Transcript Slide 1

Genetic Repositories Australia
BACKGROUND
 GRA supported by an NHMRC Enabling Facility Grant awarded in 2006.
 Chief Investigators on the NHMRC Enabling Grant are –
Professor Peter Schofield (Prince of Wales Medical Research Institute &
University of New South Wales)
 Dr Juleen Cavanaugh (Australian National University, Medical School, Canberra
Hospital)
 Dr Susan Forrest (Australian Genome Research Facility)
Professor John Hopper (Centre for Genetic Epidemiology University of
Melbourne)
 GRA is based at the Prince of Wales Medical Research Institute in Sydney.
 Facility Manager is Mr Steve Turner.
GRA - Aims and Objectives

GRA aims to provide a central national facility for –
• establishing
• distributing and
• maintaining the long-term secure storage of human genetic
samples from a variety of sources.

GRA aims to facilitate world-class collaborative health and medical
research in Australia, and internationally through:
 the provision of clinically validated but de-identified patient
material
complete phenotypic descriptors of disease and family, or cohort
structure
permits genetic analyses for disease gene identification.
GRA - Services

A central facility for the processing of blood samples and production
of B-lymphoblastoid cell lines.

Extraction of DNA from blood or cell lines.
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Samples will be processed from patients, controls and
epidemiological participants from studies on a range of diseases and
their outcomes.
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DNA and immortalized cell lines will be stored for distribution to
qualified investigators.

Samples available for distribution will be processed at a subsidised
academic rate.

Fee-for-service work can be performed for samples not available for
distribution.
GRA
FURTHER INFORMATION
Mr Steve Turner, Facility Manager (GRA)
Prince of Wales Medical Research Institute
Randwick, Sydney,
Email: [email protected]
Telephone: (+ 61 2) 9399 1068
Website: www.powmri.edu.au/gra.htm
The ARCBS Aussie Normals
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1000 ARCBS blood donors – healthy Caucasians
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Cell lines & DNA
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DNA available in 96 well plates from mid April
2007
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Biochemical phenotype available via
collaboration with researchers (Cavanaugh &
Hickman @ ANU)
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Projects subject to approval by ARCBS
AGRF Services
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SNP Discovery
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Genotyping
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Expression analysis