cell cycle and cancer 2016x

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Transcript cell cycle and cancer 2016x

Tuesday – 10/25
• On your warm-up sheet of paper from
yesterday, complete the following:
Describe the various stages of the life cycle of a
human being from beginning to end.
Cell Cycle vs. Life Cycle
The cell cycle is similar to the life cycle of a
human in that they both have various phases
that are associated with distinct characteristics.
Cell Cycle Video
• As you watch the video clip below, try and list
the phases of cell growth and division that
are mentioned in the video.
• Record your answer below your warm-up.
https://www.youtube.com/watch?v=VRhz3DhjG5M
Cell Cycle Notes
Using your diagram, fill out the blanks to the
best of your ability using the word bank.
Fill in the blank
• The purpose of mitosis is for growth and division of cells
• As a cells get bigger, in interphase (G1) it,
– Uses up more oxygen and glucose more quickly
– Places more demand on its DNA
– Has more trouble transporting enough material across its
membrane
• The cell then replicates its DNA (S phase) which mean it
makes an identical copy or synthesis of DNA
• The next phase G2 is preparation for mitosis, which
means copying of organelles and growing even more to
prepare for mitosis
• Cell division consists of 2 parts
– Mitosis – 4 phases that divides the nucleus
– Cytokinesis – the division of cytoplasm and the cell
membrane
Mitosis Hands
• Lets learn mitosis hands.
• On the back of your warm-up, number 1-6 on
the left-hand side of your paper.
• Leave some room between each number.
• Write the name of each phase and the
defining characteristics of each phase.
– Be sure to focus on the genetic material.
Spinner!
Line up your Circle Cut Out
with the Full page notes
side with the pictures.
Carefully use your brad to
poke a hole through both
pages to create your
spinner!
Wednesday: 10/26
• Use your spinner notes that you made yesterday
to answer the following:
1. Which phase of the cycle is the
longest? What 3 events make up
this phase?
2. List the order of events of the cell
cycle, starting with G1.
3. What is the purpose of mitosis?
Let’s Practice!
• For each picture, write the following things on
your notebook paper.
• Use your spinner to help you!
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. Metaphase
2. Lined up in the middle
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. Interphase
2. No defined chromosomes
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. Telophase
2. Daughter cells are
pulling apart from
each other, but not
completely
separated.
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. Prophase
2. Chromosomes are
formed (looks like
worms)
1. The phase the cell is in.
2. The defining
characteristic of that
phase.
3. Draw a picture
1. Anaphase
2. Chromosomes are
pulling away.
(Opposite sides of
the cell)
Take a minute to look over your notes
about the phases of the cell cycle
below. Memorize them. Be able to
label this. You will be questioned on
this…
On a notebook sheet of paper, put the pictures
in order (draw your own pictures) and write the
name/description of each phase
Check our Answers!!!
Below are plant cells in various stages of the cell cycle.
On a sheet of paper, number 1-18. Describe what phase the cell is in,
and write a brief description of what is occurring in this phase. Start
with the numbers that have lightening bolts, and then complete as
many as you can. You have 5 minutes to finish as much as you can.
Complete the questions with a star by them.
Prophase
2
10
Spindle fibers
Cytokinesis
S phase
centromere
chromatids
23
2
daughter
Cell plate
prophase
centrioles
metaphase
Sister
chromatids
anaphase
centromere
telophase
Spindel
fibers
C
B
E
A
D
Exit Ticket
• Try and list the phases of the cell cycle in order
(including the steps of mitosis).
• Describe each phase in as much detail as
possible.
• When you finish, flip it over on your desk.
Friday – 10/28
• WITOUT USING YOUR NOTES, Fill in the wheel
I provided you at the door with as much
information as you can remember.
WHAT IS
CANCER?
1. HOW MANY TYPES OF CANCER
DO YOU THINK THERE ARE?
Sample
text
There are over 200 types
of cancer
COMMON CANCERS
*
*Includes malignant brain and central nervous system tumours.
WHICH CAUSES OF CANCER CAN
YOU CONTROL?
WHICH CAUSES OF CANCER CAN
YOU CONTROL?
Sample
text
Sample
text
2. Cancer is generally a disease of...
A. Older age
B. Childhood
C. Middle age
Sample
text
3. How does cancer develop?
A. You can catch it from someone
B. When cells divide out of control
C. From a blood transfusion
Sample
text
Refresher: How many
types of cancer are
there?
A. 20
B. 200
C. 2000
Name the 4 most
common cancers in
the UK
• Breast
• Lung
• Prostate
• Bowel
QUIZ
4.TRUE
TRUE OR FALSE?
There
are many
things
A healthy
lifestyle
isn’t a
within
our control
guarantee
againstthat
cancer,
can
reduce
the
risk
buthelp
it can
help to
stack
ofthe
cancer...
odds in your favour
5. TRUE OR FALSE?
TRUE
It is possible to inherit genes from your
But this doesn’t necessarily mean you
parents that make you more likely to
will get cancer. It just means you’re at
develop a certain type of cancer?
higher risk
QUIZ
Sample
text
6.TRUE
TRUE OR FALSE?
Cell
a natural
Butdivision
if it getsisout
of
process,
for the
control,needed
cancer can
growth,
developrepair and
replacement of cells in
the body...
QUIZ
TRUE
Being active is a
7. TRUE
great
wayOR
toFALSE?
help
Being physically
reduce
the risk of
active
can
reduce
bowel, breast and
the risk
of cancer...
womb
cancers.
Aim for about 60
minutes a day
Cancer Reading
• As you read through the passage, underline or
highlight the key info using the dry erase
marker.
• Then, using the info in the passage, fill out the
graphic organizer to the best of your ability.
Cancer Notes
• Write any additional notes on the back of your
graphic organizer over the next 2 slides.
Disruptions
• Disruptions in mitosis can lead to diseases such as cancer.
• Cells contain internal and external regulators. Internal regulators
allow the cell cycle to proceed only when certain processes have
occurred (ex. all chromosomes have been replicated)
• Cancer is an uncontrolled synthesis of cells. If a mutation occurs in
the genes that control the cell cycle, then mitosis could occur
before the cell has gone through the all stages of interphase or
even if the cell has been damaged.
• Example: The p53 gene product normally senses DNA damage and
either halts the cell cycle until it can be repaired or, if the damage
is too massive; triggers apoptosis. Apoptosis is programmed cell
death.
Cancer Cells Clip
(1:07)
Cancer Cell Clip 2
(2:53)
Exit Ticket
• Clear everything off your desk except for
something to write with.
• Fill out the cell cycle with as much information
as you can remember.
• When you finish your exit ticket, flip it over on
your desk.
Monday – 10/31
• Grab your binder as you come in.
• Complete your warm-up on your warm-up
sheet from last week.
Using complete sentences, describe how cell
division of cancerous cells is different than cell
division of healthy cells.
Roll The Dice Game
1. One person in the group will roll the dice.
2. That one person will answer the question on the
next slide for the number you roll.
3. You will pass the dice to the person on your left,
they will roll and answer the question they
landed on.
4. Keep repeating until all questions have been
answered. It is ok if someone else answers the
same question that’s been answered before.
1. What is the
purpose of cell
division?
2. What phases
make up just
mitosis?
3. Describe how DNA
can look during the
cell cycle.
4. List all the
phases of the cell
cycle in order.
5. Describe how
cancer forms.
6. Explain what
all occurs during
Interphase
Bingo
• Take all of your notes off your desk.
• Fill out the phase of the cell cycle, or specific
phase of mitosis, that corresponds with the
description on the screen.
Card Sort
• Place the cards with the various phases of
mitosis in the correct order.
• Try and do this without your notes, but if you
get stuck, you may use your notes.
Jeopardy
https://jeopardylabs.com/play/the-cell-cycle3
Mitosis Practice
• Fill out the half-sheet by labeling the stages of
mitosis.
• Try and do this without your notes, but if you
get stuck, you may use your notes.
Exit Ticket
• Clear everything off your desk except for
something to write with.
• Fill out the cell cycle with as much information
as you can remember.
• When you finish your exit ticket, flip it over on
your desk.
Friday – 10/30
TEST DAY!
Take 5 minutes to study your notes and ask me
any last minute questions.