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Virulence Factors allow bacteria to cause
disease. They include:
•Attachment (via adhesins)
•Colonization
•Invasiveness
•Toxins & Enzymes
Virulence Factors
Invasiveness:
Hyaluronidase
Coagulase
Streptokinase
(dissolves Clots)
Membrane disrupting Toxins: e.g., hemolysins; leukocidin, phospholipase (removes charged head groups from phospholipids as is seen in
gas gangrene/Clostridium perfringens a-toxin
Classes of toxins
Neurotoxins
Enterotoxins
Cytotoxins