Transcript EDEN

Emerging, vector-borne diseases in a
changing European environment
Renaud Lancelot (CIRAD) and Guy Hendrickx (Avia-GIS)
EDEN
Importance of vector-borne diseases
Vector-borne diseases are a significant
part of emerging infectious diseases
and their relative importance is
increasing
They are highly sensitive to local and
global environmental changes:
• Climate change
• Intensification of commercial
exchanges and international travels
• Land-cover and land-use changes
• Socio-economic changes
14%
29%
12%
28%
40%
45%
Jones et al., 2008. Global trends in emerging infectious diseases.
Nature, 451 : 990-993. http://dx.doi.org/10.1038/nature06536
EDEN call (2004)
The aim is to identify, evaluate and catalogue European
ecosystems and environmental conditions linked to global
change, which can influence the spatial and temporal
distribution and dynamics of pathogenic agents.
A coordinated European approach is needed to provide predictive
emergence and spread models including global and regional
prevention, early warning, surveillance, and monitoring tools
and scenarios.
Coordination with international organizations and third-world
countries is essential.
EDEN integrated project
• 24 countries,
• 49 partners,
• 80 scientific teams,
• 120 field sites,
• 60 PhD Students,
• 200 research years
EDEN integrated project
49
24
Data Management &
Information Systems (WP6.1)
Low Resolution Remote Sensing &
Spatial Modelling (WP6.2)
High Resolution Remote Sensing &
Environmental Change Monitoring (WP6.2)
Mathematical Modelling &
Disease Establishment and Spread (WP6.3)
Africa
WNV-RVF
Malaria
West
Nile
Leishmania
- grouped under WP6 -
Rodent
Borne
Horizontal Integration Teams
Tick
Borne
Vertical Disease Sub-Projects
For each indicator disease, field studies
are conducted to understand
patterns and processes:
WP1 – Landscapes/biotopes
WP2 – Vectors
WP3 – Public health
WP4 – Animal hosts/reservoirs
WP5 – Integrated data analysis
Biodiversity &
Impact on Disease Spread (WP6.3)
WP8 Training, Dissemination, Management & Coordination
Tools and
Scenarios
- WP7 -
EDEN findings
A key outcome of EDEN is that many of currently observed
changes in disease occurrence are driven by complex
multifactorial causes and can often not simply be linked to
a single cause.
Socio-economic factors affecting behavior and contacts
between hosts, vectors and pathogens often appear to be
more important drivers of change than climatic factors.
This complexity should not be overlooked in disease risk
studies and public health policy making.
e.g. Tick-borne encephalitis
Conceptual model and empirical evidence of causes of spatio-temporal
heterogeneity in TBE epidemiology in Central and Eastern Europe
(Sumilo D,
Asokliene L,
Bormane A,
Vasilenko V,
Golovljova I,
Randolph S
2007. PloS
ONE, 2: e500)
EDEN next
One of the main EDEN assets is to have generated a
pan-EU network of experts, including an extensive
PhD network, in research on vectors and vectorborne diseases = VBD past-present-future.
The EDEN network is now considered by publichealth agencies as ‘incontournable’ on the topic of
vector-borne diseases.
This already yielded spin-off projects with ECDC and
ESA. The EDEN consortium will also coordinate
replies to upcoming FP7 calls.
Thank you for your questions
Welcome at the EDEN International
Conference on emerging vector-borne disease
in a changing European Environment
Montpellier (France), 10-12 May 2010