Transcript Quantification of velocity and tracking micron sized particles in 4.7T

Hari Prashanth
Research Advisors: Dr.Gregory Auner
Dr.Mark Haacke
Background
Under Grad :Electronics with specialization in:

Bio-instrumentation, Micro processors and micro controllers,
sensors and electronic devices
Masters: Electrical engineering

Image and signal processing, Magnetic resonance imaging
Research Interest: Flow imaging and quantification
techniques
Project involved: To quantify velocity in a –U- tube
and track the path of Escherichia coli (E-coli)
bacteria in water flowing in the –U- tube
Use of Phase contrast MRA to quantify
velocity through the –U-tube
42 in
Mean percent error for the measured flow
rates was found to 4.35% at the Inlet and
5.18% at the Outlet
Effects of acceleration seen at the outlet
Inlet
Outlet
Phase map
Flow phantom
Miniscule particles (polystyrene beads) of the same size of bacteria
were used as a means to mimic the effect of bacteria
Susceptibility effects of the beads causes rapid signal loss
(dephasing effect)
Echo time 5ms
Reference image
Bead concentration-120microlitre
For a concentration of 120microlitre beads the SNR dropped by 54%
at echo time 5ms in the stationery frame
Next step..

Use of True FISP sequence to take snap shots of the
entire phantom (coronally) with a temporal resolution
of about 780ms-1.5s per frame after injecting the
beads
Short term Career goal:

To gain more knowledge and hone my skills in the
field of MRI with respect to fast flow imaging
techniques and Image and signal processing domain,
either industrially or academically