Transcript cardiovascular1

Rhett Johnson,
Director of
the Longleaf Alliance
Tyson Family Lecture on
the Preservation and Restoration of Southern Ecosystems
Thursday, Nov. 1, 7 p.m.
Olin Teaching Theater, Franklin W. Olin Building
Rhett Johnson, founder and president emeritus of the Longleaf
Alliance, which is dedicated to the conservation of longleaf pine
ecosystems, will talk about his efforts in the movement to
restore longleaf pine back to its native Southeastern range. The
program is the first of Wofford’s Tyson Family Lecture on the
Preservation and Restoration of Southern Ecosystems. It is
presented by Wofford’s Environmental Studies Program.
1QQ for 8:30 31Oct
Write each letter and circle the letter of correct statements.
a) Corticobulbar tracts control movements of the
face.
b) Huntington’s chorea is characterized by
involuntary purposeless jerky movements and is
associated with disruptions in cerebellar function.
c) Muscle spindle afferents monitor skeletal muscle
tension.
d) Gamma motoneurons cause extrafusal
myofibers to contract.
e) In the patellar stretch reflex, motoneurons for
antagonistic muscles would be inhibited.
1QQ #22 for 10:30
Write each letter and circle the letter of correct statements.
a) Corticobulbar tracts control movements of the
distal extremities.
b) Huntington’s chorea is characterized by
involuntary purposeless jerky movements and is
associated with disruptions in cerebellar function.
c) Muscle spindle afferents monitor skeletal muscle
tension.
d) Gamma motoneurons cause extrafusal
myofibers to contract.
e) In the patellar stretch reflex, motoneurons for
antagonistic muscles would be inhibited.
1QQ#22 for 11:30
Write each letter and circle the letter of correct statements.
a) Corticobulbar tracts control movements of the
distal extremities.
b) Deficits in the ability to point to a spot on a map
may indicate a disruption in cerebellar function.
c) Muscle spindle afferents monitor skeletal muscle
stretch.
d) Alpha motoneurons cause intrafusal myofibers to
contract.
e) In the crossed-extensor reflex, motoneurons for
flexor muscles in the contralateral leg would be
inhibited.
31 October 12
Begin Ch 12
Cardiovascular
Physiology
6 sections p. 353-433
2 CV labs:
1 Frog heart,
1 Human EKG and Blood Pressure
Was there ever a time when
you didn’t have a heart?
When did you get a heart?
Why did you need a heart?
S2
What does the Circulatory System Circulate?
Nutrients, water and gases that enter.
Substances that move from cell to cell.
Wastes that must be eliminated to the outside.
What if the heart stops beating?
5-10 seconds of zero blood flow to brain =
loss of consciousness (hypoxia)
5-10 minutes = permanent brain damage
S2
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What does the Circulatory System Circulate?
Water and ions
Nutrients: glucose, fatty acids, ketones, nucleic acids, amino acids
Wastes
Signaling molecules: hormones and cytokines
Security cells and molecules: leukocytes and antibodies
Gases: CO2 and O2
Formed Elements: Cells and Cell Fragments
– Erythrocytes, Leukocytes, Thrombocytes = Platelets
Other roles of the Cardiovascular System
Thermoregulation
Blood Clotting
Reproduction (ex: penile erection)
S1
Secretion
Reabsorption
Filtration
S4
Fig. 12.02
Arteries..away from heart
Veins..return to heart
Regional blood flow
determined by arteries
and arterioles.
Resting Cardiac Output =
5L/min for each side!
Red = highly
oxygenated blood
Blue = blood with
less oxygen.
S6
Pulmonary circuit
CO = 5 liters/min
Arterial Blood Pressure
Systemic Circuit
What’s
missing?
CO = 5 liters/min
Portal Systems
have a modified
sequence of vessels.
Resistance Vessels
Exchange Vessels
Microcirculation
Capacitance vessels
Hypothalamo-hypophyseal portal system
Hepatic portal system
What makes blood
move (flow)?
A Pressure Gradient
Flow = Q = ∆P
Where is the pressure the highest?
Where is the pressure the lowest?
What creates the pressure?
What deters flows?
Resistance
R = 8Lη/πr4
R = 8Lη/πr4
Smooth muscles determine radius
S8
F=Q=ΔP/R
Flow = Pressure gradient/Resistance
from Ohm’s Law (V=IR)
44
RR==8Lη/πr
8Lη/πr
Q= ΔP πr4
8Lη
Poiseulle’s equation
Double radius … 16x flow
Half radius….1/16th flow