Transcript Document

Practice of Endoscopic Mucosal
Resection: A Survey to Endoscopic
Units in Europe
Class 15 – FMUP – 2008/2009
19th December 2008
André Carvalho, Ana Morais, Clara Ferreira, Francisco Mourão, João Santos, José
Martins, Mariana Formigo, Manuel Cruz, Raquel Santos
Mário Dinis-Ribeiro, Ricardo Santos
BACKGROUND
Gastric Cancer:
-Steady decline on the incidence 1
vs
- High rates of death by recurrence and
progression of the disease 1
Spread on the scientific interest
Roukos DH. Current advances and changes in treatment strategy may improve survival and quality of life in patients with potentially curable
gastric cancer; Academic Department of Surgery, Medical School, University of Ioannina, Greece Ann Surg Oncol. 1999 Jan-Feb;6(1):46-56;
1
BACKGROUND
Detection
Stage of development
Early stage
Advanced stage
Different approaches on
the treatment
BACKGROUND
• EMR and ESD – an answer !
Japan, 1980  described in 1984
• Early gastric cancer
(mucosa/submucosa)
• Alternative to surgery!
BACKGROUND
Advantages2:
•Less morbidity
Better
•Less mortality
quality of life
•Less invasive
•Posterior histological analysis
•Allows posterior surgery
Disadvantages3:
• High incidence of complications
•Requires high endoscopy skills
Ahmadi A, Draganov; Endoscopic mucosal resection in the upper gastrointestinal tract. P. Division Gastroenterology Hepatology and
Nutrition, University of Florida, Gainesville, Florida 32610, United States World J Gastroenterol. 2008 Apr 7;14(13):1984-9
2
Tanaka M, Ono H, Hasuike N; Endoscopic submucosal dissection of early gastric cancer; Takizawa K.Division of Endoscopy and
Gastrointestinal Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan
3
JUSTIFICATION
• In Europe:
•<10 % of all endoscopically diagnosed gastric
cancers are in an earlier stage of
development 4
• In Japan:
•50 % of all endoscopically diagnosed gastric
cancers are in an earlier stage of
development 4
4 Roukos
DH. Current advances and changes in treatment strategy may improve survival and quality of life in patients with potentially curable
gastric cancer; Academic Department of Surgery, Medical School, University of Ioannina, Greece Ann Surg Oncol. 1999 Jan-Feb;6(1):46-56;
RESEARCH QUESTION
What is the current use of
endoscopic resection
techniques (EMR/ESD) in
european centers?
STUDY DESIGN
- Observational study
- cross-sectional study
-
PARTICIPANTS
Target population
European endoscopic units/centers
Sampling method:
Non-random:
 Members of the national societies of endoscopy
 European centers that published papers indexed in
Pubmed during 2007 and 2008 in:
Gastrointestinal Endoscopy journal
 Endoscopy journal
DATA COLLECTION AND VARIABLES
• Online questionnaires regarding the following
variables:
• Number and tipe of procedures
• Completeness of procedure
• Complications
• Type of lesions
• Number and expertise of operators
• Questionnaire will be completed and used by the
participants using Medquest, developed on SBIMFMUP.
GANTT CHART
GANTT CHART
GANTT CHART
Expected results
• Final product: paper with the results of the study
- Earlier perspectives:
- Small rates of usage
- Non application due to the inexistence of enough
knowledge of the techniques