Transcript features - Technology Transfer Group

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Probiotics and Nutraceuticals
Microbial genetics
Antimicrobial chemotherapy
Molecular virology, Recombinant DNA technology
Structural Biology and Protein Chemistry
DNA-interacting Molecules
Enzyme Inhibitors
Structure Function of Proteins
Nucleosides as Antivirals
Biomimetic Chemistry of Metals
Computer Simulations of Biomolecules
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Bio Hydrogen Lab
Bio Process Lab
Biochemical & DSP Lab
Cell & Molecular Biology Lab
Micro & Immunotech Lab
Plant Biotech Lab
Computation Lab
Medical Biotechnology Lab
Fermentation Technology Lab
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Air-lift bioreactor
Atomic absorption
spectrophotometer
Centrifugal evaporator
Darkroom/Cold room /
Radio-isotope facilities
DNA finger printing
ELISA reader
Fermentation Technology
Gas Chromatograph
High speed refrigerated
cooling centrifuge
Liquid nitrogen storage
facility
Milli-Q water purifier
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Netzs Thermal Analyzer
(DSC, TGA, DTA)
Perkin Elmer FT IR
Spectrometers
Perkin Elmer CHN Analyzer
Digital Polarimeter (JASCO)
Fluorimeter
CH Electrochemical
Analyzer
Thermal Analyser
UV & Visible
Spectrophotometer
Bruker AC 200 MHz NMR
Spectrometer
Cyclic Voltammeter Model
P9001
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Magnetic Nano-Particle for Cancer Diagnostics
Extraction of Chemical from Marine Bacteria for
Chemotherapy
Anti-Diabetic Drug from a Probiotic Bacterium
Bench-Scale Technology for Manufacture of ProBiotics
Non Invasive Sterile Drug and Device
Manufacturing System
Extraction of Polyphenols from Green Tea Leaves
Smart-Reversible Inhibition of Sperm Under
Guidance
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Technology development & transfer for selected medicinal
plants: approach through R&D and ex-situ cultivation
Biosynthetic silk hydrogel extracellular matrix analogues for
mammalian cell support and drug delivery
Studies on the immunomodulatory properties of Aloe vera
gel and its products
Exploring the immunomodulatory potential of mushroom
glucan/proteoglucan as Biological response modifier in
cancer therapy
Enantiomeric separation of chiral drugs by micellar
electrokinetic capillary chromatography
A rational approach towards anticancer drugs and
chemosensors
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Herbal/ bioproduct development
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Water pipe fermented tobacco products
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Biocatalyst based continuous production of
biodiesel
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The UC Berkeley – IIT Kharagpur collaboration
focused on biofuels (energy), and biotech
(healthcare)
Indo-Norwegian- Institute collaboration on
Characterization of two histidine kinases and
their cognate response regulator
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Research Hub
Strong intellectual capital
Produces unparalleled technically competent
students
Healthy balance of core and non core engineering
courses
Emphasis on hands on, learn as you do approach
Numerous successfully completed projects
FEATURES
•Magnetic nano-particle coated with folic acid
•After injection to patient the particle is absorbed selectively by cancer cell
and the lesion is easily identified by Magnetic Resonance Imaging
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Low cost
high efficiency for detection
better than the conventional X-ray
technique
Perfectly harmless to the body
FEATURES
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Biosurfactants isolated from a marine bacterium are found to have
significant antimicrobial activity and can be used in chemotherapy.
USP
•Non-hemolytic in nature
•Does not harm normal cell lines due
to low concentration
•Shows properties such as metal
binding, emulsification
FEATURES
•An exo- polysaccharide with potential anti-diabetic activity
•Produced by simple fermentation and purification process
•Characterized in terms of sugar monomers and its ability to reduce blood
glucose levels in an animal model.
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First anti-hyperglycemic exopolysaccharide molecule from
a pro-biotic
GRAS(Generally Regarded As
Safe) by US FDA
Potential drug candidate for
both type 1 and type 2
diabetes.
far better results in
comparison with standard
drugs for type 2 diabetes
Biodegradable, non- toxic and
has no side effects
FEATURES
•Manufacturing endospores of a pro-biotic bacterium at a lab scale
•Can lead to development of some neutrateuticals
•Maximum of 6 x 1012 spores/gm have been obtained
•The process is optimized and stabilized in a 10 l reactor
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Confirms to all the
characteristics of a GRAS
organism (US FDA)
Produced endospores can be
stored under nonrefrigirative condition
Very high potency and L(+)
Lactic acid levels
Proven to produce
bacteriocin like antimicrobial
substances, antioxidant
exopolysaccharides
FEATURES
•Sterile drug or a device manufacturing system with controlled and enclosed microenvironment
•All manipulations are performed by magnetic coupling across the enclosure and
mini-robots placed within, controlled by electromagnetic coupling
•No invasion of operating personnel; gloves; control cords into the manufacturing
space
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Cost effective (70% less than
conventional clean room
facility)
Minimal manufacturing zone is
maintained at the best ‘Clean’
conditions
No requirement of electricity or
human operator
Less particle contamination and
transparency maintained by
glass or polymeric sheet
FEATURES
•Centrifugation of tea juice, followed by special membrane
based filtration process and drying of concentrated liquor to
produce 60-70% pure polyphenol powder
•Based on water extraction - without addition of any
chemicals
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“Green Process“absolutely safe for
human consumption
FEATURES
•Non-hormonal male injectable contraceptive in the form of a clear gel
•Within an hour after injecting into the vas deferens, produces an electrical
charge to nullify electrical charge of spermatozoa
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Composition is made to be
effective for more than 10 years
(long lasting)
Safe with almost no side effects
Antimicrobial
Non-surgical
Cost effective