Transcript Cells

Cells
Cell
• Definition
• 1. The structural, functional and biological unit of all organisms.
• 2. An autonomous self-replicating unit that may exist as
functional independent unit of life (as in the case of unicellular
organism), or as sub-unit in a multicellular organism (such as in
plants and animals) that is specialized into carrying out particular
functions towards the cause of the organism as a whole.
• 3. A membrane bound structure containing biomolecules, such
as nucleic acids, proteins, and polysaccharides.
(Science: Cell Biology)
Eukaryotic and Prokaryotic
• Animals & Plants (as well as Protocists and many Algae) have
cells that contain membrane bound organelles:
nucleus, mitochondria, chloroplasts etc.
• These are Eukaryotes
• Karyote from Greek karyon
(meaning kernal or nucleus)
Eu- meaning true
• Prokaryotes do not have these internal membranes
(Pro- meaning before)
Eukaryotic Cells
Organelles you need to know:
• Nucleus
– Chromatin
– Nuclear envelope
– Nucleolus
• Mitochondria
• Endoplasmic reticulum
Rough and smooth
• Ribosomes
• Golgi Body
• Lysosomes
• Centrioles
• Chloroplasts
• Vacuoles
• Plasmodesmata
Nucleus
• Largest Organelle (10-20μm)
• Double membrane contains pores (nuclear
envelope)
• Contains nucleic acids and proteins
• When not dividing, DNA bonded to protein
forming chromatin
• Nucleolus dense area, produces ribosomes
Mitochondria
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Rod like structures (1μm wide x 10μm long)
Powerhouse of the cell
Undertake Respiration
Produce ATP
• Symbiotic evolution
Centrioles
• Usually a pair
• Near the nucleus
• Involved in cell division
Endoplasmic Reticulum
• Network of cavities
bound by membranes
• Transport system
• Synthesis of chemicals
• RER – ribosomes,
protein
synthesis/transport
• SER - synthesis of
steroids and lipids
Ribosomes
• Small at ~20nm
• Made of a combination
of RNA and Protein
(65%:35%)
• Involved in protein
synthesis
• DNARNAProtein
Golgi Body
• Took ages for science to
discover what this did
• Used radioactive tracers
• Proteins transported there in
vesicles, fuse and pass thru’
• Proteins altered
(carbohydrates added etc.)
• Put into vesicles which bud
off
Lysosomes
• Digestive enzymes
packaged into a vescicle
• Fuse with food vacuoles
taken in by endocytosis
by single celled animals
or with damaged
organelles
• Can rupture and destroy
the whole cell apoptosis
Chloroplasts
• Large 4-10μm x 2-3 μm
• Chlorophyll
• Photosynthesis
Vacuoles
• Any fluid filled, membrane bound, space
• Animal cells have temporary ones
• Plant cells vac. is surrounded by a membrane
called the tonoplast
• Filled with cell sap
• Osmosis keeps it ‘inflated’
Plasmodesmata
Cytoskeleton
• 3D, “web-like” structure filling the cytoplasm
• Microfilaments (protein fibres)
• Microtubules (protein tubes 20nm diameter)
• Gives cytoplasm structure
• Holds organelles in place
• Linked to:
cell movements
transport
Prokaryotes
Bacteria
 Cause diseases
 good bacteria
 very very small (0.5 uM to 1 um in size)
1 cm
.
1 mm
1 uM (a bacteria)
Rod shaped
Coccus shaped (round)
‘BAD’ bacteria – cause diseases
 meningitis
Bacteria
 tuberculosis
(E. coli)
 anthrax
 the plague
 gonorrhoea
 diarrhoea and vomiting
Human intestinal cell
Bacteria ‘FIGHT’ with the human cells and immune system
to survive and cause disease
syphilis
gangrene
leprosy
Stomach ulcers
Tooth decay
plague
Escherichia coli (E. coli)
 Rod shaped bacteria
 causes vomiting and diarrhoea
 can cause kidney failure and DEATH
E. coli 1
E. coli 2
E. coli 3
E. coli 4
E. coli
flagella
Outer
membrane
Cell wall
Glycogen
granule
Plasma
membrane
Lipid droplet
ribosome
Circular
chromosome
flagella
Outer
membrane
Cell wall
Plasma
membrane
Glycogen
granule
Lipid
droplet
ribosome
Circular
chromosome
Viruses
Viruses
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Smallest of the microorganisms
0.002 – 0.3 µm (50x smaller than bacteria)
Viruses are not cells
Merely arrangements of genetic material and
protein
Electron
Micrographs
of Viruses
A. Bacteriophage T4
B. Potato virus X
C. Adenovirus
D. Influenza virus
Structure of viruses
• Viruses are geometric in shape
• Considerable variation in the genetic
material they have, structure of their
protein coat (capsid) or whether they
have an envelope
Cellular Organisation
Cells  Tissues
• Cells (basic units)
– Organisms either unicellular or multi-cellular
• Aggregations of Cells
– Colonies show little co-ordination
– More complex organisms show specialisation
– If perform similar function organised into tissues
Tissues
• 4 main types in the human:
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Epithelial tissues (lining of surfaces)
Connective tissue
Muscle tissue
Nervous tissue
Tissues  Organs
• Organs are made up of a group of tissues
together in one structure so that they can work
effectively.
Plant leaf as an Organ
Tissues:
• Epidermal
• Palisade mesophyll
• Spongy mesophyll
• Vascular tissue
(inc. phloem and xylem
tissues)
Organs  Systems
• When a number of organs work together to
carry out a large scale function it is known as a
system.