Transcript haruan spray for burn and wound

HARUAN SPRAY FOR BURN AND
WOUND
Prof. Saringat bin Bai @ Baie
School of Pharmaceutical Sciences
Universiti Sains Malaysia
Minden 11800
Penang, Malaysia
BACKGROUND
Haruan fish contains a lot of amino
acids and fatty acids  important to
improve wound healing process
• At this moment , there are two types of
Haruan preparation in the market to improve
wound healing.
PROBLEM STATEMENT
• Wound care films in the market:
- have limited size and singly packed  can’t cover
different sizes of wound
- easily contaminated
- difficult to use at certain part of body
• Majority of dressings for wound such as:
 plasters
 bandages
cause pain during dressing
 Dressing pads
and removal process
traumatic dressing
SOLUTION
Haruan Spray
combination between a comfortable dressing
for dermal wound and to provide an adequate
nutrition to the wound site
NOVELTY AND USEFULNESS
• Can cover any size of wound
• Ease of application and removal (water
washable)
• Can protect the wound
• Can heal the wound faster
• Can replace skin graft
• Product remain sterile
COMPETING PRODUCT
•
•
-
In spray dressing form:
OpSite
Nobecutane
In film dressing form:
Tegaderm
Omiderm
Bioclusive
Dermafilm
Etc.
COMMERCIALIZATION POTENTIAL
• Have an agreement with Major Interest
Sdn.Bhd. to manufacture and marketing
the product
• Market target: can be distributed to all
over the world
RESEARCH FUND
• RU Grant of USM
- 1 in 2007 : Formulation
- 2 in 2009 : Wound healing test and Stability
study
• TechnoFund
• Innofund
IMPACT OF THE PRODUCT
• Increase human’s health for better quality of
life
• Reduce the cost for patient’s ward at hospital
after surgery
• As an alternative for diabetic wound
treatment
ACADEMIC RECOGNITION
• Poster and oral presentation: 9
• As invited speaker: 1
• Published Journal: 3
Image at 0h
Image at 2.5h
Image at 5h
Image at 24h
Effect of haruan aqueous extract in migration of mouse fibroblast cells
Image at 0h
Image at 5 h
Image at 2.5h
Image at 24h
Effect of haruan aqueous extract in migration of human foreskin fibroblast cells
Irritation study of Haruan Spray in abraded and non abraded skin
Day 0
Day 3
Day 6
Day 9
Day 12
Pictures of incision wound healing at day 0, 3, 6, 9, and 12
Untreated
Blank
P1
P2
Day 3
Day 6
Day 15
Day 21
Photographs of burn wound at day 3, 6, 15 and 21 for control group (untreated),
treated with blank, P1 (treated with haruan), P2 (treated with haruan+fusidic
acid)
A
C
B
D
Photographs of histology study of burn wound treated with (A) blank, (B)
haruan, (C) haruan+ fusidic acid, (D) untreated on day 7 (magnification
100x)
A
B
C
D
Photographs of histology study of burn wound treated with (A) blank, (B)
haruan, (C) haruan+ fusidic acid, (D) untreated on day 14 (magnification
100x)
55 year old diabetic
women got infected
hand, operated and
treated with CSKIN
FIX cured after one
month.
50 year old male diabetic patient, injured
his leg and had gangrene to one of his
finger, operated and treated with
CSKINFIX , cure after one month. (1st
Photo, two weeks in hospital, no
improvement, 3rd Photo after one month
treatment)
Won Silver Medal In 39th Geneva
International Invention,6-9 April 2011