Transcript Procurement of ACT`s

Procurement of ACT's
Informal Workshop on Prequalification of Antimalarial
Drug Products
Geneva, 5th May 2004
WHO/UNICEF JOINT
REQUEST FOR PROPOSALS
The interim solution
Françoise Mas,
Contracting and Procurement Services
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Procurement of ACT's
WHO/UNICEF Interim solution
MARCH 2003
•No ACT prequalified, nor likely
to be in the short term
•Two countries have adopted
Artesunate + Amodiaquine first
line treatment
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Procurement of ACT's
WHO/UNICEF Interim solution
In April 2003, tripartite meeting to
discuss possible solutions and actions
until a sufficient number of products
are pre-qualified
WHO/UNICEF cooperation on selection
and procurement.
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WHO/UNICEF joint tender 2003
Evaluation based on the UNICEF product quality
questionnaire (similar to WHO's)
Criteria included GMP certification, registration
information (countries), API, stability reports, she
life and storage conditions
Quality assurance based on a review of the
documentation submitted jointly by UNICEF
Pharmaceutical Team and WHO (EDM and
Procurement with assistance from QSM when
necessary)
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UNICEF/WHO joint tender 2003
No co-packaged product could be selected after
evaluation, mainly due to lack of stability data.
By June, only two products (in separate blisters)
satisfy the evaluation and allow to place the first
orders, but at a high cost ($ 2.60 per adult
treatment).
By December we had a choice of three Artesunate
50mg and two for Amodiaquine 150mg base,
lowering the price of adult treatment to $1.68.
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WHO/UNICEF joint tender 2004
By end of January 2004, still no change in the
prequalification status for ACTs.
WHO and UNICEF decide to repeat the joint
tender exercise, this time including all the
current WHO recommended ACTs, as well as
separate blisters and the range of invitees is
also expanded.
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WHO/UNICEF joint tender 2004
Offers received from nine companies on
tender opening (23 February 2004)
Joint evaluation begun on 9 March in
Copenhagen with WHO staff (EDM and PRS)
should be concluded in June.
We aim to have at least two suppliers for
ACTs.
Once the products are selected, WHO can
sign letters of agreement with suppliers in
order to to include products in the WHO eprocurement catalogue.
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WHO/UNICEF joint tender 2004
Artesunate + Amodiaquine
Artesunate + Mefloquine
Artesunate + SP
SP + Amodiaquine
5
1
1
1
offers
offer
offer
offer
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Other on Malaria Treatments
WHO/Novartis agreement for supply of
Coartem to UN, NGOs and Governments
Teamwork between Procurement, Roll
Back Malaria and the EDM Quality
Assurance Unit for new products
through the Pilot Pre-qualification
Project.
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