Transcript Document
Chapter 12
The Heart
Location, Size, and
Position of the Heart
In mediastinum
2/3 to the left of the body midline
Apex = point
Most inferior portion
Shape and size of a closed fist
Septum divides right and left sides
(internally)
Pericardium
Two-layered fibrous sac
Inner layer = visceral pericardium or epicardium
Outer layer = parietal pericardium
Pericardial cavity is filled with pericardial fluid
Approximately 15-30 ml pericardial fluid present
Three layers of the Heart Wall
Epicardium
Outer layer
Connective tissue
Myocardium
Middle layer
Thick
Muscle
Endocardium
Inner layer (lining)
Very thin, smooth
Summary of layers
Outside (external) to Inside (internal)
Parietal Pericardium
Pericardial cavity (filled with fluid)
Visceral Pericardium/Epicardium
Myocardium
Endocardium
Anatomy of the Heart
Heart chambers
Two upper chambers are
Right and left atria (atrium)
Small chambers
Receive blood
Two lower chambers called ventricles
Right and left ventricles
Larger chambers
Pump blood out of heart
Vessels
Pulmonary Arteries
Carry blood from R ventricle to lungs
R pulmonary artery to R lung
L pulmonary artery to L lung
Pulmonary Veins
Carry blood from lungs to L atria
R pulmonary veins from R lung
L pulmonary veins from L lung
Vessels cont.
Vena Cava
Inferior and superior
Empties blood into heart from body
Valves
Cuspid valves
Tricuspid: between right atrium and ventricle
Bicuspid (mitral): between left atrium and ventricle
Open and close from chordae tendineae
Semilunar valves
Pulmonary Semilunar: base of pulmonary arteries
Aortic Semilunar: base of aorta
Open and close from pressure within heart
The 4 valves
The heart is where
pulmonary
circulation starts
and ends.
The valves support
1-way movement
through the heart.
The heart
acts as two
pumps
Right atrium and
ventricle pump
deoxygenated
blood to the lungs
Left atrium and
ventricle pump
oxygenated blood
to the body
Sequence of
Blood Flow
Heart Sounds
Two distinct heart sounds in every heartbeat or
cycle—“lubb-dupp”
First (lubb) sound is caused by the vibration and
closure of AV valves during contraction of the
ventricles
Second (dupp) sound is caused by the closure of
the semilunar valves during relaxation of the
ventricles
Heart Actions
Contraction is called systole
Relaxation is called diastole
These actions create Blood Pressure
Practical Application
Supposed an individual was injured by falling off a
roof and he severely damaged his right arm with
copious blood loss. His blood pressure steadily
dropped to dangerous levels. How would you
explain the drop in his blood pressure?
Continued
In response to the drop in blood pressure, the heart
begins beating more rapidly. The increase in HR
increases overall blood flow and thus causes even
more rapid blood loss from a wound. The more
blood lost, the faster the heart beats and the faster
blood volume is lost. How can you explain this?
What type of feedback is this?
Cardiac Cycle
Heart beat is regular and rhythmic—each complete
beat called a cardiac cycle—average is about 72
beats per minute
Each cycle, about 0.8 seconds long, subdivided into
systole (contraction phase) and diastole (relaxation
phase)
Cardiac Cycle
Stroke volume is the volume of blood ejected from
one ventricle with each beat
Cardiac output is amount of blood that one
ventricle can pump each minute—average is about
5 L per minute at rest
Benefit of exercise!
Conduction System of the Heart
SA (sinoatrial) node
The pacemaker
In wall of right atrium near superior vena cava
AV (atrioventricular) node
AV bundle (bundle of His)
In the floor of right atrium near septum
Located in the septum of the ventricle
Purkinje fibers—
Located in the walls of the ventricles
Cause contraction of myocardium
Conduction System of the Heart
Electrocardiography
Measures the electrical impulses that result in contraction of
the heart
Impulses transformed into visible tracings by a machine called
an electrocardiograph
The visible tracing of these electrical signals is called an
electrocardiogram or ECG
Conduction System of the Heart
The normal ECG has three deflections or waves called the P
wave, the QRS complex, and the T wave
P wave—associated with depolarization of the atria
QRS
complex—associated with depolarization of the
ventricles
T wave—associated with repolarization of the ventricles
Issues with the heart’s conduction system
Bradycardia—slow heart rate (under 60 beats/min)
Tachycardia—rapid heart rate (over 100 beats/min)
Sinus dysrhythmia—variation in heart rate during breathing
cycle
Premature contraction (extrasystole)—contraction that occurs
sooner than expected in a normal rhythm
Fibrillation—condition in which cardiac muscle fibers are “out
of step,” producing no effective pumping action
Chronic diseases of the heart
Coronary Circulation and Coronary Heart
Disease
Blood, which supplies oxygen and nutrients to the
myocardium of the heart, flows through the right and
left coronary arteries
Blockage of blood flow through the coronary arteries
can cause myocardial infarction
CHD
Atherosclerosis (type of “hardening of arteries” in
which lipids build up on the inside wall of blood
vessels) can partially or totally block coronary blood
flow
Angina pectoris—chest pain caused by inadequate
oxygen to the heart
Heart Failure
Heart failure—inability to pump enough returned
blood to sustain life; it can be caused by many
different heart diseases
Right-sided heart failure—failure of the right side of
the heart to pump blood, usually because the left side
of the heart is not pumping effectively
Heart Failure
Left-sided heart failure (congestive heart failure)—
inability of the left ventricle to pump effectively,
resulting in congestion of the systemic and
pulmonary circulations
Diseased hearts can be replaced by donated living
hearts (transplants) or by artificial hearts (implants),
although both procedures have yet to be perfected