Transcript Slide 1
Chapter 1, HIV None Chapter 2, Pattern of Evolution What are vestigial traits and why are they present at all Chapter 3, Darwin and Natural Selection Does artificial selection represent new allele or just an allele in higher frequency? Need to explain how you go beyond limits of range of phenotypic variation found in population before selection (cross of Kale and cabbage) Chapter 4, Estimating Evolutionary Trees Define Homoplasy and Homology, and demonstrate how to use parsimony to distinguish the two Discuss the difference between monophyletic and polyphyletic Know the concepts of parsimony and cladistics What are SINE and LINE mutations and why are they useful in phylogenetic reconstruction (short and long interspersed elements) vs changes at base level (only 4 character states, thus easier to have homoplasy) Chapter 5, Mutation and Genetic Variation What was the expt. of inserting sequence into E. coli and yeast about? Why does polyploidy create new species? How are inversions cross over suppressors? How do now loci arise from gene duplication? What are Mutation Accumulation Lines Distinguish paralogues from orthologues Chapter 6, Population Genetics, HW and Selection and Mutation Explain HW again What is underdominance for fitness and why is it important What is overdominance for fitness and why is it important Explain the Sickle Cell example, why are Heterozygotes at an advantage Explain the different components of the Delta q equation Why is selection on a recessive allele more effective at high frequency than low Why are deleterious alleles maintained in human populations (does this negate the principal of natural selection)– Mutation Selection Balance, Drift