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Cutaneous Leishmaniasis Leishmania tropica Oriental Sore Cutaneous Leishmaniasis • Found in arid regions (Mediterranean, Middle East). Cutaneous Leishmaniasis • Found in arid regions (Mediterranean, Middle East). • Vector is Phlebotomus sergenti. – Lives in more barren/sandy areas – Needs moisture during mating – Will hide in cracks Cutaneous Leishmaniasis • Incubation is a month or two. Cutaneous Leishmaniasis • Incubation is a month or two. • Then an open sore occurs Size of a quarter anywhere on the body. Cutaneous Leishmaniasis • Incubation is a month or two. • Then an open sore occurs Size of a quarter anywhere on the body. • Will heal up spontaneously within a year. Cutaneous Leishmaniasis • Can be transmitted by touch and flies to other open wounds etc. Cutaneous Leishmaniasis • Can be transmitted by touch and flies to other open wounds etc. • Penastan is drug of choice. Cutaneous Leishmaniasis • Can be transmitted by touch and flies to other open wounds etc. • Penastan is drug of choice. • Can get vaccinated for in the Middle East! Chiclero Ulcer Leishmania mexicana and Leishmania tropica Yucatan Peninsula and Central America. Sand flies in the genus Lutzomyia serve as vectors. Mucocutaneous Forms 1) Espundia. Espundia Leishmania braziliensis Most common in Brazil Sand flies in the genus Lutzomyia serve as vectors. Espundia Leishmania braziliensis • Die because of difficulty of breathing, eating and bacterial infections. Espundia Leishmania braziliensis • Die because of difficulty of breathing, eating and bacterial infections. • Can also localize in larynx loss of voice. Espundia Leishmania braziliensis • Die because of difficulty of breathing, eating and bacterial infections. • Can also localize in larynx loss of voice. • Pentastam drug of choice, however most people are not treated. Espundia Leishmania braziliensis • Die because of difficulty of breathing, eating and bacterial infections. • Can also localize in larynx loss of voice. • Pentastam drug of choice, however most people are not treated. • Reconstructive surgery.