Transcript Functional replacement of DL

TM
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
Formulation
lab study
 DL- Methionine price fluctuation
 Cost effect protein source
 Natural replacer
 Methionine price and monopoly
THE NEED
Field trials
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
Formulation
lab study
Field trials
November 2009
Amino acids are available and synthesized in all living forms, the order of importance of the
same would differ. Thus, essential amino acids for one category of life can be a non essential
and easily synthesized in vivo by another organism
Thus,
• Replacing DL-Methionine by a source of natural origin??
• Functional replacement of DL- Methionine ??
• Improving digestibility of rations for better methionine assimilation ??
• Using precursors of Methionine and enzyme systems for in vivo biotransformation??
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
January 2010
Comparable products in market
Pricing placement of product
Efficacy reports from known sources
Complete market analysis to justify product development
Formulation
lab study
Field trials
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
Formulation
lab study
Field trials
March 2010
Research compilation and analysis for various international and domestic published papers
Narrowing down of selective known functional roles
Study of precursors and enzyme pathways
Study of analogues
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
Formulation
lab study
Field trials
November 2010
Herbal options from known sources
Natural ingredients mimicking functions of methionine
Precursors in plants
Herbs and natural substances improving digestibility of methionine from common livestock
diets
Use of sulfur donors and methyl donors in natural forms
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
January 2011
Combination of selected ingredients ,stability, and interaction
Amino acid content of these formulations
Dosage and DL-Methionine comparison of dosage
Formulation
lab study
Field trials
Technical Milestones
Conceptualization
Market
analysis
Methionine
study
Ingredient
study
2011 to 2015
Trials,
Lab scale to field scale to probable customer trials
Total trials conducted – 12
Lab scale - 2
Field scale – 9
Probable customer trial - 2
Formulation
lab study
Field trials
TM
KIFAY is a DL-methionine replacer of natural origin. It improves the availability of
essential amino acid methionine and has a methionine sparing effect on the body.
KIFAY helps regulate all functions of methionine in the body. It is a combination of
various herbs rich in sulfur entities and source of methionine complementing active
bio-constituents.
TM
APPLICATION,MECHANISM OF
ACTION AND USPs
KIFAY - Mechanism of action
Improves amino acid digestibility of ingredients.
SAMe rich fractions give methionine sparing effect and reduces the methionine requirement
Functional replacers in the formulation compensate and surpass performance of DL-Methionine
as a growth promoter and immunomodulant.
Plants rich in cofactor Vitamin B12 which is important methionine uptake and metabolism.
Intestinal microbiodata modulation to improve methionine uptake and nitrogen recycling.
Application of KIFAY -steps
Formulate least cost matrix ( All parameter set)
Calculate DL-Methionine required/Recommended
Replace 75 % of DL-Methionine by KIFAY
Replace Mass by Mass of KIFAY for DL-Methionine.
All replacement are independent of final proximate analysis including total crude protein levels
Application of KIFAY –steps, eg.
•
CP – 23 %, Typical energy – 3200 ME/Kg
Calculate DL-Methionine required/Recommended
•
Methionine - 0.5 % , 5 Kg per ton of feed
Replace 75 % of DL-Methionine by KIFAY
•
3.75 kg of DLM replace by 3.75 Kg of KIFAY
•
Final diet will have 3.75 Kg KIFAY + 1.25
Kg DLM
Formulate least cost matrix ( All parameter set)
Replace Mass by Mass of KIFAY for DL-Methionine.
All replacement are independent of final proximate
analysis including total crude protein levels
USPs
Least cost formulation
Maximum profitability even from adding less protein in diet , thus
reducing the cost by improving bioavailability of amino acids.
Inherent hepatoprotectant effect in the formulation
Natural and effective DLM replacer
Dosage
 Calculate total methionine requirement per ton of feed per phase( Prestarter, starter, grower and finisher separately)
 Replace 75 percent of artificial methionine by KIFAY
75:25
TM
A product of
VINAYAK INGREDIENTS (INDIA) PRIVATE LIMITED
Corporate Address :
Unit No.116, 1st Floor, Cama Industrials Estate,
Sunmill Compound Lower Parel - West,
Mumbai - 400 013. INDIA.
Tel : +91 22 40560400
Facsimile - +91 – 22 - 40560404
mail : [email protected]
www.vinayakcorporation.com