Comorbidity, Prevalance and Trends General Definition of Comorbidity
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Transcript Comorbidity, Prevalance and Trends General Definition of Comorbidity
Comorbidity,
Prevalance and
Trends
General Definition of
Comorbidity
Historical Origins (Feinstein, 1970)
General Definition: Two or more physical
illnesses, psychological conditions or a
mix of the two
Rule rather than the exception
Distinguish:
Covariation
Co-occurrence
Overview of the NCS,
NCS-R
http://www.hcp.med.harvard.edu/ncs
National Comorbidity Survey (1990-1992), First
nationally representative survey of mental
disorders using research diagnostic interviews
using DSM-III-R criteria
National Comorbidity Survey-Replication
(2001-2003), N = 10,000, used DSM-IV criteria
Follow up on disorders from the first NCS and
to explore particular questions in further depth
Rates of Comorbidity
Nearly half of all people with a mental disorder
have two or more disorders
More than half of people with a substance use
disorder and more than 75% of those within
treatment for substance abuse or dependence
als meet criteria for a mental disorder
Individuals frequently meet criteria for three or
more disorders
Disorders may have indirect or direct causes—
more on this later
Categorical Versus
Dimensional
What do you gain with a categorical
system?
What do you lose with a categorical
system?
Are categories extreme ends of
continuua or do they represent
something qualitatively different?
Medical model versus operationalism
Examples of Taxa
Meehl http://www.tc.umn.edu/~pemeehl/
asserts that the following disorders may
be true taxons
Schizophrenia
Bipolar depression
Unipolar major depression
Antisocial personality
Modeling Comorbidity
Bivariate Comorbidity
Multiformity Models
Causation Models
Independence Models
Spurious Associations
Hypothetical Multivariate Model
Dual Diagnosis: An
application of Comorbidity
Berken’s Fallacy: Individuals with
multiple disorders are more likely to seek
treatment so that estimates of the
prevalence of comorbid disorders will be
higher in clinical samples
Inpatient vs Outpatient status
Chronicity of Illness
Severity of Illness
Methodological issues
contd
Definitional issues vary from problem use
of a substance to abuse or dependence
Which substances are included in the
definition makes a difference
Disconnected areas of study
Effect of Comorbidity
Comorbidity affects a disorder’s course
probnosis, assessment, treatment and
outcome
Dual diagnosis: When a person meets criteria
for one or more Axis I or Axis II mental
disorders and meet criteria for one or more
substance use disorders
Individuals with a lifetime history of a mental
illness are 2.3 times more likely to have lifetime
alcohol use disorder and 4.5 times more likely
to have a substance use disorder
Disorders with Highest
Comorbidities
ASP (84%)
Bipolar Disorder (61%)
Schizophrenia (47%)
Panic (36%)
OCD (33%)
MDD 927.2%)
Men and women with PTSD were 5 and 1.4 times more
likely to have a drug use disorder than those without
Overall mental disorders yield at least double the risk
of a lifetime alcohol or drug use disorder
Overall Rates of
Multimorbidity
It is not uncommon for patients to have 3
or more disorders: 14% of the NCS
sample had 3 or more diagnoses and
these respondents accounted for almost
90% of the severe 12 month disorders
and well over half of the lifetime and 12
month diagnoses in the sample.
Impact of Dual Diagnosis
How are patients affected?
Assessment issues
Underlying theories
Common Factors
Secondary Substance Abuse
Secondary Psychiatric Disorder
Bidirectional Models
Prevalence and Treatment
of Disorders 1990-2003
No notable change in the prevalence or
severity of mental disorder in the United States
between 1990-1992 or between 2001-2003
Most treatment for disorders falls below the
minimal standards of quality
Treatment typically brief (affects duration of
particular disorder more than prevalence of
mental disorder
Most treatment delivered in the medical sector
for disorders below clinical threshold.