Transcript Predstavitev dr. Knezevica

Regenerativna medicinapriložnost za podjetja?
Miomir Knežević
Nacionalni inštitut za biologijo
www.nib.si
[email protected]
Uporabljeni material:
• Stem cells and the
innovation process
Global commercialisation
of UK stem cell research
Nicola Perrin:
[email protected]
– Dr Paul Martin
Ian Bunker:
– Institute for the Study [email protected]
of Genetics, Biorisks
and Society (IGBiS)
The Role of Technology Foresight in
• University of
Anticipating Global Technology Trend,
Nottingham, UK
Terutaka KUWAHARA, NISTEP
Ocene poslovnih
priložnosti
Embrionalne
matične
celice
Tkivno
inženirstvo
Ne moreš graditi ugleda na tistem, kar
šele nameravaš narediti
Henry Ford
Uporaba nanotehnologije
Zakasnitveni čas od tehnološke realizacije do uporabe
15
* Nuclear fusion energy area is
excluded.
Environmental and ecological biology
Nano devices and sensors
Regenerative medical science
Gap (years)
Innovative nuclear power systems
Clean-use technology
for fossil resources
10
NEMS
technology
Information/communications
Electronics
Life science
Basic
technology for
robotic and
manned space
activity
5
New information
and
communications
principles
Health/medicine/welfare
Agriculture, etc,
Frontier
Energy/resources
Environment
Nanotechnology/materials
Manufacturing
Industrial infrastructure
0
2005
2010
2015
2020
Time of technological realization
2025
2030
Social infrastructure
Social technology
Multidisciplinarno okolje – Vede o življenju postajajo center
2005- 2015
2015-2025
Nanotechnology
and material
ナノテク材料
Manufacturing
製造
Industrial
産業基盤
infrastructure
Electronics
エレクトロニクス
農林水産・食品
Agriculture,
forestry,
fisheries and food
Health, medical care
保健・医療・福祉
and welfare
Industrial
産業基盤
infrastructure
社会技術
Science
and
technology for
society
ライフサイエンス
Life sciences
Life
sciences
ライフサイエンス
環境
Environment
Environment
環境
Social 社会基盤
infrastructure
Health, medical care
保健・医療・福祉
and welfare
エネルギー資源
Energy and
resources
情報・通信
Information
and
communications
Science
and
社会技術
technology for
society
Electronics
エレクトロニクス
情報・通信
Information
and
communications
Nanotechnology
and material
ナノテク材料
Manufacturing
製造
Nanotechnology
and material
エネルギー資源
Energy
and
Agriculture, forestry,
fisheries
and food
農林水産・食品
resources
2015年までに
積極的に進めるべき融合・連携関係
Space,
marine
フロンティア
and
earth science
Space, marine
フロンティア
and earth science
社会基盤
Social infrastructure
2016-2025年までに
積極的に進めるべき融合・連携関係
（注1）各分野で融合・連携を進めるべき当該分野以外の分野を３つまで回答。
（注2）各分野で融合・連携を進めるべきと３割以上が回答した分野に向けて→を表示し、 双方が該当する場合は←→で表示。
（注3）赤太線は５割以上が、融合・連携が必要であると回答した領域間である。
*1 Respondents chose at most three fields to cooperate.
*2 Black arrow indicates that 30% to 50% of respondents.
*3 Red arrow indicates that more than 50% of respondents.
Po 2015
Sprememba vpliva “Ved o življenju”
Pred 2015
Technology for measuring
biological substances
Bioinfomatics
Nanobiology
Basic research for new
medical technologies
Index povečanja znanja
Basic research in
drug development
Brain generation and growth
Understanding and
treating brain conditions
Controlling higher-order
biological functions
Higher-order brain functions
Socialno-ekonomski pomen
Regenerative
medical science
Environmental
and ecological
biology
Predvideni čas realizacije tehnologij – Vede o
življenju
Čas uporabe v praksi
Čas tehnološke realizacije
2005 2010 2015 2020 2025 2030 2035
Bioinformatics
Information
biology
Controlling
higher-order
Controlling
higher-orderbiological
biological
functions functions
Basic
Basicresearch
researchin
indrug
drug development
development
Technology
forformeasuring
Technology
measuringbiological
biological
substances
substances
Environmental
Environmentaland
andecological
ecologicalbiology
biology
Nanobiology
Nanobiology
Regenerative
Regenerativemedical
medicalscience
science
Understanding and treating brain
9.0 yrs.
9.0 yrs.
10.8 yrs.
10.6 yrs.
11.4 yrs.
10.8 yrs.
11.3 yrs.
Understanding and treating
brain conditions
conditions
11.0 yrs.
Basic
research for new medical
Basic
research
technologies
for new medical
technologies
10.6 yrs.
Najpomembnejše tehnologije na področju Ved o življenju
: Študij možganov
“Top 10”
: Nove medicinske tehnologije in zdravila
: Regenerativna medicina
Topic
Area
Effective technology to prevent cancer metastasis.
Basic research for new
medical technologies
2020
/ 2030
Technology for immediate, complete control of allergies based on elucidation
of the immunoregulatory mechanisms and environmental factors that lead to
hay fever, atopic dermatitis, and other allergies.
Treatment for preventing the progression of Alzheimer's disease.
Basic research for new
medical technologies
2015
/ 2027
Understanding and
treating brain conditions
Understanding and
treating brain conditions
Technology for measuring
biological substances
Understanding and
treating brain conditions
2019
/ 2030
Basic research in drug
development
2015
/ 2026
Environmental and
ecological biology
Regenerative medical
science
Basic research for new
medical technologies
2014
/ 2024
Elucidation of the etiology of manic-dpressive psychosis at the molecular
level.
Technology to detect a cancerous tissue of the diameter smaller than 1 mm
presenting anywhere in the body.
Elucidation of the etiology of schizophrenia at the molecular level.
Technologies for drug development to predict bioactivities of proteins such as
interactions between protein and protein, between proteins and DNA or RNA,
and between proteins and synthetic compounds from their higher order
structure.
Mass production technology for fuels and bioplastics utilizing plants and
microorganisms.
Technology to manipulate stem cell differentiation and growth for induction of
functional cells to use for therapy.
Effective cancer prevention measures can be implemented by clarifying the
relationships among multiple environmental risk factors associated with
cancer.
Year
2020
/ 2014
/ 2023
2022
/ -
2016
/ 2029
2020
/ 2030
Tehnološka pot
Regenerativna medicina
2005 2010 2015 2020 2025 2030 2035
Long-term organ cultivation and preservation
technology for organ transplants.
Razvoj
osnivne
tehnologije
Izdelava
umetnih
organov
Reprograming technology to create stem
cells from differentiated somatic cells.
Technology to manipulate stem cell
differentiation and growth for induction of
functional cells to use for therapy.
Technology to utilize animals as a bioreactor
to produce organs and tissues to transplant
into humans.
Artificial retinas to give sight to the visually
impaired.
Artificial organs incorporating human cells
and tissue.
Synthetic technology for artificial cells with
functions such as cell membrane transport,
material transfer, and energy conversion.
Timescale for commercial opportunities
Therapeutics
Value
Research applications
Enabling technologies
Cell therapies
Growth factors
Manufacturing
Drug screening
Toxicity testing
Research tools
Clinical trials
Training
5
Cell banking
10
15
20
Time (years)
Translation of stem cell research into commercial
products
Stopnje:
Applied
Development
Basic Research
Clinical
Therapies
Manufacturing
Infrastruktura
:
Universities,
Research
Institutes
Biotech
SMEs
Pharma
Clinicians
Deležniki:
Government / regulatory agencies
Financiranje:
????
Commercial funding
VC, pharma
Research Councils
Charities
Funding Gap
Noben uspeh ni dokončen,
nobena napaka ni nepopravljiva:
šteje le pogum, da nadaljuješ.
Winston Churchill