Transcript Commercial Poultry Production and Feed Additives

Vitamins, amino acids positive
impact on productivity of birds,
digestion and the immune
systems
Dr. Najmul Shah, DVM, MSc(Hons), PhD
Product Manager Interchemie Holland
Interchemie Product portfolio
Veterinary Medicines
Water-soluble powders
Feed Additives
Nutritional watersoluble powders
Veterinary Medicines
Oral liquids
Feed Additives
Nutritional oral
liquids
Veterinary Medicines
Injectables
Veterinary Medicines
Miscellaneous
Feed Additives
Mineral blocks
Disinfectants
 Video
Poultry diet
 Energy
 Nutrient
 Efficient Production
Common feed ingredient in
poultry diets
•Cereals
•Fats and oils
Energy
sources
Protein
sources
•Soyabeans
•Animal meal (fish
meal)
•Canola
•Meat and bone meal
•Vitamin, amino acids &
minerals
•Feed enzyme
•Antioxidant
Feed Additive
FEED ADDITIVES
(Amino acids)
Amino acids
22 Amino Acids
•10 are essential amino acids
Amino acids comprise body protein
•All 22 amino acids are equally important
for protein (muscle) deposition
Essential amino acids
Essential amino acids
Essential amino acids
Essential amino acids
Essential amino acids
Amino acids & intestinal
physiology
Amino Acids & intestinal
physiology
Ref: Nichols & Bertolo 2008
•Synthesis of intestinal
protein
•Mucins
Extracted amino
acids
Mucins
•Glycosylated protein
•Secreted along
Intestinal epithelium by
exocrine goblet cells
•Protect the gut from
pathogens and antinutritional factors
•Rich in Threonine
•28-40% of total AA
Ser, Thr, Asp, Arginhibit invading
micro-organisms
Ref: Ushijima & Seto 1991
Amino acids and immunity
Deficiency
Impair immune
function
Increase the
sensitivity of animals
to infectious
challenges or
stressful conditions
Amino acids and immunity
Activation of T-Lymphocytes, Blymphocytes, natural killer cells
and macrophages
Amino acids
Production of
antibodies and
cytokines
Lymphocyte
proliferation
Amino acids and immunity
Methionine
Proven beneficial for the
immune system in chicken
infected with ND virus
T-cell proliferation
IgG secretion
Leucocytes migration
Antibody titer
Ref: Tsiagbe et al., 1987
Amino acids and immunity
Lysine
Synthesis of cytokines
Proliferation of lymphocytes
Optimum function of immune
system in response to
infection (Konashi et.al., 2000)
An inadequate supply of Lys
would reduce antibody
response and cell-mediated
immunity in chicken
(Chen et al., 2003)
Amino acids and immunity
Arginine
NO (nitric oxide) production
of macrophages, anti-tumor
properties
Increased lymphoid organ
weights & percentage of CD8+
cells
Enhanced heterophil to
lymphocyte ratio in response to
viral infection (Kidd, 2004)
Vitamins
Vitamins
Utilization of
nutrients
Metabolism
Major
Functions
Vitamins
Therapeutic
Prophylactic
Vitamins deficiency syndrome
is gradual process
Marginal
Sub-clinical
Clinical
Vit. Def.
Syndrome
Fat Soluble Vitamin
Vitamin A
Decreased egg
production,
weakness and
lack of growth
Formation and preservation of
function of epithelial tissues and
mucous membranes
Important for fertility
Essential for vision
Fat Soluble Vitamin
Vitamin D
Thin shelled
eggs, reduced
egg production,
retarded
growth, rickets
Role in the uptake of calcium and
phosphate from intestine
Regulates calcium and phosphate
metabolism
Essential for the normal
development of skeleton and teeth
Fat Soluble Vitamin
Vitamin E
Enlarged hocks,
encephalomalacia
(crazy chick
disease)
Intracellular antioxidant
Stabilise unsaturated fatty acids
Prevent toxic oxidative destruction
Water Soluble Vitamin
Riboflavin
(B2)
Curly-toe
paralysis, poor
growth and
poor egg
production,
diarrehea
The B vitamins include vitamin
thiamin, riboflavin, niacin,
pantothenic acid, pyridoxine, biotin,
folic acid, and cyanocobalamin.
Water Soluble Vitamin
Choline
Poor growth,
fatty liver,
decreased egg
production
As a constituent of phospholipids,
i.e. it is essential in the building and
maintenance of cell structure
In fat metabolism in the liver, i.e.
utilisation and outward transport of
fat
Water Soluble Vitamin
Vitamin B12 Anaemia, poor
growth,
embryonic
mortality
Involved with nucleic acid synthesis,
carbohydrate and fat metabolism
and methyl synthesis
When multivitamins, amino acids and
minerals supplementation are useful
Chicks &
brooding
period
Stress
Production
Prevention
When multivitamins, amino acids and
minerals supplementation are useful
Chicks & brooding period
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Good start of chicks
Good enteric health
High nutritional needs
Underdevelop immune system
Poor thermoregulation system
Absorption of yolk
STRESS
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Heat Stress
Disease
Transportation
Cold stress
Vaccination
Debeaking
Deworming
COST OF STRESS
Mortalities
Low Fertility
Lower resistance to disease
Metabolic disorders
Productivity Losses
PRODUCTIVITY LOSSES
(HEAT STRESS)
Depressed appetite
FCR down by 6-12%
Slower growth upto 25%
Lower egg yield 8-10%
Inferior Carcase quality
Indigestibility
Loss of acid-base balance
When multivitamins, amino acids and
minerals supplementation are useful
Production
• High production
• Low production
• Poorly birds
When multivitamins, amino acids and
minerals supplementation are useful
Prevention
• Prevention of diseases like ND,
Gumboro
• Prevention of nutritional disorders
like Perosis, Rickets, Curled toe
paralysis, Encephalomalcia,
muscular dystrophy, fatty liver
INTERCHEMIE PRODUCTS DURING
STRESS (HEAT STRESS)
Introvit-C-200 Oral
Features
Vitamin C
Advantages/Benefits
Antioxidant
Helps to convert iron into a chemical form that is more easily
absorbed from the digestive tract
It also improves eggshell quality via its role in the formation of
the shell's organic matrix.
Reduces the effects of stress increases feed utilization and daily
weight gains rehydrates the body of the animal
Helps in Heat Stress
Accelerates wound healing
Immune System: Vitamin C makes the epithelial tissues in the
mouth less permeable to bacteria
Feed Conversion ratio (FCR)
FCR
1.85
1.81
1.8
1.75
1.73
1.7
1.65
1.59
1.6
1.55
1.5
1.45
Control no heat
Control under
heat stress
Introvit-C-200
Oral
FCR
INTERCHEMIE
PRODUCTS DURING
STRESS
Product
Description
Stressol Oral
Vitamins
Amino Acids
Minerals
Stressol Oral
Product
Stressol Oral
Main Benefits
To reduce stress (Heat, vaccination, Disease,
transport, high humidity)
Growth promoters
Production promoters
Improvement of gut health
Help in gut regeneration
Energy metabolism
Stressol Oral
Product
Stressol Oral
Main Benefits
Maintenance of epithelial cells in good condition
(skin and the linings of the digestive, reproductive,
and respiratory tracts)
Improve feed conversation rate
Increase weight gain and performance
Maximized economical benefits
Dosage
1 Litre per 2000 litres of drinking water for 3-5 days
Broiler production
Intertonic
Oral
Introvit-ES-100
oral
Introvit A+ oral
Day 21
Day 28
3D-V-3D
Day 1
Vaccination (NDV)
Stimulate Liver & Renal function
Energy metabolism,
Fat into Energy
•Chicks from Hatchery
•Good start of chicks
•To ease transportation
stress
•To reduce vaccine stress
•Increased antibody titer
•To support early growth
•Improve immune response
•Maintain gut integrity
Brooding Period
To improve Immunity
Anti-stress
Antioxidant
•Improve the performance
of broiler under fast
production stress
• Important for gut functions
•Improve FCR
Growth period
Day 1-7
Day 8 to Day 45
Vaccination (NDV & IBD)
Day 35
Day 14
Aminogrow ora
Vitol-140 oral
Introvit A+ Oral
Product
Description
Introvit A+ Oral
Vitamins
Amino acids
Fat soluble vitamin
Building blocks of protein
Water soluble vitamin
Essential amino acids
Introvit A+ Oral
Product
Introvit A+ Oral
Main Benefits
Good start of chicks and provide energy
Prevention of early chick mortality
Stimulate immune system
Develop resistance against pullorum, salmonelosis
and colibacillosis
Improve digestibility
Improve Yolk absorption
Source of early metabolism
Provide energy
Dosages
Poultry 1litre per 2000 litre drinking water 3-5 days
Intertonic oral
• Sorbitol
• Carnitine hydrochloride
• Betaine
• Choline chloride
• D-panthenol
• Magnesium sulphate
Intertonic oral
Product
Intertonic oral
Main benefits
To improve the oxidation of fatty acids to achieve
energy (Energy metabolism, Fat into Energy)
Stimulate Liver & Renal functions
Intertonic oral
Product
Intertonic oral
Main indications
To reduce production stress
Prevent Fatty Liver
Instant Nutrients, Improve Digestion
To improve growth
Dosage
1 Kg per 1000 litre drinking water for 3-5 days
Feed intake analysis of Group A (Control) N=50 chicks and
Group B (Intertonic oral) N=50 chicks
4200
4190
4180
4170
Group A (Control)
4160
4150
Group B (Intertonic
oral)
4140
4130
4120
4110
Feed intake 1-42 days
Body weight gain analysis of Group A (Control) N=50 chicks and
Group B (Intertonic oral) N=50 chicks
2250
2200
2150
2100
Group A Control
2050
2000
Group B Intertonic
oral
1950
1900
1850
1800
BW 1-42 days
FCR analysis of Group A (Control) N=50 chicks and Group B
(Intertonic oral) N=50 chicks
2.2
2.15
2.1
2.05
2
Group A (Control)
1.95
Group B (Intertonic
oral)
1.9
1.85
1.8
1.75
1.7
FCR 42 days
Vitol-140 oral
Product
Description
Vitol-140 Oral
Vitamin A
Vitamin D3
Vitamin E
Vitol-140 Oral
Product
Vitol-140 Oral
Main Benefits
Antioxidant, preventing oxidation of lipids within
membranes
Strong immune response with enhance resistance
of poultry to infectious diseases
Highly effective in reducing toxicity of metals such
as silver, arsenic and lead, and shows slight
effects against cadmium and mercury toxicity(E)
Increase Egg Production
Strong bones and good egg shell quality
Improve calcium and Phosphorus metabolism
Dosages
1 litre per 8000 litres of drinking water
Introvit-ES-100 Oral
Product
Introvit-ES-100
Description
Vitamin E
Sodium selinite
Introvit-ES-100 Oral
Product
Introvit-ES-100 Oral
Main Benefits
Antioxidant
Enhances immune responses
Increases antibodies titer
Enhances recovery from disease
Dosages
1 litre per 4000 litres of drinking water
Aminogrow oral
Product
Description
Aminogrow
Amino acids
Building blocks of protein
Essential amino acids
Aminogrow Oral
Product
Aminogrow Oral
Main Benefits
Synthesis of intestinal proteins which are mainly
secreted into the lumen as mucus which protect the
gut from pathogens and antinutritional factors
Amino acids in Aminogrow such as Ser, Thr, Asp and
Arg have been suggested to inhibit invading
microorganisms
Aminogrow regulate activation of T-lymphocytes, Blymphocytes, natural killer cells and macrophages,
lymphocyte proliferation, as well as the production of
antibodies and cytokines
Dosages
1 litre per 4000 litres of drinking water
Fig. 1 Feed intake analysis of Group A (Control) N=5000
chicks and Group B (Interchemie feed additives
programme) N=5000 chicks during the early and later
stage of broiler chick life.
5000
4500
4000
3500
3000
Grams 2500
2000
1500
1000
500
0
Group A (Control)
Group B
(Interchemie Feed
additives
Programme)
Feed intake Day Feed intake Day
21
42
Fig. 2 Body weight gain analysis of Group A (Control)
N=5000 chicks and Group B (Interchemie feed additives
programme) N=5000 chicks during the early and later
stage of broiler chick life.
3000
2500
Group A Control
2000
Grams
1500
Group B
(Interchemie
Products
Programme)
1000
500
0
BW 21 days
BW 42 days
Fig. 3 FCR analysis of Group A (Control) N=5000 chicks
and Group B (Interchemie feed additives programme)
N=5000 chicks at Day 42
2.5
2
Group A (Control)
1.5
Group B
(Interchemie
Products
Programme)
1
0.5
0
FCR 42 days
Layer production
Introvit A+ Oral
Day 1
Intertonic oral
8-10 wk
10-12wk
12-14 wk
14-16 wk
16-18 wk
Day 21
Vitol-140 oral
Introvit-C ora
Introvit-ES- 10
Introvit D3 or
Growing and
vaccination
•Good start of chicks
•To ease transportation stress
•To reduce the vaccine stress
Week 2-16/18
•To ease vaccine stress and
increase immune response
•To improve performance
•Proper utilization of fat and
energy metabolism
•Improve bone development
•To improve egg production
•To prevent multivitamins, amino
acids and minerals deficiencies
•To reduce production stress
•Improved feed conversion ratio
•Improve egg shell quality
Chicks from Hatchery
Laying stage
Brooding period
Day 1
16/8 Weeks +
20 wk
24 wk
28 wk
32 wk
36 wk
Day 14
Vitol-140 Oral
Introvit B-complex oral
Stressol oral
Intertonic oral
Introvit D3 oral
Vitol-140 oral
Feed additives 36 weeks
programme effects in layers
Feed Conversion
Ratio (FCR)
Egg Quality
Egg weight
Feed Conversion Ratio(FCR)
1.95
1.9
1.85
1.8
Interchemie feed
additive programme
36 wks
1.75
1.7
Control
1.65
1.6
1.55
1.5
1.45
FCR
Egg Quality
3
2.5
2
Interchemie feed
additive programme
36 wks
1.5
Control
1
0.5
0
Cracked
Broken
Egg Weight
74
72
70
68
66
64
Interchemie
Prograamme 36 wks
62
Control
60
58
56
54
Egg weight (gms)
Costs & return
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Vitol-140 Oral
Introvit ES 100
Stressol Oral
Introvit A+ Oral
Introvit-B-complex Oral
Intertonic Oral
Calcimin Oral
Respimint Oral
•Good start of Chick life
•Protect from diseases
•Strong immune system
•Rapid recovery from diseases
•Healthy animals
•More meat and egg production
•Rapid growth
•Improve FCR
•High profitability
Thank you for
your attention!