Transcript BioInfo
Introduction to Oral Cancer Gene Database ．資訊三 朱民晃 B92902025 ．資訊三 陳皓遠 B92902062 The Tumor Gene Family Databases Introduction(1/2) • http://www.tumor-gene.org/ • The Tumor Gene Family of Databases contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. • These databases are designed to for biomedical researchers who work with tumor genes. Introduction(2/2) • Tumor Gene Database • Breast Cancer Gene Database • Oral Cancer Gene Database Oral Cancer Gene Database • What information dose the database contain? • This database contains information about genes which are targets for cancercausing mutations in oral cancers. • List of Oral Cancer Genes • A member of the Tumor Gene Database family • http://www.tumor-gene.org/Oral/oral.html Get the list of Oral Cancer Genes (1/2) Click here to get information of the Oral cancer list Get the list of Oral Cancer Genes (2/2) • List of Oral Cancer Genes How to search the database (1/4) Key in a Gene Name or a word in a fact you want to search How to search the database (2/4) Click the “Search” button to search How to search the database (3/4) Get 1 match of the gene “BAX” Click the hyperlink of “BAX” How to search the database (4/4) OMIM ID Number of NCBI OMIM ID Number What can we get ? (1/2) • Cell Type Distribution • Clinical • Complementation • Function • Gene Frequency (Tumors) • Protein Binding • Regulation What can we get ? (2/2) Link to Citation of NCBI Flag Flags Primary Fact from a Full Paper Primary Fact from an Abstract Secondary Fact from a Full Paper Secondary Fact from an Abstract Primary Fact from a Review Secondary Fact from a Review Unknown Link to GeneCards (1/2) Click here to link to GeneCards website Link to GeneCards (2/2) NCBI – OMIM (1/4) Remember to choose “OMIM” *600040 , the OMIM ID Number NCBI – OMIM (2/4) Click here; go to the OMIM homepage. Click “FAQ” to get details about OMIM NCBI – OMIM (3/4) What do the symbols preceding a MIM number represent? NCBI – OMIM (4/4) Ex: An asterisk (*) before an entry number indicates a gene of known sequence. Conclusion • We can search the information about oral gene in the database. • We can get the OMIM ID about the gene in the NCBI database. • We can get the list of genes in the oral database. • We can link to GeneCards website. Thanks for your attention.