Transcript New Treatments

New Treatments
Summary
New drug treatments
Chronotherapy
Lung cancer vaccine
New drug treatments
- Royal Marsden Hospital (London)
- Specific mutations
- Sophie (11y/o) → success
Chronotherapy
- Biological clock
- Circadian rhythms
- Signs + symptoms change
→ Chronotherapy
- Treatments at most optimal time
Chronotherapy
- Inconvenients:
-
Best time = night (often)
Mechanisms not well known
- P53 protein:
-
tumour suppressor
helps prevent mutation
- Personalised treatment
Lung cancer vaccine
Introduction
-
Center of Molecular Immunology
1st lung cancer vaccine
Cimavax
Not a cure:
survival of patient
- helps immune system
- therapeutic vaccine
-
Advantages
- Cheap to produce + store
- Few side effects
nausea
- chills
- fever
-
How does it work ?
Cancer stimulates production EGF
Stimulates growth of cells
Tumors multiply + grow uncontrollably
EGF : epidermal growth factor
→ body creates antibodies
Research
- Chemotherapy + ½ vaccine
- Trials showed:
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More antibodies
Lived longer
Reduces cancer symptoms
This vaccine could
be used for other
types of cancer
Conclusion
- A lot of new treatments
- More and more effective
- Cancer has to be found early
- However, treatments more effective on some
people than on others