Transcript Introduction

Welcome to IB 201!
Genetics and Evolution
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Instructors
Lecture
Teaching Assistants
Dr. Kim Hughes
Moni Berg
(Genetics)
Karen Cavey
Dr. Sydney Cameron
Casey Funderburk
(Evolution)
Beth Ruedi
Laboratory
Dr. Kevin Dixon
Required Texts
Selected Chapters from “Essential
Genetics”, by Russell, available online
“Evolutionary Biology”,
by Freeman and Herron
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Other reading material will be distributed
in class or available on the course web
site.
How to access the chapters
of the Genetics text online
Go to www.coursecompass.com. Once there
you should register as a student. Enter your
code to register and create a login and
password.
Once you are logged in select IB 201 under the
courses option.
Select “Biology Chapters” from the side menu.
Scroll down until you get to “Genetics
Appendix”.
6 chapters from the Genetics text (by Russell).
You can download them and either view them
on your computer or print them out.
Course Web Site
http://www.life.uiuc.edu/ib/201
Class schedule
Assigned readings
Homework assignments
Lecture notes
Powerpoint slides
Recommended problens
Course Pre-requisites
IB 150: Organismal and Evolutionary
Biology
MCB 150: Molecular and Cellular Basis of
Life
Review material available on the course
web site: Basic Mendelian and
Molecular Genetics
Grading
Lecture: 70% of grade; Laboratory: 30%
Lecture: 700 points total:
Two Midterms: 75 points each
Final Exam (cumulative): 100 points
Six Homework assignments: 75 pts ea
Online multiple-choice assignments:
access them from the course web site.
Extra Credit
Questions at beginning of class
Based on reading assignment
Answer due before class starts
2 pts each class (one-half letter grade)
Course Policies
NO MAKEUP EXAMS
HW assignments posted on the course
web site, due before 9:00 am on due
date. No extensions
Final: 1:30-4:30 pm Friday, May 6, in this
room
Course Policies
NO MAKEUP EXAMS
HW assignments posted on the course
web site, due before 9:00 am on due
date. No extensions
Final: 1:30-4:30 pm Friday, May 6, in this
room
How to succeed in this course
Come to class!
Read the assigned material before class
Download lecture notes before class.
Bring a calculator and scrap paper to
class.
Do recommended problems: you will
see them again!
Participate in class discussion
Don’t
Furiously take notes during class
Put off the homework until the last
minute
Put off doing recommended problems
until just before the exam
IB 201 Genetics and Evolution
Part 1 Genetics
Dr. Kim Hughes
465B Morrill Hall
[email protected]
Office hours: Tu/Th after class or by
appointment
Practice Quiz
1. Round-seeded pea was crossed to a wrinkle-seeded pea
all the offspring were round. Diagram the cross and
predict the ratio of wrinkled to round offspring in the F2
generation.
2. A round-seeded pea is crossed to a wrinkle-seeded pea.
Half the offspring are round and half are wrinkled. What
are the genotypes of the parents, the round F1 offspring,
and the wrinkled F1 offspring?
3. True-breeding yellow, round plants were crossed to true
breeding green, wrinkled ones. All F1 offspring are yellow
and round. What are the genotypes of the parents and
the F1 offspring? What phenotypes, and in what
proportions, do you expect in the F2 generation?
4. A red snapdragon is crossed to a white snapdragon and all
the offspring are pink. This is an example of what genetic
property?
Practice Quiz
5. A woman homozygous for the A allele of the ABO blood
group marries a man who is homozygous for the B
locus. What is the blood group phenotype of their
child? This is an example of what genetic property?
6. What is the most likely mode of inheritance illustrated by
this pedigree?
7. The combined probability of two or more mutually
exclusive events occurring is the ________ of their
individual probabilities.
8. The joint probability of both of two independent events
occurring is the _________ of their individual
probabilities.
Terms you should know
Gene
Locus
Allele
Dominance
Recessiveness
Wild type
Mutation
Genotype
Phenotype
Homozygote
Heterozygote
Monohybrid
Dihybrid
Pleiotropy
Epistasis
Autosome
Sex chromosome
Hemizygous
Pleiotropy
Epistasis
Haploid
Diploid
Nuclear DNA
Mitochondrial DNA
Chloroplast DNA
Chromosome
Homologous
chromosomes
Sister chromatids
Tetrad
Mitosis
Meoisis
Independent
assortment
Recombination
Crossing over
Transcription
Translation
Answers
1.
2.
3.
4.
5.
6.
7.
8.
P: WW x ww
F1: Ww
F2: 3/4 round (W-) to 1/4 wrinkled (ww)
P: Ww x ww
F1: 1/2 Ww (round) and 1/2 ww (wrinkled)
P: GG WW x gg ww
F1: Gg Ww
F2: 9/16 yellow, round (G- W-); 3/16 yellow, wrinkled (G- ww);
3/16 green, round (gg W-); 1/4 green, wrinkled (gg ww)
Incomplete dominance
AB; Codominance
X-linked recessive
Sum (this is the “sum rule” or the “addition rule” of probability
Product (this is the “product rule of probability)
If you found these questions easy
You’re prepared to start this class
If these questions were not easy
You should attend the review session and
study review material
Review session: Today, 5 pm,
140 Burrill Hall