Transcript Dr Mworozi - Rabies presentation 12-02-2013

Review of Rabies cases in the
Paediatric Infectious Disease Unit,
Mulago Hospital
Dr Edison Mworozi Arwanire & Joseph Rujumba
Department of Mulago Hospital
Email: [email protected] and [email protected]
Presented at the Uganda Medical Association & Uganda Veterinary
Association 1st International ONE Health Conference 14-16 February
2015 at Hotel Africana, Kampala
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Overview
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Background
Objectives
Methods
Results
Conclusion
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Background
• The Decade of Vaccines Collaboration commits to
improving the health and lives of women and
children (WHO, UNICEF, NIAID, GAVI Alliance, and Bill
& Melinda Gates Foundation 8 October 2012)
• Decade of Vaccines Collaboration is a vision to
reach all people with the vaccines they need””
(WHO 2013)
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Background - Rabies
• A zoonotic disease caused by the Rabies Virus
leading to Rabies encephalitis which is almost
always fatal in humans.
• Despite being a preventable disease by
vaccinating primarily animals and susceptible
humans, Rabies affects about 55,000 people
globally the majority being in Asia and Africa.
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Background to Rabies ct’d
• It remains a relatively common problem in
developing countries including Uganda especially
in children.
• Is associated with a high case fatality rate.
• Mainly due to lack of immunization of domestic
animals particularly dogs and humans especially
children bitten by such animals due to limited
awareness and access to Rabies Vaccine.
• Inadequate/lack of PEP
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Objective
To document and highlight the fact that Rabies is a
disease of public health importance in children in
Uganda.
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Methods
• Conducted a records review of Rabies cases
admitted to the pediatric infectious diseases unit
of Mulago National Referral Hospital from 1st
January 2010- 31st December 2012 documenting
– address,
– age
– sex
– duration of hospitalization and
– outcome of the cases.
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Results
• From 2010-2012 a total of 13 Children with
Rabies were admitted
• Majority, 8/13(61.5%) were from Kampala
District.
• Age range was 1yr and 4 months to 12yrs with an
average age of 7.6 yrs .
• Almost all of the cases had been bitted by un
immunized domestic dogs.
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Results
ct’d
• By age category 8/13(61.5%) were aged ≥
7years, while 4/13(30.8 %) were aged 5-6 years
• By gender, 11/13(85%) were males.
• All the 13 children (100%) died.
• The average duration of stay in hospital was 3.8
days (range 1-13 days)
• The majority 7/12(58%) died within 1-3 days of
admission.
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Conclusion
• Rabies infection in humans especially children is
a public health problem in Uganda with high
mortality calling for a concerted effort by
veterinary & health professionals to vaccinate all
susceptible domestic animals especially dogs
and human beings particulary children bitten by
such animals.
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Thank you for your attention
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