Transcript Body’s Response to Long

THE BODY’S RESPONSE TO
LONG-TERM STRESS
The Effects of Cortisol
MELISA & SZERENA
WHAT IS CORTISOL?
• A regulatory hormone which is the body’s natural
response to high stress levels.
• Produced in the adrenal gland.
CORTISOL
PRODUCED BY THE ADRENAL GLAND
• Stress affects the body
• Receptor detects the stress
• Control center (CNS)
• Cortisol is sent to affected area
• Stress level decreases
ADRENALINE
• What does adrenaline affect in the body?
CORTISOL
• What stimulates cortisol release?
• What is the purpose of cortisol release?
• What causes abnormalities of cortisol release?
NEGATIVE FEEDBACK CYCLE
NEGATIVE FEEDBACK CYCLE
Control Center:
Pituitary Gland
Adrenocorticotropic
Hormone (ACTH)
Effector: Adrenal Gland
releases Cortisol
Corticotrophin Releasing
Hormone (CRH)
Cortisol release
Receptor: Hypothalamus
Homeostasis
POSITIVE EFFECTS OF CORTISOL
A SMALL AMOUNT OF CORTISOL
• Cortisol triggers the body to adapt to “fight or flight”
situations
• Temporary Enhanced physical ability
• Inhibits the inflammatory response
• Regulation of Insulin levels
• Proper glucose metabolism
• Regulation of blood pressure
• Heightened memory functions
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http://www.sebastianfitnesssolutions.com/blog/the-positive-effects-of-cortisol/
NEGATIVE EFFECTS OF CORTISOL
A LARGE AMOUNT OF CORTISOL
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Anxiety
Depression
Digestive problems
Heart disease
Sleep problems
Weight gain
Memory and concentration impairment
Decreases the function of immune system
Shorter life expectancy
Decreases bone density
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http://www.mayoclinic.com/health/stress/SR00001
DRUGS CONTAINING CORTISOL
• DRUG CLASS: Glucocorticoids
What are they essential for?
Examples: Decadron
Acthar
Hydrocortisone
DRUGS CONTAINING CORTISOL
• Decadron (dexamethasone)
What conditions does Decadron treat?
What are the effects of Decadron use?
DRUGS CONTAINING CORTISOL
• Acthar
What conditions does Acthar treat?
What are the effects of Acthar use?
DRUGS CONTAINING CORTISOL
Hydrocortisone
What conditions does Hydrocortisone treat?
What are the effects of Hydrocortisone use?
CONCLUSION
Don’t stress out.
Eat chocolate, not laptops.
According to research published in 2009 in the
journal "Proteome Research" and reported by
"The Huffington Post", eating 1.4 ounces of dark
chocolate daily for two weeks is associated
with lower levels of the stress hormone cortisol.
SOME VERY RELAXED ANIMALS