person be doing?
49
Module 2.5
The Divided Brain:
Specialization of Function
50
Lateralization of Brain Functions

Refers to division of functions between
right and left hemispheres
– Left hemisphere dominant for language
abilities, logical reasoning, and problem
solving
– Right hemisphere dominant in nonverbal
processing

People are not “left-brained” or “rightbrained.”
51
Figure 2.15: Broca’s and
Wernicke’s Area
Production
Comprehension
52
Broca’s and Wernicke’s Area

Broca’s Aphasia:
– Me: How are you today?
– BA: Ah ah ah ah ah ah ga ga ga ga ga ga ga
ga gmmmmmmmpppfffffffffff…good thanks

Wernicke’s Aphasia:
– Me: How are you today?
– WA: Kangaroos can box you know!
53
Split-Brain Research
Severing corpus callosum as treatment for
severe epilepsy
 Split-brain patients retain intellect and
personality
 But differences in perception, language
evident in special testing circumstances

54
Brain Damage and
Psychological Functioning
Case of Phineas Gage: Prefrontal cortex
damage
 Plasticity: Ability of the brain to adapt and
reorganize itself following trauma or
surgical alteration

55
What happened to Gage?

“indulging at times in the grossest profanity
(which was not previously his custom),
manifesting but little deference for his fellows,
impatient of restraint or advice when it conflicts
with his desires “


CONCLUSION?
Gage's case is cited as among the first evidence
suggesting that damage to the frontal lobes
could alter aspects of personality and affect
socially appropriate interaction
56
Module 2.7
Genes and Behavior:
A Case of Nature and Nurture
57
Genetic Influences on Behavior
Nature-nurture problem
 Genotype: An organism’s genetic code
 Phenotype: The observable physical and
behavioral characteristics of the organism
 Genetic and environmental influences
interact in complex ways to shape our
personality.

58
Kinship Studies
Familial association studies
 Twin studies

– Identical (MZ) vs. fraternal (DZ) twins
– Concordance rates

Adoptee studies
Continue
59
Figure 2.19: Genetic Overlap
Among Family Members
60