Transcript OMX

OMX
In 1908, Ellie Metchnikoff a
nobel laureate working at the
Pasteur Institute, discovered
that ingestion of certain microorganism
can displace putrefactive toxinproducing bacteria… thus preventing
(and even treating) diseases,
thereby prolonging life and promoting
health…
(this was noted among Bulgarian farmers)
For the last 20 years, Dr.
Iichiroh Ohhira a Japanese
Microbiologist, awarded
Scientist of the Year in 1991
after successfully
encapsulating strains of
good bacteria as “Probiotics”.
is a LIVE microbial food
medicine which beneficially
improves and maintain human
intestinal microbial balance.
Definition by the FAO/WHO
“live microorganisms which when
consumed in ADEQUATE
AMOUNTS, confer a health effect
on the host.
profoundly disturbs the
intestinal ecosystem
(1)
(2)
(3)
References:
1. Colombe JF et al. Lancet. 1987
2. Vanderhoof JA et al. J Pediatr. 1999
3. Goodman & Gillman. Pharmacological Basis of Therapeutics
Effect of OMX capsule on Diarrhea in infants
3-24 months of age
JRRMMC
Design
Randomized controlled trial. (2 Capsules a day)
Outcome
Intake of OMX Probiotics capsule (1capsule BID for 5 days),
in addition to ORS, significantly reduced the duration of
Diarrhea in children compared with those who only received
ORS. The mean days Were shorter 3.17 days in the probiotic
Group than in the non-probiotic group with 5.42 days.
* Second Prize; PPS – Inter-subspecialty Convention
2006, Manila
Presented: 1st Asian Congress of Pediatric Research
Tokyo, Japan 2006
Effect of OMX capsule as Adjunct in the treatment of
Severe Pneumonia in infants 6-24 months Of age
JRRMMC
Design
Randomized controlled trial Group 1 ampicillin & probiotics
Group 2 probiotics only. (2 Capsules a day)
Outcome
Intake of OMX Probiotics capsule Significantly shortened the duration
of Illness (cough, fever, rales, retractions, Wheezing), hospital stay
and respiratory Symptoms with mean of 2.4 days in the Treatment
group vs. 4.3 days in the control Group. Increase of appetite was also
observed.
*First Prize; PPS – Inter-subspecialty Convention
2006, Manila
Presented: 3rd Asian Congress Pediatric Infectious
Disease, Bangkok, Thailand
2006
13th Pediatric Infectious Disease Society
of the Philippines, Cebu, 2006
Beneficial effects of probiotics, OMX capsule in
Grade II Dengue Hemorrhagic Fever
PCMC
Design
Randomized controlled trial Open label. (2 Capsules a day)
Outcome
Intake of OMX Probiotics capsule shows that patient did not
progress to further deterioration of their condition and were able to
have earlier normalization of their hematocrit and platelet count.
HCT 3.94 (control group) & 2.16 days (experimental group).
Platelet Count 5.50 (control group) & 3.3 Days (experimental
group).
Presented: 2nd Congress of Asian Pediatric Research,
Yokohama, Japan 2007
Effect of OMX Probiotic capsule on Immune
Markers of Undernourished Filipino Children
PCMC
Design
Randomized controlled trial Open label. (2 Capsules a day)
Outcome
Probiotics lead to significant weight gain (1 kilogram for
the first week) and shorter duration of infections.
Increase of appetite was also noted.
Presented: 25th International Congress of Pediatrics
Athens, Greece 2007
Effect of OMX, as adjunct treatment in Febrile
Neutropenia among children 2 – 18 years of age.
CSMC
Design
Double Blind Placebo Controlled Clinical Trial.
Outcome
OMX produced clinical reduction in mean body temperature,
shorter duration of hospital stay and significantly increase in
ANC count. Increase Appetite also was noted. With resolved
cases of UTI, mucositis and diarrhea.
* First Prize; 1.) CSMC Research Contest, 2008
2.) PSH&BT, September, 2008
Presented: Pediatric Academic Societies & 4th ASPR,
Honolulu, Hawaii, USA, 2009
OMX in the prevention of recurrent UTI in children
with Urinary Tract Abnormalities
PCMC
Design
Randomized Controlled Trial.
Outcome
OMX Probiotics prophylaxis was a s effective as
antibiotic prophylaxis in children with urinary tract
abnormalities; increase appetite was also noted.
* First Prize; 1.) PCMC - Research Contest, 2009
2.) PPS – Research Contest, April, 2009
Presented: Pediatric Academic Societies, 2009
Baltimore, Maryland, USA
POWDERS
(free powders and capsules)
The freeze drying process involves the removal of water
by subjecting the bacteria to extremes of heat and cold
and the application of vacuum. This drastic “ripping off”
of water from a living organism disrupts its structure,
function and internal environment.
•
•
•
•
•
•
•
Addition of stabilizers and preservatives prior to freeze drying.
Severe bacterial cell damage occurs if centrifugation and chemicals are used.
Extensive damage to bacteria caused by freeze drying process.
Powder shelf life is short.
Powder absorbs water, then bacteria become activated and die away.
Live bacteria in the powder have damaged walls and cannot grow properly.
Transport and storage is easier, but must be refrigerated.
LIQUID PREPARATIONS
(Yoghurt, etc.)
Liquid preparations offer major disadvantages which relate
to the instability of free organisms while in solution, harsh
methods of preparation such as pasteurization, and the
corrosive action of the stomach’s acid.
• Short shelf life (few organisms remain alive in solution after several weeks)
• Friendly bacteria damaged by pasteurization
(exposure to high temperatures 60 to 80 deg. C)
• Severe bacterial cell damage occurs if centrifugation and chemicals are used.
• Additives and preservatives are added to stabilize the bacteria in solution.
• Transport and storage is difficult.
• Not suitable for overseas travel.
FERMENTED PASTE
CONTAINING
FRIENDLY BACTERIA
The preparation of OM-X involves the use of natural
organic ingredients and a natural non-chemical
fermentation process unlike any other preparation
process currently used by industry.
- Bacteria-functional and viable.
- No damage to bacterial cell wall.
- No centrifugation.
- No freezing.
- Storage and transport is easy.
- No preservatives and additives.
If antibiotics were the
Medicine in the 20th century,
Probiotics will be the
Medicine in the 21st century.
“Don’t just save lives,
restore good health…”
“Let OHHIRA-OMX Probiotics
be your partner in care…”
Luisito L. Ruiz, M.D., FICS
Medical Director
South Star Drug
Mapagkakatiwalaang Tunay!
CAVITE
GENERICA PHARMACY