Transcript cell cycle and

CELL CYCLE
AND
CANCER
- Cell Division
Mitosis
• During mitosis, the cell’s nucleus divides
into two new nuclei. One copy of the DNA
is distributed into each of the two daughter
cells.
Cell Division
The -Cell
Cycle
- Cell Division
Length of the Cell Cycle
How long does it take for a
cell to go through one cell
cycle? It all depends on the
cell. A human liver cell, for
example, completes one
cell cycle in about 22
hours, as shown in the
graph. Study the graph and
then answer the following
questions.
- Cell Division
Length of the Cell Cycle
• Reading Graphs:
– What do the three
curved arrows
outside the circle
represent?
–The longest curved
arrow represents the
cell’s interphase; the
shortest represents
cytokinesis; and the
middle one represents
mitosis.
- Cell Division
Length of the Cell Cycle
• Reading Graphs:
• In what stage of
the cell cycle is
the wedge
representing
growth?
– Interphase
Length of the Cell Cycle
• Interpreting Data:
– In human liver
cells, how long
does it take DNA
replication to
occur?
–10 hours
- Cell Division
Length of the Cell Cycle
• Drawing
Conclusions:
– In human liver
cells, what stage
in the cell cycle
takes the longest
time?
– Interphase
- Cell Division
Structure of DNA
• The DNA molecule is shaped like a twisted
ladder.
• How do the Nitrogen bases pair up?
• Adenine – Thymine
• Cytosine - Guanine
• What is it?
- Cell Division
Replication of DNA
• When DNA make exact copy of itself
• Do the nitrogen bases have to match up?
• YES!!
• How?
• Adenine – Thymine
• Cytosine - Guanine
Sequencing
Can you name the stages and phases of
Cell Cycle?
Interphase
Cytokinesis
Cell grows, makes a
copy of DNA.
Mitosis:
Prophase
Chromosomes and
spindle fibers form;
nuclear envelope breaks
down.
Cell pinches in two; each
daughter cell has same number
of identical chromosomes.
The Cell Cycle
Chromosomes stretch out;
new nuclear envelope forms
around chromosomes.
Mitosis:
Telophase
Mitosis:
Anaphase
Centromeres split;
chromatids separate and
move to opposite ends.
Chromosomes line up
across the center and
attach to a spindle fiber.
Mitosis:
Metaphase
What Is Cancer?
• Let’s find out
• You will work in groups of 3
• Each group member will learn and then teach
specific information about Cancer
to the other team mates!
• 1st member will teach: WHAT IS CANCER
• 2nd member: TREATING CANCER
• 3rd member: CANCER PREVENTION
• Each member will take notes
• Finally everyone will have to answer 3 specific
questions – we will review them!!
- Cancer
What Is Cancer?