Transcript Epigenetics Question

Epigenetics Questions E-Lab!
Directions
• In your notebooks on p. 51-54* answer the following
questions for each module.
• Please do this in order from module 1-5
• Complete all questions during this lab period
• Watch the corresponding videos for each module if
provided
• Play around with the simulations to help your responses to
these questions
• Do copy questions: answer in complete sentences and
name each module for each set of questions!!! 
• *if you need the extra room
Link
• http://learn.genetics.utah.edu/content/epige
netics/
Pages 51-54
• Module 1: Epigenome at a Glance
– 1. describe the physical state of the
genome (tightly wrapped or relaxed) when
genes are inactive
– 2. describe the physical state of the
genome (tightly wrapped or relaxed) when
genes are active
P. 51-54 (do not copy the same set of questions
twice, just answer in a complete sentence)
• Module 2: Gene control
– 1. Describe the following characteristics when gene is
ACTIVE
•
•
•
•
Is the gene tightly or loosely wrapped around histones?
Are there many or few acetyl molecules attached to the gene?
Are there many or few acetyl molecules attached to the histones?
Are there many or few mRNA transcripts?
– 2. Describe the following characteristics when gene is
INACTIVE
•
•
•
•
Is the gene tightly or loosely wrapped around histones?
Are there many or few methyl molecules attached to the gene?
Are there many or few methyl molecules attached to the histones?
Are there many or few mRNA transcripts?
p. 51-54
• Module 3: Insight on Identical Twins
*note* watch twin video first
• 1. often the physical characteristics of
identical twins becomes different as they age.
Explain why this is so. ( use terms like
environment and epigenome) complete
sentences
• 2. name 3-4 environmental factors that
influence the epigenome.
p. 51-54
• Module 4: Lick your Rats!
• 1. explain how a high nurturing mother rat
shapes her pup’s epigenome, and what that
pup’s response to stress will be. Complete
sentences.
• 2. In rats, does the mother’s licking
activate or deactivate her pup’s GR gene?
• 3. relate this activity to humans and think
about personal and social implications.
Write your thoughts in complete sentences
(min 2-3)
p. 51-54
• Module 5: Nutrition and Epigenome
1. Explain how food we eat affects gene
expression. Complete sentences.
2.Can diets of parents affect their
offspring’s epigenome? Explain how.
Complete sentences.
P.51-54
• Conclusion
• 1. Explain what epigenetics is using
academic vocabulary (use your vocab lists!)
• 2. Describe and elaborate on how the
environment/lifestyle affects your
genes.
• 3. How do you think your lifestyle affects
your epigenome?