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Creutzfeld Jakob Disease
Alexia Constanza Espiño Álvarez
What’s CJD?
•CJD is a form of brain damage that
causes a rapid decrease of mental
function and movement.
•CJD is believed to
result from a
protein called a
prion.
•CJD
can beare
grouped
intotypes
classicofor new
•There
several
variant disease.
CJD. The disorder is rare,
The occurring
classic types
of CJD1are:
in about
out of 1
million CJD
people.
It usually
first cases. It
Sporadic
makes
up the most
between
ages
20
oftenappears
occurs for
no known
reasons.
and 70, with average age and
 Familial CJD results when a person
the symptoms start in the late
inherited
50s. the abnormal protein (prion).
This type is rare.
The new variant CJD (nvCJD) is an
infectious form that is related to mad cow
disease
Symptoms
Here is a list of some of the common
signs and symptoms of Creutzfeldt
Jakob Disease:
-Muscle weakness on one side of body
-Blindness
-Muscular coordination problems
-Confusion
-Mutism
-Decreased abdominal reflexes
-Dementia
-Personality changes
-Progressive muscular atrophy
-Depression
-Rapid involuntary eye movements
-Disorientation
-Rigidity
-Hallucinations
-Insomnia
-Involuntary movements
-Sensory disturbances
-Speaking difficulty
-Memory failure
-Tremor
-Mental deterioration
-Unusual sensations
Diagnosis

Tests used to diagnose this condition may
include: A neurological and motor system examination shows
muscle spasm.
-EEG : electroencephalogram.
EEG:
There
-Spinal
tapis loss of coordination related to visual-spatial
electroencephalogram
perception changes and changes in the cerebellum,
the

area
the brain
controls
coordination.
Ultimately,
theof
disease
can that
only be
confirmed
by
brain biopsy or autopsy.
An
eye examination shows areas of blindness.
Lumbar Spinal
Tap
Treatment

Here is a list of treatments and procedures that are commonly used to
treat Creutzfeldt Jakob Disease:
-Blood Transfusion.
There
is no known cure.
-Clonazepam: a highly potent anticonvulsant and muscle relaxant.
-Deep Brain Stimulation.
Medications may be needed to control
-Opiate drugs.
aggressive behaviors, like: sedatives,
antipsychotics…
-Sodium valproate: an anticonvulsant,
•Also, controlling aggressive or agitated behavior, and
meeting physiologist, support from the family may be good
for people with CJD.
Prevention
To
reduce the already very low risk of CJD
transmission people should never donate blood,
tissues, or organs if they have suspected or
confirmed.

Most countries now have strict
guidelines for management of infected
cows and strict restrictions regarding
what they are fed, to avoid the potential
for transmission of CJD to humans.
What research is taking place?

Many researchers are studying CJD

They are investigating how CJD can be
transmitted and how it damages the brain.

They want to know the development of this
disorder to find treatments and a effective
cure
News
Blood test for
vCJD
'unrealistic'
In Jaffrey, a
woman’s death is
probed
Former Buffalo
mayor died from
brain disease
CJD
14 cases of
'mad cow
disease' found
in NI
A video about CJD