Transcript PowerPoint
How Cells Release Chemical Energy
Photosynthesis
Light energy converted into stored energy
(glucose)
CO2 + H2O => C6H12O6 (glucose) + O2
Endergonic
Cellular
Respiration
Stored energy (glucose) converted into useable
energy (ATP)
C6H12O6 (glucose) + O2 => CO2 + H2O
Exergonic
Aerobic
Respiration
Requires oxygen
High energy (ATP) yield
Glycolysis—cytoplasm
Kreb’s Cycle—mitochondrial matrix
Electron Transport System—cristae
Anaerobic
Respiration
Doesn’t require oxygen
Organisms without mitochondria
Low energy yield
Step
1—Glycolysis
Glucose (6C) broken down into two PGAL (3C)
PGAL restructured into pyruvate
Produces 2 NADH
Requires 2 ATP to start
Produces 4 ATP
Net gain of 2 ATP
Glucose
P-Glucose 2 Pyruvate
Step
2a—Acetyl-CoA
Pyruvate (3C) combines with CoA
Releases CO2
NAD+ NADH
Forms acetyle-CoA (2C)
2 Pyruvate => 2 CO2 + 2 NADH
Step
2b—Krebs Cycle
2 Acetyl-CoA enter
Transfers carbons to oxaloacetate (C4), forming
citrate (C6)
Cycles through steps to rearrange citrate
2 CO2 released
Ends forming oxaloacetate
Cycle starts again
Net gain of 4 CO2, 6 NADH, 2 FADH2, 2 ATP
Step
3—Electron Transfer Phosphorylation
NADH & FADH2 from previous steps start chain
Electrons flow through “chain” of membrane
proteins
Each protein then takes H+ from above molecules
and pumps them into intermembrane space
This sets up concentration gradient
H+ moves down gradient through ATP synthase
Movement forms ATP from ADP & P (32 net gain)
Ends with electrons passed to O2, combines with
H+ to form H2O
If
no oxygen, electrons can’t pass on
This backs up to NADPH, so no H+ gradients
No ATP forms, starving cells
Glycolysis
Glucose + 2ATP 4ATP + 2NADH + 2 Pyruvate
Intermediate
2 Pyruvate 2CO2 + 2NADH + 2 Acetyl-CoA
Krebs
Cycle
2 Acetyl-CoA 6NADH + 2ATP + 2FADH2
Electron
Transfer
10NADH + 2FADH2 32ATP + 4CO2 + 6H2O
C6H12O6
+ 6O2 6H2O + 6CO2 + 36 ATP + heat
Fermenters
Protists, bacteria
Marshes, bogs, deep sea, animal gut, sewage,
canned food
Some
die when exposed to O2
Some indifferent to O2
Some can use O2, but switch to fermentation
when none around
Glycolysis
happens normally
2 Pyruvate, 2 NADH, 2 Net ATP form
Enough energy for many single-celled species
Not enough energy for large organisms
Glucose
2 Pyruvate 2 Acetaldehyde + 2
CO2
NADH + Acetaldehyde Ethanol
Yeasts
Bread
Beer
Wine
Glucose
Pyruvate Lactate
Can
spoil food
Some bacteria create food
Cheese, yogurt, buttermilk
Cure meats
Pickle some fruits & vegetables
Muscle
Slow-twitch—light, steady, prolonged activity
cells
Marathons, bird migrations
Many mitochondria
Only aerobic respiration
“dark” meat in birds
Fast-twitch—immediate, intense energy
Weight lifting, sprinting
Few mitochondria
Lactate fermentation
Produce ATP quickly, but not for long
“white” meat in birds
Glucose
absorbed
through intestines
When glucose level
rises, glucose
converted to
glycogen
Diverts at glucose-6phosphate in
glycolysis
Glycogen
is storage polysaccharide
Stores in liver & muscles
With low blood glucose, insulin released
This triggers glycogen to convert back to
glucose
If too many carbohydrates/glucose in blood,
acetyl-CoA diverted & made into fatty acid
Body
stores most fats as triglycerides
When glucose levels fall, triglycerides used
Enzymes remove glycerol
Glycerol
converted
to PGAL
PGAL converted to
pyruvate as in
glycolysis
Happens
when eat too many proteins, or
when carbohydrates & fats used
Enzymes break down protein molecules
Ammonia (NH3) removed
Leftover carbon backbone split
Forms acetyl-CoA, pyruvate, or intermediate of
Krebs cycle
Specific amino acid determines which is formed