112-lesson-3 - Macmillan Academy

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Transcript 112-lesson-3 - Macmillan Academy

Starter
• Explain why beetroot in a beaker of hot
water will change the colour of the
water whereas beetroot in a beaker of
cold water will not
• Explain the term “cell signalling” in no
more than 20 words
Learning objectives
• Recall examples of cell signalling
• Describe “cell signalling”
• Explain the role of membrane-bound
receptors as sites for hormone and
drug binding
Receptors for hormones
• Usually protein or glycoprotein
molecules
• E.g. insulin effects
• Increases the number of glucose
channels in the membrane increasing
uptake
• This increases the uptake of glucose
Receptors for drugs
•
•
1.
2.
3.
Page 28 information on aspirin
Separate the information into sections
Normal response to injury
Desired response to Aspirin
Undesired response to aspirin
Viruses
• How do they get into cells?
• What can we say about the shape of the
virus and the shape of the receptor?
• What does the virus do once it is in the
host cell?
Toxins
• How do you think they work?
Plenary
1. Suggest how flu viruses infect human cells
of the respiratory tract
2. Name two target tissues for insulin
3. Botulinum toxin binds to the ends of
nerves and stops them from releasing
chemicals that normally cause muscles to
contract. There are 8 different boltulinum
toxins, some stronger than others. Suggest
why some are more potent than others