Faculty of Pharmacy, University of Lisbon

Download Report

Transcript Faculty of Pharmacy, University of Lisbon

HOME/2014/JDRU/AG/DRUG/7086
Milan, 28th February-1st March 2016
1
FACULTY OF PHARMACY,
UNIVERSITY OF LISBON
One of the 18 schools and institutes from UL (since 2013), the
largest public academic higher education institution in Portugal;
Raking first among the Schools of Pharmacy in Portugal;
Is a highly-regarded
Pharmaceutical Sciences;
research-oriented
institution
in
Is the host institution of iMed.ULisboa, a multidisciplinary R&D
Unit in Life and Health Sciences.
Milan, 28th February-1st March 2016
2
INTEGRATED MASTER IN
PHARMACEUTICAL SCIENCES
Hospital
Pharmacy
Teaching &
Research
Regulation of
Medicinal Products
Integrated Masters
Students
1212
Pharmaceutical
Distribution
Community
Pharmacy
Milan, 28th February-1st March 2016
Pharmaceutical
Industry
Clinical
Analysis
Chemical, Biological
Hydrological,
Bromatological and
Toxicological Analysis
3
MASTER PROGRAMMES
Pharmaceutical
and Medicinal
Chemistry
Pharmaceutical
Intervention and
Therapeutical
Management
Quality
Control and
Food
Toxicology
Pharmaceutical
Engeneering
(in cooperation with
Técnico-ULisboa)
Regulation and
Assessment of
Medicinal Produ
cts
Herbal
Medicines
Pharmacotherapy and
Pharmacoepidemiology
Masters Students
170
Clinical
Analysis
Bio-pharmaceutical
Sciences
Milan, 28th February-1st March 2016
4
PHD PROGRAMME: IN MEDICINES AND
PHARMACEUTICAL INNOVATION (I3DU)
iMed.ULisboa Members
94
Integrated
Members
Total
277
Integrated
Members
94
PhD Students
121
Collaborators
PhD Students
121
121
PhD Students
62
Technicians &
Administrative
Staff
8
Other Trainees
Milan, 28th February-1st March 2016
61
5
RESOURCES & SERVICES
• Integrating the National Roadmap of Research Infrastructures
MS; NMR; Translational research (Health Cluster Portugal)
• Partnering within ESFRI
Instruct; EU OpenScreen; EATRIS
Milan, 28th February-1st March 2016
6
PROJECT: HOME/2014/JDRU/AG/DRUG/7086
FFUL AND EMCES TEAMS
Milan, 28th February-1st March 2016
7
TEAM FFUL (LEADER OF WS2)
NAME:
–
–
–
Dora Brites, Group Leader (Neuron-Glia Biology in Health and Disease)
Ana Sofia Falcão, PhD
Ana Rita Vaz, PhD
ACTIVITIES:
–
Neuroinflammation and neurotoxic mechanisms in neurodevelopmental diseases, neurodegenerative
disorders and ageing, including signaling cascades and target discovery
CAPABILITIES:
–
–
–
–
–
–
Cell Function/Dysfunction, Cell Biology and Histopathology
in vitro cultures (primary cultures and co-cultures in 2D and 3D systems
in-vivo models of Alzheimer´s disease and Amyotrophic lateral sclerosis
ex-vivo models (organotypic cultures)
Neuron-glia communication, exosome dissemination and microRNAs
iPSCs and neural derived cells
PAST EXPERIENCE:
–
–
–
–
Senior researcher at FFULisboa
Professor of Histology and Embriology and of Physiopathology of Neuroinflammation
Member of the Directive Board of the Doctoral Program in Integrative Neuroscience, Faculty of Medicine,
ULisboa
Member of the Coordinator Council and of the Executive Director of Mind-Brain College, ULisboa
Milan, 28th February-1st March 2016
8
TEAM FFUL (WS1 AND WS3)
NAME:
 Rui Moreira, Group Leader on Medicinal Chemistry,
Coordinator of Pharmaceutical and Therapeutical
Chemistry Department)
ACTIVITIES:
 Organic synthesis, Medicinal chemistry, metabolism
studies
CAPABILITIES:
 Laboratories for chemical synthesis, photoreactions,
metabolism studies and structural elucidation
PAST EXPERIENCE:
 Medicinal Chemistry, with a recent entry in the field of
drugs of abuse
Milan, 28th February-1st March 2016
9
TEAM FFUL (WS1 AND WS3)
NAME:
– Maria Bronze, Coordinator of Toxicological and Bromatological
Department
ACTIVITIES:
– Analytical Chemistry: implementation and validation of methods
CAPABILITIES:
– Sample preparation methodologies: SPE, SPME...
– Separative methodologies : gas and liquid chromatography
equipment with mass spectrometry
PAST EXPERIENCE:
– Analysis of compounds in different matrices (food, food wastes,
water, biological fluids)
Milan, 28th February-1st March 2016
10
TN EAM
FFUL
(WS1, 2, 3)
:
AME
– Cristina Sampayo
ACTIVITIES:
–
–
Pharmacology, safety and health effects of bioactive compounds in laboratory and target
animals, including behaviour and cognitive studies, pharmacodynamics and non-clinical PK
NC drug development as Expert member for evaluation of veterinary medicines (GAMV) and
Expert at the European Medicines Agency (EMA), including ERA of medicinal products
CAPABILITIES:
–
–
–
–
–
–
In vitro and ex-vivo models for drug transport studies, d.r.c studies and genotoxicity studies.
In vivo motor, behavioural & cognitive studies (ataxia, rota rod, SFT, W-M, T-M, Marble test,
Open field, Novel Object Recognition, Conditioned Place Preference tests in rodents)
In vivo models of skin, inflammation, metabolic and bone disorders (rodents)
FELASA Certificate Cat. C – Directing Animal Experiences (2010)
DIA certificate on Non-Clinical Safety Sciences and their Regulatory Aspects (2009)
EMA Assessors Training in ERA of Human Medicinal Products (2008)
PAST EXPERIENCE:
–
–
–
–
2007-…….. - Pharmacology Teaching & Pharmacotoxicology Teaching (Ms Pharmaceut. Sc., UL & UAL)
2003-2012 - Psychopharmacology Teaching (Ms Psychology, UL & INUAF)
2008-2012 - Environmental Risk Assessment of Human Medicines Teaching (Ms R. Affairs M&HP UL)
2004-2007 - Specialist on the evaluation of human medicines authorized by centralized (EMA)
and national procedures at Portuguese Medicines Agency, INFARMED, I.P.
11
Milan, 28th February-1st March 2016
TEAM FFUL (WS1 AND WS3)
NAME:
 Nuno Silva and Paulo Paixão
ACTIVITIES:
 Modelling and Simulation on Pharmacokinetics and
biopharmaceutics; Phase I clinical trials
CAPABILITIES:
 M&S, Software for QSAR and PBPK
PAST EXPERIENCE:
 medicinal products pharmacokinetics and clinical
trials
Milan, 28th February-1st March 2016
12