Transcript Document

Chapter 108: Periodontal
Diseases and Oral Bone Loss
Keith L. Kirkwood
Table 1. General Classification of
Periodontal Diseases and Conditions*
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
Table 2. Diagnosis of Periodontal Diseases
© 2008 American Society for Bone and Mineral Research
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
Table 3. Nonsurgical Treatment of Periodontitis
© 2008 American Society for Bone and Mineral Research
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
Table 4. Surgical Treatment of Periodontitis
© 2008 American Society for Bone and Mineral Research
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
Figure 1
Figure 1 Etiology of periodontal disease progression and factors that impact the disease progression.
Periodontal diseases can occur when periodontal pathogenic bacteria is present in a susceptible host.
Genetic and environmental factors modify the host immune response toward bacteria initiating tissue and
bone destruction manifested as periodontitis.
© 2008 American Society for Bone and Mineral Research
From the Primer on the Metabolic Bone Diseases
and Disorders of Mineral Metabolism, 7th Edition.
www.asbmrprimer.org
Figure 2
Figure 2 Anatomy of periodontal tissues and cellular biology of inflammatory bone loss. The periodontal
tissues surrounding the tooth include epithelium, connective tissue, periodontal ligament (PDL), and
alveolar bone. Inset depicts cell responses to bacterial plaque biofilm on the root surface.
Polymorphonuclear lymphocytes (PMNs) and macrophages (M) secrete inflammatory cytokines and matrix
metalloproteinases (MMPs) to increase the immune response and degrade connective tissue matrix.
Osteoclastogenesis is induced to these stimuli to increase bone resorption through RANKL/RANK system.
© 2008 American Society for Bone and Mineral Research