Transcript Protein Synthesis Animation

Protein Synthesis:
to ______ proteins
3
Protein Synthesis Cartoon
2
Purple Petunia
http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html
Purple Petunia Follow Up Questions
1. What did the scientist want to do to the petunia?
Why?
2. What happened to the petunia? Why?
3. What analogy is used for DNA?
4. What analogy is used for mRNA?
5. What analogy is used for the ribosome?
6. What does RNAi stand for?
7. What disease is being studied using RNAi?
8. What analogy is used for a virus
9. What other disease might RNAi help to cure?
DNA vs. RNA
How are DNA & RNA
different?
7
Tools
• DNA
• RNA
o tRNA
o rRNA
o mRNA
o RNAi
• Amino Acids: building blocks of proteins (come from your
food)
• Enzymes
Steps of Protein Synthesis
4
Protein Synthesis Animation
1. Transcription: DNA is used to make mRNA
2. Translation: mRNA is used as the code for amino acid
sequence (protein)
Transcription
4 &7
Happens in the nucleus
1. Helicase unzips the DNA
2. RNA polyermase reads the DNA from 3' to 5'
3. RNA polymerase makes a mRNA (messenger RNA) in the 5'
to 3' direction (A, U, C, G)
4. mRNA leaves the nucleus through nuclear pore
Transcription
5
Translation
4
Happens in the ribosomes within in the cytoplasm
1. mRNA enters the rRNA and is matched with a tRNA
2. tRNA transfers the correct amino acid
3. after all the mRNA has tranferred throught the ribosome
Translation
6
Amino Acid Chart
8 &9
Codon codes for a specific amino acid (20 total)
Big Picture
1
Protein Synthesis Animation
Bibliography
1. "Protein Synthesis Learning Activity." Wisc Online. 02JUL. Wisc Online. 2 Jul 2009 <http://www.wisconline.com/objects/index_tj.asp?objID=AP1302>.
2. "RNAi." scienceNOW. 06JUL2009. PBS. 6 Jul 2009 <http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html>.
3 "MRNA-interaction.png." Wikipedia. 06JUL2009. Wikipedia. Web.6 Jul 2009.
<http://en.wikipedia.org/wiki/File:MRNA-interaction.png>.
4. "Protein Biosynthesis." Wikipedia. 2009. MediaWiki1.16alpha. Web.6 Jul 2009.
<http://en.wikipedia.org/wiki/Protein_biosynthesis>.
5. "Stem Cells." National Institute of Health. 23AUG2004. National Institute of Health. 6 Jul 2009
<http://stemcells.nih.gov/StaticResources/info/scireport/images/figurea6.jpg>.
6. "Lecture 12." Oregon State. 16SEP2005. Oregon State . 6 Jul 2009
<http://oregonstate.edu/instruction/bb331/lecture12/fi5p20.gif>.
7. "Translation." UCA. 16SEP2005. UCA . 6 Jul 2009
<http://images.google.com/imgres?imgurl=http://faculty.uca.edu/johnc/translation.gif&imgrefurl=http://faculty.uca.ed
u/johnc/rnaprot1440.htm&usg=__MGIIXHca8BhUzAqJZgASLZpW3aA=&h=522&w=375&sz=39&hl=en&start=1&
um=1&tbnid=MNocwIfF2UNznM:&tbnh=131&tbnw=94&prev=/images%3Fq%3Dprotein%2Bsynthesis%2Btranslat
ion%26hl%3Den%26client%3Dfirefox-a%26channel%3Ds%26rls%3Dorg.mozilla:enUS:official%26sa%3DG%26um%3D1>.
8. "image003." Bioephemera. 04MAY2007. Bioephemera.com. 7 Jul 2009 <http://bioephemera.com/wpcontent/uploads/2007/03/image003.jpg>.
9. "image007." CHSTeachers. 28JAN2005. CHS. 7 Jul 2009
<http://www.ccs.k12.in.us/chsTeachers/BYost/Biology%20Notes/translation_files/image007.jpg>.