Transcript Chapter 18
Selected sections from Chapter 18
Cancer: Uncontrolled Cell Division and
Differentiation
Tumor
Benign
Malignant
Copyright © 2009 Pearson Education, Inc.
Characteristics of Benign Tumors and
Cancers
Copyright © 2009 Pearson Education, Inc.
Table 18.1
Tumors
Benign
Remain in one location
Single, well-defined mass
May be surrounded by connective tissue
Cancerous
Abnormal cell structure; may appear
undifferentiated
May spread
Edge of tumor not clearly defined
Copyright © 2009 Pearson Education, Inc.
Malignant Tumor Development
PLAY
Animation—Cancer
Copyright © 2009 Pearson Education, Inc.
Figure 18.2
How Cancer Develops
Apoptosis
Mutated or damaged genes
Proto-oncogenes
Normal regulatory genes
Oncogenes
Mutated or damaged proto-oncogenes
Tumor suppressor genes
Regulatory genes slow cell division,
TS genes may be turned off, damaged, or
mutated in cancers
Copyright © 2009 Pearson Education, Inc.
Factors Contributing to Cancer
Viruses and bacteria
Chemicals in the environment
Tobacco
Radiation
Dietary factors
Internal Factors
Free Radicals
Copyright © 2009 Pearson Education, Inc.
Cancer Treatments
Conventional treatments
Surgery
Radiation
Chemotherapy
Copyright © 2009 Pearson Education, Inc.
Ten Most Common Cancers
Copyright © 2009 Pearson Education, Inc.
Table 18.3
Most Cancers Are Preventable
Know family history
Get regular medical screenings
Learn self-examination techniques
Avoid direct sunlight 10 a.m. to 4 p.m.,
sunlamps, and tanning salons
Watch diet and weight
Don’t smoke
Drink in moderation, if at all
Be informed
Copyright © 2009 Pearson Education, Inc.