Transcript Hyoscyamus niger

Drugs acting on Nervous
system
Hyoscyamus
Objectives
On completion of this period you would be able
to learn about the
Monograph of the CNS Drug
HYOSCYAMUS
Known to Unknown
1.
Have you seen Datura plant in your collage campus?
2.
To which family it belongs to ?
3.
Can you give other example of Solanaceae drug?
4.
Does Hyoscyamus belongs to Solanaceae ?
HYOSCYAMUS
Syn: Henbane
• Biological Source:
It consists of dried leaves or
flowering tops of
Hyoscyamus niger
Family : Solanaceae
• Geographical Source:
It is a native of West Asia,
North Africa, Europe and India.
Also cultivated in Russia, Belgium
and Hungary
Fig.29.1
Cultivation And Collection
• Done in temperate at an altitude of 2400-3300m
• Seeds are sown in small seed beds and seedling are
raised
• Seedlings are transplanted in fields in May by keeping a
distance of half meter
• Leaves are collected when the plant is flowering
• Leaves are carefully dried
Morphological Characters
LEAF
• Size
: Length – 25cm
• Shape : Ovate
• Apex
: Acute
• Base
: Symmetrical
Fig.29.2
Morphological Characters
LEAF
• Margin : Triangularly dentate
• Surface : Hairy
• Colour : Pale greyish green
• Odour
: Characteristic & strong odour
• Taste
: Acrid
Fig.29.3
Chemical Constituents
• Total alkaloidal content is 0.05 - 0.15%
• In which 75% is Hyoscyamine
• Atropine and Hyoscine are present in small amounts
Uses
• Antispasmodic and Antiasthmatic
• Used to relieve spasm of urinary tract
• Administered with strong Purgatives to prevent gripping
• Has weak Parasympatholytic action
• Sedative and used to check Salivary secretion
Allied Drugs
• Hyoscyamus albus
Grown in France and India
• Hyoscyamus muticus
Grown in Egypt and India
Summary
In this class we discussed about
•
CNS plant drug – HYOSCYAMUS
•
Its Biological Source, Morphology, Chemical
Constituents, uses and allied drugs
Quiz
1.
The chief chemical constituents present in
Hyoscyamus are
a) Alkaloids
b) Glycosides
c) Latex
d) None of the above
Quiz
2. Hyoscyamus belongs to the family
a) Annonaceae
b) Leguminosae
c) Solanaceae
d) None of the above
Frequently Asked Questions
1.
Write the Botanical source and uses of Hyoscyamus
2.
Write the Morphological characters and Chemical
Constituents of Hyoscyamus