Transcript Annual report on tuberculosis surveillance 2013

Tuberculosis in the UK
2013 report
Tables and figures slide-set
1. Tuberculosis case reports, UK, 2000-2012
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Tuberculosis in the UK: 2013 report
Figure 1.1: Tuberculosis case reports and rates, UK,
2000-2012
10,000
15
14
9,000
13
8,000
12
Number of cases
10
6,000
9
8
5,000
7
4,000
6
5
3,000
Rate (per 100, 000)
11
7,000
4
2,000
3
2
1,000
1
0
0
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
Year
Number of cases
Rate per 100,000
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.2: Tuberculosis case reports and rates by country,
UK, 2012
10,000
18.0
Number of cases
9,000
Rate per 100,000
16.0
8,000
14.0
Number of cases
12.0
6,000
10.0
5,000
8.0
4,000
6.0
Rate (per 100, 000)
7,000
3,000
4.0
2,000
2.0
1,000
0
0.0
England
Northern Ireland
Wales
Scotland
Total
Country
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.3. Three-year average tuberculosis
case rates by local area*, UK, 2010-2012
*England – Local authorities, Wales and Scotland – Health
Boards, NI – data not available
London
© Crown copyright and database rights 2013 Ordnance Survey 100016969
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections
(ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.4: Tuberculosis case reports and rates by region*,
England, 2012
4,000
3,500
50
41.9
Number of cases
45
Rate (per100,000) and 95% CI
40
3,000
Number of cases
2,500
30
2,000
25
19.4
20
1,500
1,000
11.3
11.5
9.3
15
10.8
7.8
5.8
500
0
Region
* HPA region
CI – 95% confidence intervals
Source: Enhanced Tuberculosis Surveillance (ETS), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report
10
5
0
6
6.4
Rate (per 100, 000)
35
Figure 1.5: Tuberculosis case reports and rates by PHE
Centre, England, 2012
4,000
50
Number of cases
Rate per 100,000
45
41.8
3,500
40
3,000
2,500
30
2,000
25
19.3
1,500
14.5
11.0
1,000
6.3
500
20
17.3
11.9
10.7
7.8
7.4
4.7
6.4
3.9
10
0
PHE Centre
CI - confidence intervals
Source: Enhanced Tuberculosis Surveillance (ETS), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report
6.5
15
5
0
7
11.4
Rate (per 100, 000)
Number of cases
35
Figure 1.6: Tuberculosis case reports by place of birth
and country, UK, 2012
Non UK-born
UK-born
100%
90%
2,020
Percentage of cases
80%
39
142
56
48
185
73
70%
60%
50%
40%
5,819
30%
20%
10%
0%
Country (% where place of birth known)
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.7: Tuberculosis case reports by place of birth
and PHE Centre, England, 2012
Non UK-born
UK-born
100%
566
90%
Percentage of cases
80%
192
58
130
101
37
340
80
73
79
100
43
70%
60%
50%
2,807
40%
30%
352
92
326
73
298
701
168
221
227
101
35
20%
0%
PHE Centre (% where place of birth known)
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
Tuberculosis in the UK: 2013 report
120
192
10%
9
45
115
Figure 1.8: Non UK-born tuberculosis case reports by
time since entry to the UK to tuberculosis diagnosis,
UK, 2012
600
Number of cases
500
400
300
200
100
0
0
5
10
15
20
25
30
35
Years since entry to diagnosis
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
40
45
50+
Table 1.1: Most frequent countries of birth for non UK-born
tuberculosis cases, UK, 2012
Country of birth
Number of Percentage
cases
of cases*
Median time since
entry UK (IQR)**
India
1,858
30.7
4 (2 - 13)
Pakistan
1,091
18.0
7 (2 - 21)
Somalia
380
6.3
8 (3 - 12)
Bangladesh
276
4.6
7 (2 - 23)
Nepal
216
3.6
2 (1 - 5)
Nigeria
184
3.0
5 (1 - 10)
Philippines
136
2.3
5 (2 - 9)
Zimbabwe
132
2.2
9 (7 - 11)
Kenya
98
1.6
13 (6 - 40)
Sri Lanka
98
1.6
7 (2 - 15)
Eritrea
87
1.4
4 (2 - 5)
Romania
78
1.3
2 (0 - 4)
Afghanistan
75
1.2
5 (2 - 10)
Poland
71
1.2
5 (2 - 7)
Others (each <1%)
1,265
21.1
5 (1 - 13)
Total*
6,045
100
6 (2 -13)
* Where country of birth was known; **Years
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.9: Tuberculosis case reports and rates by ethnic group and place
of birth, England, Wales and Northern Ireland, 2012
300
2,000
Number of cases
243
Rate (per 100,000)
250
215
200
Number of cases
178
1,000
150
123
68
500
100
53
28
36
31
39
18
12
3
30
7
6
50
27
9
0
UK-born
Mixed / Other
Chinese
Bangladeshi
Pakistani
Indian
Black-Other
Black-Af rican
Black-Caribbean
White
Mixed / Other
Chinese
Bangladeshi
Pakistani
Indian
Black-Other
Black-Af rican
Black-Caribbean
White
0
Non UK-born
Place of birth/Ethnic group
Source: Enhanced Tuberculosis Surveillance (ETS), Rates by place of birth calculated using Labour Force Survey population estimates.
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Rate (per 100,000)
1,500
Figure 1.10: Tuberculosis case reports and rates by age
group and place of birth, UK, 2012
1,200
140
1,100
Number of cases
900
100
800
700
80
600
60
500
Rate (per 100,000)
120
1,000
400
40
300
200
20
100
0
0
Age group (years)
UK-born
Non UK-born
Rate in UK-born
Rate in non UK-born
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
800
40
700
35
600
30
500
25
400
20
300
15
200
10
100
5
0
0
Rate (per 100,000)
Number of cases
Figure 1.11: Tuberculosis case reports and rates by age
group and sex, UK, 2012
Age group (years)
Male cases
Female cases
Rate in males
Rate in females
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.12: Tuberculosis case reports and rates by place
of birth, UK, 2000-2012
7,000
120
98
88
Number of cases
5,000
100
91
93
86
85
89
86
82
76
84
80
77
80
4,000
60
3,000
40
Rate (per 100,000)
6,000
2,000
1,000
20
4
4
4
4
4
4
4
4
4
4
4
4
4
0
0
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
Year
UK-born
Non UK-born
Rate UK-born
Rate Non UK-born
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.13: Proportion of tuberculosis case reports
by site of disease (pulmonary/extra-pulmonary), UK,
2000-2012
100
90
80
Percentage of cases (%)
70
60
50
40
30
20
10
0
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
Year
Pulmonary
Extra-pulmonary
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
2010
2011
2012
Table 1.2: Tuberculosis case reports by site of disease,
UK, 2012
Site of disease*
Number of cases
4,563
Percentage**
52.1
Extra-thoracic lymph nodes
1,872
21.4
Intra-thoracic lymph nodes
946
10.8
Other extra-pulmonary
619
7.1
Pleural
651
7.4
Gastrointestinal
471
5.4
Bone – spine
Cryptic ±
394
4.5
46
0.5
±
197
2.3
Bone – other
218
2.5
CNS – meningitis
187
2.1
Genitourinary
137
1.6
CNS – other
80
0.9
Laryngeal
16
0.2
Unknown extra-pulmonary
15
0.2
Pulmonary
Miliary
*With or without disease at another site
±For
**Percentage of cases with known sites of disease (8751)
Scotland cases, this includes both cryptic and miliary site
CNS - Central Nervous System
Total percentage exceeds 100% due to infections at more than one site
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 1.14: Child to adult ratio in notifications rate, UK,
2000-2012
Ratio: case notification rate children/adults
0.40
0.30
0.20
0.10
0.00
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
The child-to-adult ratio is the ratio of the case notification rate in children under 15 years of age,
to that in adults. A declining trend in the ratio suggests a decrease in ongoing transmission
(European Centre for Disease Prevention and Control).
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
2. Microscopy, culture confirmation, speciation
and drug susceptibility
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Tuberculosis in the UK: 2013 report
Figure 2.1: Proportion of cases with first line drug resistance
or MDR-TB, UK, 2000-2012
9
8
7
Proportion of cases (%)
6
5
4
3
2
1
0
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
Year
Isoniazid Resistant
Multi-drug Resistant
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
2010
2011
2012
Table 2.1: Number and proportion of tuberculosis cases
with drug resistance by age group, UK, 2012
Isoniazid
Resistant to any
Multi-drug
resistant
first line drug*
resistant
Age Group
Total**
n
%
n
%
n
%
0-14
10
9.7
10
9.7
7
6.8
103
15-44
240
7.2
264
7.9
65
2.0
3,333
45-65
77
7.6
78
7.7
8
0.8
1012
65+
24
3.4
27
3.8
1
0.1
703
*First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide**First line drugs – isoniazid, rifampicin, ethambutol and pyrazinamide
**Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Table 2.2: Proportion of tuberculosis cases with drug
resistance by previous history of tuberculosis, UK,
2012*
Isoniazid
resistant
Resistant to any
first line drug**
Multi-drug
resistant
n
%
n
%
n
%
Yes
28
11.5
31
12.7
14
5.7
244
No
304
6.7
329
7.2
62
1.4
4570
* Cases with unknown previous history of tuberculosis are excluded
** First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide
$ Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
22
Total $
Previous
history of TB
Tuberculosis in the UK: 2013 report
Table 2.3: Number and proportion of tuberculosis cases
with drug resistance by place of birth, UK, 2012*
Place of birth
Isoniazid
Resistant to any
Multi-drug
resistant
first line drug**
resistant
Total $
n
%
n
%
n
%
64
5.3
70
5.8
9
0.7
1,216
Non-UK born
274
7.4
296
8.0
71
1.9
3,709
Central Europe
6
4.3
6
4.3
5
3.6
139
East Europe
19
35.2
20
37.0
13
24.1
54
West Europe
10
10.4
10
10.4
5
5.2
96
East Mediterranean
2
4.9
3
7.3
0
0.0
41
East Asia
4
6.5
4
6.5
0
0.0
62
South Asia
151
7.0
163
7.6
31
1.4
2,144
South East Asia
19
10.1
23
12.2
2
1.1
189
North Africa
0
0.0
0
0.0
0
0.0
35
Sub-Saharan Africa
51
6.2
54
6.6
13
1.6
819
North America and Oceania
0
0.0
0
0.0
0
0.0
5
South and Central America and the Caribbean
7
10.3
8
11.8
0
0.0
68
UK born
* Cases with unknown previous history of tuberculosis are excluded
** First line drugs - isoniazid, rifampicin, ethambutol and pyrazinamide
$ Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 2.2: Proportion of tuberculosis cases
isoniazid and multi-drug resistance by place of birth
and previous history of tuberculosis, UK, 2012*
14
20
No previous history of TB
12
Proportion of cases (%)
Previous history of TB
8
10
13
8
6
243
54
4
2
54
1
7
0
UK-born
Non UK-born
Isoniazid resistant
UK-born
Non UK-born
Multi-drug resistant
* Cases with unknown place of birth and unknown previous history of TB are not included
Culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 2.3: Proportion* of multi-drug resistance cases
from Eastern Europe, South Asia and Sub-Saharan
Africa with additional resistance, UK, 2012
100
90
Eastern Europe
Proportion of MDR cases (%)
80
South Asia
Sub-Saharan Africa
70
8
8
8
60
14
50
40
4
30
20
5
2
2
3
2
2
10
0
0
0
0
0
Resistant to all 1st Resistant to at least Resistant to at least Resistant to at least
Extensively drug
line drugs (H, R, E one second line drug one injectable drug one Fluoroquinolone resistant tuberculosis
and Z)
(XDR)
*Proportion were calculated out of those who were tested
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
3. Strain typing, 2010-2012
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Tuberculosis in the UK: 2013 report
Table 3.1: Number and proportion of culture confirmed
cases typed or with 23 loci typed by year and country
England, Wales and Northern Ireland‡
§
England
Wales
#
Northern Ireland
Estimated proportion
Number of
Number of
Number of
of
cases
likely
due
to
clusters
by cluster
cases
clusters
$
size
clustered**
recent transmission
Culture
confirmed
cases
Cases with a
strain type*
n
n (%)
n
n
%
2-4
5-9
10+
14,692
11,745 (79.9)
6,113
1,401
40
1,110
198
93
14,248
11,491 (80.6)
5,973
1,371
40
1,084
198
89
296
167 (56.4)
26
12
8
12
0
0
148
87 (58.8)
21
9
14
9
0
0
* Culture confirmed cases with a MIRU-VNTR profile with at least 23 complete loci
** Clustered cases are clustered within geographical area
$ Calculated using the n-1 method (number of cases in a cluster-number of clusters/number of cases with a strain type)
‡ The number of clusters in England, Wales and Northern Ireland is higher than the sum of all clusters in the three countries because it
includes clusters that span more than one country
§ The number of clusters in England is higher than the sum of all PHEC clusters because it includes clusters that span more than PHEC
# The number of culture confirmed cases in Northern Ireland reported here is less than the 157 culture confirmed cases known about locally
Source: Enhanced Tuberculosis Surveillance (ETS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Table 3.2: Number of tuberculosis cases and proportion
of clustering stratified by place of birth, 2010-2012
England, Wales and
Northern Ireland$
UK-born‡
§
Non UK-born
Culture
confirmed
cases
Cases with a
strain type*
Number
Estimated proportion of
Number of
of cases
cases likely due to
clusters
clustered
recent transmission**
Proportion of
cases with a
unique strain
n
n (%)
n
n
%
%
14,692
11,745 (80)
6,113
1,401
40
48.0
3,327
2,756 (82.8)
1,779
669
40
35.4
10,782
8,549 (79.3)
4,111
1,229
34
51.9
* Culture confirmed cases with a MIRU-VNTR profile with at least 23 complete loci
** Calculated using the n-1 method (number of cases in a cluster-number of clusters/number of cases with a strain type)
$ The number of cases in England, Wales and Northern Ireland is higher than the sum UK-born and non UK-born as 583 cases have
unknown UK-born information
‡ Number of clusters with at least one UK-born person in the cluster
§ Number of clusters with at least one non UK-born person in the cluster
Source: Enhanced Tuberculosis Surveillance (ETS)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
28
Tuberculosis in the UK: 2013 report
4. TB treatment outcomes, UK, 2001-2011
29
Tuberculosis in the UK: 2013 report
Table 4.1: Treatment outcome at 12 months for
tuberculosis cases, UK, 2011*
Treatment outcome
n
%
7,302
82.9
Died
434
4.9
Lost to follow-up
435
4.9
Still on treatment
289
3.3
88
1.0
257
2.9
100
Completed
Stopped
Not evaluated
Total
8,805
* Excludes MDR-TB and RMP-resistant TB cases. Not evaluated includes missing, unknown
and transferred out
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 4.1: Trends in tuberculosis treatment outcomes at
12 months post start of treatment, UK*
100
90
2007
2008
80
Proportion of cases (%)
2009
70
2010
2011
60
50
40
30
20
10
0
Completed
Died
Lost to f ollowup
Still on
treatment
Stopped
Not completed, Not evaluated
reason
unknown
Outcome
*Cases who developed MDR or rifampicin resistance while on treatment were not available for years prior to 2010 and will remain in
the 12 month treatment outcome cohort for these years. These data were also not available for Scotland.
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Figure 4.2: Proportion of cases completing treatment by
Country and PHE Centre, UK, 2011
100
90
Percentage of cases
80
70
60
50
40
30
20
10
0
Country/PHE centre
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
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Tuberculosis in the UK: 2013 report
Table 4.1: Relationship between tuberculosis diagnosis and
cause of death at 12 months, UK, 2011
Relationship between TB and death
n
%
TB caused death
63
14.5
TB contributed to death
123
28.3
TB incidental to death
109
25.1
Unknown
139
32.0
Total
434
100
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
33
Tuberculosis in the UK: 2013 report
Figure 4.3: Treatment outcomes at 12 months for
tuberculosis cases by place of birth, UK, 2011
100
90
Non UK-born
80
Proportion of cases (%)
UK-born
70
60
50
40
30
20
10
0
Completed
Died
Lost to f ollow-up
Still on
treatment
Stopped
Outcome
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
34
Annual report on tuberculosis surveillance in the UK 2013
Not evaluated
Figure 4.4: Treatment outcomes at 12 months for
tuberculosis cases with at least one social risk factor, UK,
2011
90
80
90
No known social risk f actor
80
Known
socialsocial
risk frisk
actor
f actor
No known
70
Known social risk f actor
60
50
40
30
20
10
0
Percentage of cases
Proportion of cases (%)
70
60
50
40
30
20
10
0
Completed
Completed
Died Died Lost to
f ollow-up
Still Still
on treatment
on treatment
to f ollow-up
Lost
Outcome
Outcome
Stopped
Stopped
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
35
Annual report on tuberculosis surveillance in the UK 2013
Not
evaluated
Notevaluated
Figure 4.5: Treatment outcomes at 12 months for
tuberculosis cases with previous history of TB, UK, 2011
90
No previous history of TB
80
Previous history of TB
Proportion of cases (%)
70
60
50
40
30
20
10
0
Completed
Died
Lost to f ollow-up Still on treatment
Outcome
Stopped
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
36
Annual report on tuberculosis surveillance in the UK 2013
Not evaluated
Table 4.3: Treatment outcome at 24 months for MDR and
rifampicin resistant tuberculosis cases, UK, 2010
Treatment outcome
n
%
Completed
49
72.1
Died
0
0.0
Lost to follow-up
6
8.8
Still on treatment
7
10.3
Stopped
4
5.9
Not completed, no reason
1
1.5
Not evaluated
1
1.5
Total
68
100
Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI)
Data as at July 2013
Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England
37
Annual report on tuberculosis surveillance in the UK 2013