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100 100 100 100 100 100 200 200 200 200 200 200 300 300 300 300 300 300 400 400 400 400 400 400 500 500 500 500 500 500 What is Brugada Syndrome? What is Wolf Parkinson White Syndrome? What is Pericarditis? What is Wenckebach Phenomenon? What is Electrical Alternans (in pericardial effusion)? What is Herpes Zoster? What is Erythema Multiforme? What is Xanthelasma? What is Discoid Lupus Erythematosis? What is Bullous Pemphigoid? Diabetes mellitus associated with hypertrophic cirrhosis of the liver and dark brownish skin pigmentation caused by deposition of excess of melanin or iron pigment, or both, in tissues. What is Troisier's syndrome (TroisierHanot-Chauffard syndrome) ? A disorder mainly affecting postmenopausal women, marked by diabetes mellitus and hirsutims, deep masculine voice, facial hypertrichosis, obesity, hypertrophy of the clitoris, and hypoplasia or adenoma of the adrenal cortex. What is Achard-Thiers syndrome? A neurological phenomenon in which one or both pupils is dilated and responds slowly or not at all to light and a near stimulus, accompanied by slow constriction and relaxation in the change from near to distant vision, and impaired accommodation. What is Adie’s pupil (Adie's syndrome)? The development of renal dysfunction in patients with severe liver disease (acute or chronic) in the absence of any other identifiable causes of renal pathology. What is Frerichs' syndrome (Heyd's syndrome)? Not commonly used term for bronchopulmonary diseases occurring with aspiration of gastric juice. What is Mendelson's syndrome? HUTCHISON'S TEETH INTERSTITIAL KERATITIS NERVE DEAFNESS What is Hutchinson’s Triad? RECURRENT ORAL ULCERS GENITAL ULCERS IRIDOCYCLITIS What is Bechet’s Syndrome? GALL STONES DIVERTICULOSIS HIATUS HERNIA What is Saint’s Triad? CONDUCTIVE DEAFNESS IMMOBILITY OF HOMOLATERAL SOFT PALATE TRIGEMINAL NEURALGIA What is Trotter’s Triad? SIXTH CRANIAL N. PALSY PERSISTANT EAR DISCHARGE DEEP SEATED RETRO ORBITAL PAIN What is Gradenigo’s triad? What is Megaloblastic Anemia? What is Plasmodium falciparum Malaria? What are HowellJolly Bodies? What is Hairy-cell Leukemia? What is Mycosis fungoides Sezary cell? Staining pattern on ANA, relatively specific and sensitive for CREST. What is Anticentromere autoantibody? Not specific but sensitive for druginduced LE. What is Antihistone autoantibody? Seen in > 90% with active Wegener’s Granulomatosis. What is c-ANCA? By definition present in MCTD. What is U1RNP autoantibody? Can diagnose RA early especially when RF is negative. What is anti-cyclic citrullinated peptide antibody (anti-CCP)? 200 200 200 200 200 200 400 400 400 400 400 400 600 600 600 600 600 600 800 800 800 800 800 800 1000 1000 1000 1000 1000 1000 What is diabetic retinopathy? venous beading, hemorrhages, cotton-wool spots, intraretinal vascular abnormalities (IRMA), but most important neovascularization of the disc. What is papilledema? What is Optic atrophy? What is CMV Retinitis? What is Bergmeister’s Papilla? Ipsilateral oculomotor palsy and contralateral hemiparesis. What is Weber’s Syndrome? (hemiparesis alternans oculomotoria) Ipsilateral facial paresis, abducent paresis, horizontal gaze paralysis and contralateral hemiparesis. What is Foville’s Syndrome? Ipsilateral paresis of trapezius and sternocleidomastoideus and contralateral hemipareisis. What is Schmidt’s Syndrome? (hemiparesis alternans accessoria) Ipsilateral facial hemispasm and contralateral hemiparesis. What is Brissaud-Siccard syndrome? Ipsilateral oculomotor palsy and contralateral Hyperkinesis (athetosis, chorea) rigor and disturbance of deep sensibility. What is Benedikt’s Syndrome? A presystolic or late diastolic (mitral) heart murmur best heard at the apex of the heart. What is AustinFlint’s murmur? An early diastolic murmur like that of aortic insufficiency, heard best at the left lower central border in severe anaemia. What is CabotLocke murmur? Listen What is a split S1 (first heart sound)? •Conduction abnormalities: •right bundle branch block •pacing from an electrode on the LV •left ventricular ectopics •Mechanical causes: •Ebsteins anomaly •atrial septal defect •tricuspid stenosis Systolic and diastolic twophase murmur that can be heard over the femoral artery in severe aortic regurgitation when it is compressed with the bell of the stethoscope. What is Duroziez' murmur or sign? The increase in the intensity of the pansystolic murmur of tricuspid regurgitation during inspiration. What is Carvallo's sign? What is Halo Sign? In a cavity with fungus ball there is a crescentic lucent space along the upper portion of a density giving the appearance of a halo. This phenomenon is seen with two clinical presentations of pulmonary aspergillosis, fungous ball and necrotizing subacute pneumonia during recovery phase from leukopenic episodes. What is Bowing Sign? In LUL atelectasis or following resection, the oblique fissure bows forwards in the lateral view. Bowing sign refers to this feature. (A) Forward movement of left oblique fissure (C) Atelectatic LUL (B) Herniated lung from right. What are airbronchograms in right upper lobe consolidation? What is enlargement of the left hilum accompanied by left lung hyperlucency, indicating oligemia (Westermark's sign)? What is subpleural consolidation (Hampton's hump) in the right lower lobe, due to pulmonary infarction? Genes in inherited breast cancer. BRCA1 and BRCA2 Mutated gene location in adenomatous polyposis coli (Gardner’s syndrome). What is region 5q21-q22 on Chromosome 5? HLA association with ankylosing spondylitis. What is HLA-B27? What is the t(9;22) translocation or Philadelphia chromosome? What is the retinoblastoma gene? Located on the long arm of chromosome 13 (13q14). Best test to exclude irondeficiency anemia. What is serum ferritin? The best test to diagnose cystic fibrosis. What is the sweattest? The best way to screen for Cushing’s syndrome? What is a 24-hr urine collection for free cortisol, or an overnight 1 mg dexamethasone suppression test? The best test for excluding or confirming pheochromocytoma. What is measurement of plasma free metanephrines? Best treatment of this patient. What is thrombolysis or Primary PCI? What is lepromatous leprosy? Mycobacterium leprae.