Transcript Slide 1
PERSONALIZED MEDICINE What is Personalized Medicine? • Information-based healthcare – Person-by-person: high content, resolution & fidelity – Ushered in by the sequencing of human genomes – Enhanced by new biological knowledge – “Right drug, right patient, right dose, right time” – But NOT limited to management of therapy Overall Goals • Improve outcomes – Disease care – Health care • Reduce costs How? • Disease care – Target medicines precisely (“pharmacogenomics”) – Administer medicines safely (“toxicogenomics”) • Health care – Predict disease susceptibility • Prevent disease – Detect early onset of disease • Preempt disease progression How? • Because Health-care trumps Disease-care – Create a healthier population – Shift more responsibility for care to the individual – Reduce overall “healthcare” costs? HEALTH personalized MEDICINE “pH” What are potential disadvantages? • • • • • • • Greater costs of diagnostics/biomarkers Smaller patient markets for therapeutics Need to track individual health information Necessity for accelerated HIT Diagnoses without treatments Re-education of healthcare professionals Distraction from other $ saving opportunities As the train is leaving the station… Does California Government have a role In the ”Personalized Health Rush”? If so, what? What priorities? How to create a recommended plan? What priorities? • Economics & reimbursement – Short-term vs. long-term perspective – Micro-economics vs. macro-economics • Regulation & Policy development – Privacy & Non-discrimination – Redundancies & confusions – Unintended consequences • Health Information Technology – Encouraging innovation – Educating & training – Integration and implementation Task Force Leaders • • Macroeconomics: Richard Levy Regulation: William D. Young – Kathy Hibbs • HIT: Ramesh Rao Next Step? • Complete the Funding -Steven E. Brenner