Transcript Hot Zone Part 1

The Hot Zone
By Richard Preston
Part One:
The Shadow of Mt. Elgon
Mount Elgon
Mount Elgon
Mt. Elgon is Kenya's second highest mountain
Lies on the Kenya-Uganda Border
It is an ancient eroded volcano with a huge
caldera
Kitum Cave
Map of Kitum Cave
Elephants and Bats
Elephant Scrapings
Insects And Rock Hyrax
Marburg
Filovirus
Related to Ebola
Originated in Africa
1st Outbreak in Germany
Level 4 biocontainment
Causes headache, muscle ache, fever, vomiting,
hemorrhaging, death
USAMRIID
United States Army Medical Research Institute on
Infectious Disease
Chemturion Suit
5 Types of Ebola
Ebola Virus Disease (EVD)
1. Ebola Zaire
2. Ebola Sudan
3. Ebola Reston
4. Ebola Ivory Coast
5. Ebola Bundibugyo
WARNING:
UPCOMING
GRAPHIC PICTURES
Ebola Symptoms
Ebola Zaire
Most deadly form of Ebola
90% fatality rate
There have been more outbreaks of Ebola-Zaire than any
other type of Ebola
1st outbreak was in 1976 in Yambuku, Zaire
Index Case—Mabelo Lokela
Checked into the local hospital with a fever. One of the
nurses assumed he had malaria and gave him a quinine
shot. When he returned home from the hospital and died,
the women in his family conducted a traditional African
funeral for him. In preparation for this funeral, they
removed all the blood and excreta from his body with their
bare hands. Most of the women in his family died soon
afterward.
Ebola Sudan
Index case—Mr. Yu. G.
Yu. G. worked at a cotton plantation and probably
passed it to coworkers. Yu. G. died quietly at
home, however, one of his coworkers infected a
number of others.
Ebola Reston
You will learn more about this outbreak in the next
section
Ebola Ivory Coast
1st outbreak in 1994 (after The Hot Zone was
written)
A scientist became ill after conducting an autopsy
on a wild chimpanzee. The scientist recovered.
Not much is known about this form of Ebola since
only one case of it has been discovered.
http://www.crystalinks.com/ebola.html
Ebola Bundibugyo
Outbreak occurred in December 2007-January
2008
38 dead, 153 infected in an outbreak in the
Bundibugyo district in Western Uganda
Part Two:
The Monkey House
Reston, Virginia
Reston, Virginia
Reston, Virginia
Reston Primate Quarantine Unit
Quarantine monkeys for 1 month
Sent monkeys all over the U.S. for laboratory
research
Intended to prevent the spread of infectious
diseases
Crab Eating Monkeys
Crab Eating Monkeys
Long Tailed Macaques
Came from the island of Mindanao in the
Philippines
Sent to Manila, then to Amsterdam, then to New
York
Ended up in Reston, Virginia
Simian Hemorrhagic Fever (SHF)
Deadly for monkeys
Harmless to humans
Can spread quickly
Symptoms are similar to Ebola
Extremely deadly
Nancy Jaax (USAMRIID)
Jerry Jaax (USAMRIID)
CJ Peters (USAMRIID)
Tom Geisbert (USAMRIID)
Peter Jahrling (USAMRIID)
Joe McCormick (CDC)
Fred Murphy (CDC)
The Institute
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