Transcript Slide 1

What our Brains Remember as
our Bodies Age
Dawne Clark, PhD
Centre for Child Well-Being
Mount Royal University
May 15, 2010
What does our brain do for us?
Human beings, as a species, have three primary
functions: to survive,
to procreate,
and to raise our young
Our brain is the organ of the body which allows us
to organize and fulfill our three primary functions
(Perry, 2004)
Some Amazing Brain Facts!
• Our brains begin to develop only 3 weeks after
conception!
• The brain is about 75% water and weighs
about 3 pounds.
Your skin weighs about twice
as much as your brain!
More Facts!
• There are 15 times more brain cells in your head
than there are people on the planet!
• The number of possible
interconnections amongst
the neurons in one brain
exceeds the estimated
number of atoms in the
entire universe!
Our brain is an experiential organ
What happens when the brain has
negative experiences?
An Analogy
75%
25%
Negative experiences before birth
• Prenatal
– Genetic challenges, chromosomal damage
• i.e. Autism Spectrum Disorders, Schizophrenia
– Teratogens
• i.e. nicotine, alcohol, drugs
We all experience stress –
even children
Stress
Dr. Sonia Lupien describes the
components of severe stress:
• N – Novelty
• U – Unpredictability
• T – Threat to the ego
• S – Sense of loss of control
Some stress is okay or even good –
but don’t go NUTS!
Chronic Anxiety and
Persistent Fear
• Abuse, neglect, ongoing domestic violence
• May experience lifelong consequences as a
result of disruptions to the developing
structure of the brain
• These states trigger extreme, prolonged
activation of the child’s stress response
system
(National Scientific Council on the Developing Child, 2010)
How fear and anxiety affect the
developing brain
What this damage may look like
• Distorted perception and response to
threat
–
–
–
–
serious anxiety disorders
problems with social interactions
greater vulnerability to stress
greater likelihood of responding
aggressively
• A child’s ability to learn
– Memory
– Problem-solving abilities
Adverse Childhood Experiences
(ACE) Study
Largest population health study (over 17,000)
relating early childhood experiences to adult
health issues
• Obesity clinic
– Inability or unwillingness to lose weight
– Memories of adverse experiences before
age 18
Nine most common
adverse experiences
1 Recurrent physical
abuse
2 Recurrent emotional
abuse
3 Emotional or physical
neglect
4 Contact sexual abuse
5 Domestic violence
6 Alcohol and/or drug
abuse in the home
7 Family member who is
chronically depressed,
mentally ill, suicidal or
institutionalized
8 One or no parents
9 An incarcerated
household member
Main Findings of ACE Study
ACE Score
0
1
2
3
4 or more
Women
34.5
24.5
15.5
10.3
15.2
Men
38.0
27.9
16.4
8.6
9.2
Average
36.1
26.0
15.9
9.5
12.5
ACEs are surprisingly common among
middle class Americans
ACEs have an impact
even up to fifty years later
• alcoholism and alcohol
abuse
• chronic obstructive
pulmonary disease (COPD)
• depression
• fetal death
• health-related quality of life
• illicit drug use
• ischemic heart disease (IHD)
• liver disease
• risk for intimate partner
violence
• multiple sexual partners
• sexually transmitted
diseases (STDs)
• smoking
• suicide attempts
ACE score and smoking
ACE score and illicit drug use
Impact of ACEs over the lifespan
Why is it important to know about the
Adverse Childhood Experiences Study?
• The ACE study provides
compelling evidence
that:
– ACEs are surprisingly
common
– They happen even in
“the best of families”
– They have long-term,
damaging consequences
Conclusion
We now know that:
• Early experiences impact the
developing brain
• The brain doesn’t forget
• The trajectory of development
over the lifespan is affected
– Learning and abilities
– Health
– Relationships
What can we do
to change the trajectory?
Dawne Clark, PhD
Centre for Child Well-Being
Mount Royal University
www.mtroyal.ca/wellbeing