Transcript Temporal Enhancement of Motor Control in Parkinson’s

Temporal Enhancement of Motor
Control in Parkinson’s Disease
patients
Marta Bieńkiewicz
PhD Student
Queen’s University Belfast
Temporal
Enhancement
Temporal controlof
of the
movement
Motor
 Difficulties with timing the
Performance
movement in Parkinson’s Disease
Using
 Using cues to stimulate
Sensory
perception action coupling
Guides
Clinical symptoms of idiopathic
Parkinson’s Disease
• Four major motor dysfunctions:
bradykinesia
 bradykinesia
 rigidity
 tremor at rest
 postural instability
1 /500 in UK
Every year 10,000 are
diagnosed
(www.parkinsons.org.uk)
Progressive neurodegeneration
Anatomically
Parkinson’s Disease
exhibits a progressive
degeneration of the
substantia nigra cells
that are
interconnected with
dopaminergic neurons
in the striatum part of
the basal ganglia.
Paradoxical kinesia
Perception and
action coupling
Asmus et al. (2008). Kick and rush: Paradoxical kinesia in Parkinson
disease.Neurology.2008; 71: 695
Action
PARADOXICAL
KINESIA
Perceptual information available
none
intermittent
continuous
Temporal control
intrinsic
intrinsic/extrinsic
extrinsic
Pilot – Parkinson’s Disease
Self-paced
Moving ball
Pilot – Parkinson’s Disease
Self-paced
No vision – moving ball
HEIGHT OF THE RAMP
Research questions
• 1.) How PDs and healthy adults differ in
temporal control of the movement under
different spatial, temporal and informational
constraints?
• 2.) Can paradoxical kinesia be explained by
coupling the movement to the sensory
information available?
Goals
 Aritifical Sesory Guides in PD.
 Goal-directed actions.
 Effectiveness of cueing methods.
Focus
1.) Upper limb movements
2.) Turning
3.) Freezing
TEMPUS
G
Thank you for your
attention!
Special thanks to:
Dr Cathy Craig
Dr David Craig
Will Young
[email protected]