Transcript Method of Administering Drugs

Method of Administering
Medication
Kevin Murphy
Administration Methods
• One way to administer a drug is to taking it orally either by
pills, capsules, or by drinking a liquid.
• Intravenous (IV) which administers the medication directly
into the blood.
• Intramuscular injection which is directly into a muscle.
• Intratumoral injection which is directly into a tumor
• You can use a cream that you rub onto your skin.
History of Administering Drugs
• Orally taking medication has been around since ancient Egypt.
• In 1853 a surgeon invented a small syringe.
• In 1935 the slow drip was first used which is a continuous
method of transfusion.
• In 1953 first mass-produced disposable syringe and needle was
developed for the mass administration of one million
American children with the new polio vaccine.
• From 1970 to 1980 numerous controlled drug delivery
capsules where invented.
• By 2010 there were numerous long relief medications that can
last up to 24 hours.
Current Day Delivery Systems
• At the present time, there are a huge number of drug delivery
technologies.
• Today, drug delivery companies are engaged in the
development of multiple platform technologies for; controlled
release, delivery of large molecules, liposome's, taste-masking,
oral fast dispersing dosage capsules or gels, and technology for
insoluble drugs.
• Another delivery technologies are artificial DNA
nanostructures, biodegradable particles.
Future Direction
• In the next 10 to 20 years, protein and peptide based drugs will
constitute more than half of the new drugs going onto the
market.
• Gene therapy is also expected to emerge as one of the major
ways of treating diseases. Doctors will replace a mutated gene
with a therapeutic gene.
• Biodegradable polymeric delivery technologies will be longer
lasting.
• Scientists are also trying to make medicated inhalants that you
can breathe in by using an inhaler.
Limitations
• Often large molecules degrade rapidly in the blood
stream and they have a limited ability to cross cell
membranes and generally cannot be delivered orally.
• Liposomes tend to have stability issues and are hard
to create in large scales.
• Sterilization limitations when using nano particles.
• Diminished potency due to drug metabolism in the
body
Bibliography
• http://www.lymphomation.org/drug_admin.htm
• http://www.lls.org/diseaseinformation/managingyourcancer/tre
atmentnextsteps/typesoftreatment/chemotherapyotherdrugthera
pies/typesofdrugs/methodstoadminister/
• http://www.touregypt.net/historicalessays/medication.htm
• http://www.pharmanet.com.br/pdf/drugdelivery.pdf
• http://en.wikipedia.org/wiki/Targeted_drug_delivery
• http://www.youtube.com/watch?v=yNX0FuXEFWw&feature=
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