Transcript Slide 1
The Work of Gregor
Mendel
Genetics
• Heredity – transmission of traits from one
generation to the next
• Genetics – study of heredity
Gregor Mendel’s Peas
• Augustinian monk named Gregor Mendel in
1800s worked with peas to demonstrate the
basic genetic principles we know today
• Mendel’s garden peas were true-breeding,
meaning that if they were allowed to selfpollinate, they would produce offspring identical
to themselves
• Mendel selected the pea plants that he would
breed with each other.
• Why pea plants?
– Easy to care for, grow quickly, take up little space, etc
Genes and Dominance
• Mendel studied several different pea plant traits
• Trait – specific characteristic, such as seed color or plant height, that
varies from one individual to another
• Each trait Mendel studied had two contrasting characters – Ex. Seed
color – yellow or green
Flower
Color
Pod
Shape
Pod
Color
Smooth
Green
Seed
Shape
Seed
Color
Round
Yellow
Wrinkled
Green
White
Constricted
Round
Yellow
Purple
Smooth
Purple
Flower
Position
Plant
Height
Axial
Tall
Yellow
Terminal
Short
Green
Axial
Tall
Genes and Dominance
(continued)
• Mendel crossed plants with each of the
contrasting characters and studied their
offspring
• Each original pair of plants were the P (parental)
generation. The offspring from the cross were
called the F1 generation
• Offspring of crosses between parents with
different traits are called hybrids
• F1 generation of pea plants had the character of
only ONE of the parents. The other character
seemed to have disappeared…
Genes and Dominance
(continued)
• Mendel then came to a few hypotheses:
– There are alternative versions of genes (Mendel
termed genes “factors) that account for variations in
inherited characters (different versions of a gene =
alleles)
– An organism inherits two alleles - one allele from
each parent – homozygous (same
alleles)/heterozygous (different alleles)
– Principle of Dominance – some alleles are dominant
and others are recessive
– (the fourth we’ll talk about in a moment)
Principle of Dominance
• Dominant allele – an organism with a
dominant allele for a particular form of a
trait will always have that form (Ex. Aa, AA
= dominance)
• Recessive allele – an organism with a
recessive allele for a particular trait will
only have that form when the dominant
allele isn’t present (Ex. aa = recessive)
Law of Segregation
– Mendel wanted to know what happened to the
recessive traits that seemed to have
disappeared
– Crossed F1 plants with themselves to produce
F2 (second generation) plants – this caused
the recessive traits to reappear
– Roughly 1/4th of the F2 plants showed the
recessive trait
Segregation
(continued)
– Reappearance indicated that at some point,
the recessive allele separated from the
dominant allele = Segregation
– Fourth Hypothesis: Law of Segregation - Two
alleles are segregated from each other so that
each gamete (sex cell – sperm or egg) carries
only a single copy of each gene
Example: Tallness vs. Shortness in
Pea Plants
P generation cross (true breeding)
TT
(tall)
x
x
tt
(short)
F1 generation
Tt
(all tall plants produced)
F1 generation cross (self-pollinated)
Tt
(tall)
x
x
Tt
(tall)
F2 generation
TT, Tt, Tt, tt
(3 tall, 1 short plant produced)
Principle of Dominance
P Generation
Tall
Go to
Section:
Short
F1 Generation
Tall
Tall
F2 Generation
Tall
Tall
Tall
Short
Principle of Dominance
P Generation
Tall
Go to
Section:
Short
F1 Generation
Tall
Tall
F2 Generation
Tall
Tall
Tall
Short
Principle of Dominance
P Generation
Tall
Go to
Section:
Short
F1 Generation
Tall
Tall
F2 Generation
Tall
Tall
Tall
Short
Gregor Mendel’s Work
Gregor
Mendel
concluded
that
experimented
with
Pea
plants
“Factors”
determine
traits
Some alleles
are dominant,
and some alleles
are recessive
which is
called the
Law of
Dominance
Alleles are
separated during
gamete formation
which is
called the
Law of
Segregation