Neurons Signal Other Cells Across Synapses

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Transcript Neurons Signal Other Cells Across Synapses

Neurons Signal Other
Cells Across Synapses
Neurons Signal Other
Cells Across Synapses

Synapse is a
junction between
two neurons
Neurons Signal Other
Cells Across Synapses

Synapse is a
junction between a
neuron and a
muscle cell
Neurons Signal Other
Cells Across Synapses

Synapse is a
junction between a
neuron and an
endocrine gland
Neurons Signal Other
Cells Across Synapses

How does this work???
I’ll bet he had A
LOT of synapses!!
Chemical Synapses

action potential
reaches the end of
the axon
 Action
potential
CANNOT
“jump” the
gap
Chemical Synapses
electrical
signal
must be
converted
to a
chemical
one
Chemical Synapses
electrical
signal must
be
converted
to a
chemical
one
Chemical Synapses via.

Chemical messengers used by neurons
to signal other: neurons, muscles, or
endocrine glands
a neurotransmitter is
sent out and a dendrite
is stimulated
QuickTime™ and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
a neurotransmitter
is sent out and a
dendrite is stimulated
neurotransmitters
 acetylcholine
- neurotransmitter
that triggers muscle
contractions
neurotransmitters

serotonin neurotransmitter
that affects mood
neurotransmitters

endorphins neurotransmitter
that affects pain
regulation
Neurotransmitters bind
with receptors on
postsynaptic cells

Stored in
synaptic
vesicles
Neurotransmitters bind
with receptors on
postsynaptic cells
 action
potential
reaches
synaptic
terminal,
Ca+
channels
open
Neurotransmitters bind
with receptors on
postsynaptic cells
 Ca+
causes
vesicles to fuse
with the
presynaptic
membrane and
release the
neurotrnamitter
Neurotransmitters bind
with receptors on
postsynaptic cells
 Via:
exocytosis
Neurotransmitters bind
with receptors on
postsynaptic cells
 Neurotransmitters
combine with
receptor proteins
of the postsynaptic
neuron’s dendrites
Neurotransmitters bind
with receptors on
postsynaptic cells
 Sodium
gated ion
channels open…
Neurotransmitters bind
with receptors on
postsynaptic cells
 degraded
neurotransmittor is
reabsorbed into
presynaptic
neuron
And it begins again…