Transcript Stop Smoking With Hypnotherapy Study

Stop Smoking With Hypnotherapy
Study
A Proposal
Bupropion studies
• 615 smokers – randomised to drug 100mg,
150mg, 300mg or placebo for 7 weeks
• Try to stop at 1 week
• For 300 mg - at 7 weeks[course end]
– 10.5% stop with placebo
– 24.4% stop with drug
• At one year point prevalence [ no smoking for last
week]
– 12.4% placebo
– 23.1% drug
Bupropion studies
• 893 smokers one of 4 treatments for 9
weeks – 12 month point prevalence
– Placebo oral + placebo patch  15.6%
– Bupropion 300mg + placebo patch 30.3%
– Nicotine patch + oral placebo  16.4%
– Bupropion 300mg + nicotine patch 35.5%
Bupropion studies
• Continuous absence rates =
– Bupropion alone 18.4%
– Bupropion +patch 22.5%
• Cost
– £86 + counselling – 5 sessions
Bupropion studies
• Problems with Bupropion
– 11% dry mouth
– 42% insomnia
– 6% hypertension { if given with patch}
– 1:1000 - fitting
Bupropion studies
• Contraindications
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Epilepsy
Pregnancy
History of fits
History of head injury
Diabetes on drugs or insulin
Patients on
• Theophylline Systemic steroids
• Antipsychotics
• Antidepressants
Hypnotherapy Studies
• Hypnotherapy
– Safe
– Specific
• Difficult to generalise
• Few published single session studies
Hypnotherapy Studies
• 226 Smokers [ Spiegel Frishholz Spiegel]
– Single session treatment
– 2 year follow up
• 53% stop at one week
• 23% stop at two years
Hypnotherapy Studies
• 40 patients [Berkowitz Townsend
Kohberger]
– Single session
• 25% stop at 6/12
Hypnotherapy Studies
• LCCH method
• Single sessions
• Cost £ 150 approx
• Easily learned
• No side effects
• Does it work ??
Hypnotherapy Studies
• LCCH study
– Single hypnotherapist
– LCCH method
• One hour session only
– Follow up one month to one year
– Postal Questionnaire
Stop Smoking With Hypnosis Study
Dear Sir or Madam:
You recently had hypnotherapy to help stop you smoking. We are conducting a
study to assess the effectiveness of this treatment. We would be very grateful if you
would be willing to spend a few minutes to complete this questionnaire and return it
in the stamped addressed envelope enclosed.
Date of Hypnotherapy
Name of Hypnotherapist
Before Hypnotherapy
How long had you been smoking ?
Years
How many did you smoke a day?
After Hypnotherapy
Did you Stop smoking
completely ,cut down or
continue smoking the same
number [ tick one only ]
Stopped
If You
stopped
completely
please indicate
how long you
stopped for by
ticking the
relevant box
1-3
months
Less than 1
month
Cut
down
Continued unchanged
4-6 months
1 year
So far I
have
stopped for
months
If you cut
down please
write the
number of
cigarettes you
have been
smoking in
each of the
periods after
hypnotherapy
I have not
restarted
Number
Smoked per
day Less than 1
month after
treatment
1-3
4-6 months
months
Did you use any additional treatment such
as nicotine patches, or chewing gum at the
time of hypnotherapy
If yes please describe
Yes
1 year
No
LCCH Study Results
• 59 questionnaires sent { follow up 1/12 to 1 yr }
– 35 Returned 59.3%
• Of those returned
– 30 stopped 85%
– 1 cut down 2.8%
– 4 continued unchanged 11..4%
• At one month
– 23 stay stopped 65.7%
LCCH Study Results
• Results beyond this unsatisfactory due to lack of
follow up
• BUT no known restarters after 6 months
– Restarters
• 3 at less than one month
• 4 at 1-3/12
• 2 at 4-6/12
– We have a definite 12 stopped at one year { 34% } but
as data is incomplete
• Could presume 21 stopped at one year which would be 60%
stop at one year
LCCH Study Results
Hypnosis Retrosepective Study Resutls
S=Stop C=cut down R=restarted I= incomplete data U = Unchanged NRT=Nicotine Replacement Therapy
Numbers Sent
Number
=
Returned Study Number Sex
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
41
44
27
31
30
17
2
49
32
42
16
11
34
33
3
28
52
14
40
50
6
13
5
57
58
19
35
46
55
10
24
53
45
29
Yrs smoked Cigs/day
F
M
F
F
F
F
F
F
F
F
M
F
F
M
F
F
F
F
F
F
F
M
F
M
M
F
F
M
F
F
M
F
F
M
F
16
23
20
7
11
5
30
13
10
20
31
20
30
10
7
15
12
40
1
30
33
13
14
20
20
15
16
16
20
24
26
30
16
27
38
20
45
20
20
20
15
35
30
30
25
40
30
10
12
15
25
20
45
7
25
30
20
22
20
20
20
10
15
12
15
30
20
20
7
20
59
Initial Result
<1/12
1-3/12
4-6/12
1 yr
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
C
U
U
U
S
U
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
RC
RC
C
U
U
U
RC
U
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
R
R
R
R
S
S
RC
RC
U
U
U
U
R
U
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
I
I
I
I
I
R
R
R
R
R
R
I
I
I
U
U
I
I
I
S
S
S
S
S
S
S
S
S
S
S
S
I
I
I
I
I
I
I
I
I
R
R
R
R
S
R
I
I
I
U
I
I
I
I
Summary of results
59 sent
35 back
=
59.32 percent
29 stop
=
82.86 percent
data in months Additional aidsNotes
20
18
15
16
14
14
17
20
21
20
14
15
9
8
7
7
7
4
3
3
2
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
NRT
NRT
3N
7N
NRT
6N
6N
2N
N
6N
3I
4N
4
Restarted at 20 months
Restarted at 15 months after drinking with smoking friend. Had furthur hypnotherapy - unsuccessful
gum, Restarted at < 1/12
gum, Restarted at < 1/12
Now stopped with zyban
Restarted at 4-6/12 then had furthur session and is now stopped
gum, Restarted at < 1-3/12
Stopped for one month then restarted at lower rate of 5 per day
Stopped for one month then restarted at lower rate o f4per day
Cut down for < 1/12 then back to normal amount
3 sessions
Stopped for 2 days
Hypnotherapy Proposal
• Randomised study - Possible Studies
• In conjunction with Community Stop Smoking
Clinics
• Single session LCCH method hypnotherapy Vs Bupropion +
counselling
• Possible arms
– Single session hypnotherapy
– Single session hypnotherapy + NRT
– Single session hypnotherapy + Bupropion
– Bupropion + counselling