Transcript Prescr.. - TiECon Midwest 2016

Prescription Decision Support
For Primary Care
Kevin Mayes, CEO
October 2016
High Cholesterol
Acid Reflux
Poor
Metabolizer
• Lansoprazole
• Omeprazole
• Pantoprazole
Gene
CYP2C19
Extensive
Metabolizer
• Esomeprazole
• Rabeprazole
Commonly Prescribed
Pharmacogenomics (PGx)
Will this drug work?
Avoid expensive meds the
patient won’t respond to
How fast will it metabolize?
Calibrate effective dose
without trial and error
What side effects will occur?
Ensure patient compliance
and avoid serious events
Gap between promise and reality
98% of physicians believe genetics influence prescribing
only 13% are comfortable ordering a test
Why?
Knowledge Barriers
Use Case Barriers
1. 50-100 new research articles
published every week
1. Tests expensive, rarely
reimbursed
2. Difficulty understanding
clinical relevance of evidence
2. Decision made at point of care,
but tests take weeks
3. No way to interpret the
raw genetic information
3. No time to interpret complex
reports
Our Co-founders
• Discovered many drug-on-gene correlations
• Frustrated that PGx wasn’t translating to
clinical use
MARK RATAIN, M.D.
• Founded Center for Personalized Therapeutics at
University of Chicago
• Created the Genomic Prescribing System (GPS)
• 4+ years and $4MM in grants
• Rigorously tested “1,200 Patients Project”
• 20 physicians, 8 specialties, 4,000+ encounters to date
PETER H. O’DONNELL, M.D.
Research Backed Solution
• Study Results
• Clinical efficacy demonstrated in published
research
• ~90% patients had 1+ PGx drug
• Physician embraced
• 85% felt made better decision
• Market interest demonstrated by physicians
requesting to use GPS in their own practice
• PrescriptIQ founded to address market
demand
• Incubated at Polsky Center
• Study physicians among its launch customers
About Us
• SAAS-based clinical decision support software for primary care
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Gene-on drug interactions
Medication cost
Drug-on-drug interactions
Drug-on-drug-on-gene interactions
• Integrated into physician workflow via web-based interface & EMR
• Single, proprietary & preemptive genomic test provided by CLIA lab
Market Traction
• Early-adopter customers
• 2 concierge physician practices
• 2 large academic health systems (Stanford & UCSF)
• Searching for health system pilot
• International interest
• Singapore, Japan and China
• Seed round in progress ($450K of $650K raised)
• Building leadership team
• Goal: demonstrate evidence to achieve reimbursement
Thank you!
www.prescriptiq.com