Transcript A copy of Dr. Freedman`s presentation slides can be

Career Opportunities in Biotechnology
and Drug Development
Career Opportunities in the Life
Sciences
Toby Beth Freedman, Ph.D.
SEBA, October 12th, 2012
10-11 am
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
1
Today’s Talk
•
•
•
•
Career overview
Transitioning from Academia to Industry
Job search strategies
If there is time, current economy
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
2
Definitions
“Pharmaceuticals”
• Chemical synthesis
• “Small molecule drugs”
• Pfizer, BMS, Merck
• Aspirin, statins, Viagra, antibiotics, taxol,
Prozac, antihistamines, anti-inflammatories
Definitions
“Biotechnology”
• Biologics: DNA, RNA, protein,
viruses, antibodies, hormones
• “Large molecule drugs”
• Genentech, Amgen, Genzyme,
Gilead, Biogen
• Rituxan, EPO, Enbrel, Gleevec,
Herceptin, insulin, HGF
Definitions: Biotechnology Also
Biotools, Reagents & Services
• Instruments and tools,
enabling technology, services
• Microscopes, reagents,
software, services
• Affymetrix, Zeiss, Promega,
Covance, BCG
Definitions
“Medical Devices”
• Instrument or software
for diagnosis or
therapeutic purposes
• J&J, GE, Medtronic, Tyco, Philips, Boston
Scientific, Abbott
• Stents, MRI, surgical equipment,
defibrillators, wheelchairs
Biofuels
Definitions
“Healthcare”
• Hospitals/HMOs,
Insurance companies
• Kaiser, Sutter Health
Three Main Career Paths for Students
Academia
Tenured
Professor
Government,
Research
Institutes, NonProfits
Dean
Director or
Other
Industry
CEO
VP
Director
Tenure track
Educator
Scientist or
Other
Manager
Fellow or
Principal
Scientist
Track
Science and
Business
Student
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
9
My Experiment
• A comprehensive, systematic assessment
of careers for life science professionals
• Not hypothesis driven
• Career choices for science and medical
backgrounds
• Resource guide for career planning—so
much information that readers identify a
career that suits their skills, interests,
goals and personality attributes
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
10
Goals: Be Sure To Enjoy a Job
“If you are doing what you love, then it’s not
really ‘work’”
Peter David
Goals: Get on the Right Track
Methods
•
•
•
•
•
•
•
200+ interviews
1 hour telephone informational interviews
Mostly VPs, Ph.D.s or MDs
10 interviews per chapter
Compiled, analyzed and summarized
Took three years
Published by Cold Spring Harbor
Laboratory Press and is on Amazon
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
13
Results: So Many Careers To Choose!
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
14
Product Development Overview
Preclinical Studies
Discovery
Research
Lead
Optimization
of Drug
Candidates
Discovery Research
Preclinical
Studies
Bio/Chemical
Process
Development
IND
filing
Clinical Trials
Scale-Up /
Manufacturing
NDA
or
BLA
filing
FDA
review
Product
Launch!
Commercial
Operations
and Sales
Phase
IIIB/IV Trials
Medical Affairs
Clinical Development and
Regulatory Affairs
Commercial Operations: Marketing,
Sales, and Technical Support
Chemical and Biological Development, Operations and Manufacturing, Quality
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
15
Careers for Engineers: Medical Device
and Biotech Tools Companies
Discovery
Preclinical
Recruiting Research
Research
Venture
Capital &
Banking
Law
Product
Development
Management
Consulting
Project
Management
Bio IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Business
Development
Medical
Affairs
Marketing
Corporate
Communications
Product
Support
Sales
Careers in Research
Venture
Capital &
Banking
Law
Discovery
Preclinical
Recruiting Research
Research
Bio/Pharmaceutical
Product
Development
Management
Consulting
Project
Management
Bio IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Business
Development
Medical
Affairs
Marketing
Corporate
Communications
Product
Support
Sales
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
17
Having a business background is an
advantage
Discovery
Preclinical
Recruiting Research
Research
Venture
Capital &
Banking
Law
Bio/Pharmaceutical
Product
Development
Management
Consulting
Project
Management
Bio IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Business
Development
Medical
Affairs
Marketing
Corporate
Communications
Product
Support
Sales
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
18
Do you want to be a CEO one day?
Venture
Capital &
Banking
Law
Discovery
Preclinical
Recruiting Research
Research
Bio/Pharmaceutical
Product
Development
Management
Consulting
Project
Management
Bio IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Business
Development
Medical
Affairs
Marketing
Corporate
Communications
Product
Support
Sales
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
19
Careers where you can earn the most
money
Venture
Capital &
Banking
Law
Discovery
Preclinical
Recruiting Research
Research
Bio/Pharmaceutical
Product
Development
Management
Consulting
Project
Management
Bio IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Business
Development
Medical
Affairs
Marketing
Corporate
Communications
Product
Support
Sales
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
20
Hot Jobs
Venture
Capital &
Banking
Law
Discovery
Preclinical
Recruiting Research
Research
Bio/Pharmaceutical
Product
Development
Management
Consulting
Project
Management
Bio-IT
Services
Quality
R&D
Clinical
Development
Operations
Commercial
Operations
Operations &
Manufacturing
Regulatory
Affairs
Medical
Affairs
Business
Development
Marketing
Corporate
Communications
Sales
Product
Support
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
21
Positions for students
Analysts/Assoc
Kauffman Fellow
Portfolio, SRA
Consultant
Project coordinator
Analyst
Budget, strategy
Quality systems
Many
Liaison
Analyst
Marketing
Marcom, AAAS Fellow
Marketing, MR
Tech Support, FAS
Sales reps, trainers, managers
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
22
Positions for PhDs/Postdocs
Patent agent, advisor, USPTO
Research Analysts/Assoc
Kauffman Fellow
Consultant
Scientist I
Project coordinator
Bioinformatics
Medical writer, IT
QC chemist
Startups
FDA, Liaison
OTT, Portfolio
MSL, Scientific affairs
Marcom, AAAS Fellow
Market research
Tech Support, FAS, Trainer
Technical sales rep, FAS
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
23
So Many Careers To Choose!
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
24
Many areas to consider
Table 6-1: Biotechnology and Drug Development Overview... Where the Jobs Are
Drug Discovery
& Development
Biotechnology
“Tools”
Biotechnology
Services
Other Pharma/
Biotech Areas
Government
Institutions
Medical
Devices
Academia
Pharmaceutical
companies
Reagents and
Chemical suppliers
Management consulting
and accounting firms
Agricultural
Medical devices
Tech transfer
Biotechnology
therapeutic
companies
Instruments (e.g.,
microscopes)
Law firms
Industrial
biotechnology
Food and Drug
Administration
(FDA) and CBER
Diagnostic
companies
Venture capital and
investment banking
Molecular
diagnostics
Industrysupported labs
and institutes
Vaccines
Drug delivery
Molecular
Diagnostics
Platform companies
(e.g., genomics,
proteomics,
nanotechnology)
Bio-IT
Software and
hardware
Molecular
diagnostics
Recruiting firms
Contract research
organizations (CROs)
Contract manufacturers
(CMOs)
Research and clinical
testing: clinical labs,
customized antibodies
Bio-IT
Veterinary
companies
Foundations, nonprofits, social
philanthropy
Clean tech/energy
Nanotech
Journalism
Other agencies and niche
providers: PR, advertising, Viticulture
market research, medical
communications
Consultants
Centers for
Disease Control
(CDC)
National Institutes
of Health (NIH)
eHealth
Education
HC Informatics
Telemedicine
US Patent and
Trademark Office
(USPTO)
Program
management
Incubators
Research institutes
and government
labs
Homeland security
& defense
CIA, FBI, and
NASA
Trade
commissions
Crime labs
forensics
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
25
Careers in Healthcare
Healthcare
Practitioners Nursing
Associated Careers
and Therapists
Technologists and
Technicians
Rehab
Therapists
Healthcare
Administration
Insurance
Industry
Physicians
Licensed nurses
Acupuncturists
Audiologists
Dentists
Nurse anesthetists
Dental hygienists
Optometrists
Nurse midwives
Dietitians and nutritionists
Podiatrists
Nurse practitioners
Genetic counselors
Veterinarians
Home health aides
Pharmacists
Admitting officers
Accounting and
finance
Coordinators of
health wellness
Environmental health
and safety
Food service
Health education
Health information
technologists
Human resources
Librarians
Public relations
Nursing home
directors
QA directors
Geriatric care
managers
Medical records
Medical billing,
claims, patient
accounting
Medical secretaries
Mental health
workers
Administration
Registered nurses
Anesthesiologists
Blood bank techs
Cardiovascular techs
Radiology techs
Clinical lab techs
Cytotechnologists
Cardiovascular
Nuclear medicine
Dental assistants
Dental lab techs
Diagnostic medical
sonographers
Diagnostic imaging
Dietetic techs
Electroencephalograph
Emergency techs
Paramedics
Food techs
Histology techs
Ophthalmic techs
Optometric techs
Perfusionists
Phlebotomists
Pulmonary techs
Radiation therapy techs
Surgical techs
Veterinary assistants
Art therapists
Chiropractors
Surgeon assistants
Psychologists
Nurse’s aides
Occupational therapists
Opticians
Orthotists and prosthetists
Physical therapists
Recreational therapists
Respiratory therapists
Pediatric occupational
therapists
Biomedical engineers
Biomedical equipment
techs
Biomedical photographers
Biomedical writers
Child life specialists
Dietary managers
Geriatric social workers
www.careersbiotech.com
Certified athletic
trainers
Dance movement
Home health aides
Music therapists
Occupational
therapists
Patient reps
Physical therapists
Psychiatric aides
Recreational
therapists
Rehab counselors
Respiratory
therapists
Social services
aides
Speech language
pathologists
Substance abuse
counselors
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
Actuaries
Agents and
brokers
Claims adjusters
Loss control
specialists
Medical
insurance billing
and coding reps
Medical claims
reviewers
Public relations
Service reps
Sales and
marketing
Underwriters
26
Ideal Job
Skills
Interests
Ideal
Job
Values/Goals
$$$/Market
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
27
About the Life Sciences Industry
In 1982, Synthetic Insulin, produced by Eli Lilly and
Genentech. This was the first ever approved genetically
engineered human therapeutic.
Image: Wikipedia Commons
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
28
Drug Development: A Risky Endeavor
Discovery
Research
Lead
Optimization
of Drug
Candidates
Discovery Research
Millions of compounds
Preclinical
Studies
Bio/Chemical
Process
Development
IND
filing
Clinical Trials
Scale-Up /
Manufacturing
NDA
or
BLA
filing
FDA
review
Preclinical Studies Clinical Development and
Regulatory Affairs
71-2
1 in 10
About 15 years and > $1B!
Product
Launch!
Commercial
Operations
and Sales
Phase
IIIB/IV Trials
Career Paths in the Life Sciences
Photo: Wikipedia Commons
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
30
Career Ladder in Discovery Research for
Research Associates
SRA
SRA
SRA
SRA
Research
Associate
Student
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Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
31
Career Ladder in Discovery Research:
Ph.D.s are not technicians
CEO
VP R&D
VP Research or CSO
Fellow or
Principal
Scientist
Track
Director
Group Leader
Scientist I - III
Postdoc
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
32
Career Potential in Discovery Research
CEO
Consultant
Venture
Capital
Patent
Law
VP R&D
or CSO
Project
Management
Preclinical
Research
Regulatory or
Clinical Affairs
Quality
Discovery
Research
Academia
Other Areas:
Operations, Business
Development,
Marketing, Sales,
Tech Support,
Product Development
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
33
Going from Academia to Industry
Image: Wikipedia Commons
What you can do now to make
yourself more marketable
•
•
•
•
Human disease rather than basic research
Hot therapeutic areas of interest to industry
“Unmet medical needs”
Same techniques, drug screens, applied
science
• Patent your work
• Gain business understanding
• Gain understanding of clinical development
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
35
What you can do now -- continued
•
•
•
•
•
•
Collaborate with industry cohorts
Informational interviews
Industry postdoc
Follow biotech news
Publish, publish, publish (but don’t perish)
Presentations and attend conferences and
become a perceived expert (get visibility)
• Consider FAS, MSL, Tech Support, Trainer
• Attend industry events, network and start
early
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
36
Land a job on the business side
• Work at the OTTBD
• Visit Haas MBA program—management
consulting firms, career coaching
• Business classes
• Join a startup at QB3
• Entrepreneurial classes—CBE, QB3 series
• Entrepreneur chapter
• Talk to profs who consult or founders
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
37
What you can do now to land a job
on the business side--continued
• Follow the biotech stock
• Invest in public companies—demonstrate
financial acumen
• Show leadership—start something, run a
program, be a President
• Pubs not needed in business
• Read WSJ, follow biotech business news
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
38
Making the Leap to Industry
• Industry postdoc
• MBT programs, KGI, JHU, SJSU
• Keck Institute’s Postdoc Professional
Master’s Program (PPM)
• Certificates, classes @ UC Berkeley X and
UCSC X
• Additional degrees: MBA, MPH, JD
• Volunteer/intern
• Network
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
39
Jobs in Industry
Job search strategies
•
•
•
•
Looking for a job can be a full time job
Apply to jobs that interest you
Apply to jobs that will get you in the door
The more you interview, the more likely
you will find the most appealing job
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
41
Jobs in Industry
• Difficult job market--large numbers of
industry professionals seeking
employment
• Genentech Scientist I requirements
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
42
Build Your Network!
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
43
Why networking is so effective
• Someone that you know refers you to a
job opportunity
• The more people you know, the greater
your chances of being contacted or finding
out about an opportunity
• Personally-vouched for candidates
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
44
Local places to network
•
•
•
•
•
•
Local and national conferences
Local biopharma societies, trade associations
AWIS
WIB
ACRP
AAAS
• You name it, there is a society
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
45
Networking
www.careersbiotech.com
Photo from Wikipedia
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
46
The Art of Networking
• It’s a two-way street. Be helpful, ask
questions about the other person, ask
“what can I do for you?”
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
47
Networking No-No’s
• Can you get me a job?
• Are there any job openings in your
company? (what can you say instead?)
• Scanning the audience looking for other
people to talk to
• Ask a question and then walk away
• Looking desperate
• “I have to get a drink—I’ll be right back”
ditch
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
48
Using LinkedIn
• LinkedIn.com: recruiters use it
–
–
–
–
–
–
–
The greater your LinkedIn network, the more access you have
LinkIn with LIONs and power users
Join LinkedIn groups, alumni organizations
Include key words, therapeutic areas to interest recruiters
Email address or way to be contacted
Keep professional
Jobs are on site and groups
• MySpace, Facebook: set on private
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
49
Networking on the Internet
• Google “therapeutic area conference”
• Contact speakers, authors
• Search LinkedIn in specific companies that
interest you for people that you might
know
• Professors who consult/founders
• Contact alumni
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
50
“Shop” for a Job on the Internet
• Job posting sites
–
–
–
–
–
–
www.biospace.com
www.craigslist.org
www.audreysnetwork.com
www.careersbiotech.com
www.indeed.com
www.ventureloop.com
• Professional societies
– Therapeutic areas and functional areas, i.e.
immunology, neurosciences, oncology, marketing,
business development
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
51
Let the jobs find you
• Resume posting sites
–
–
–
–
–
–
www.biospace.com
www.indeed.com
www.medzilla.com
www.monster.com
www.execunet.com
www.bio2devicegroup.org
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
52
Career Fairs
• BioSpace, www.biospace.com
• Campus Career Fairs
• Society meetings, i.e. ASCB, AAAS,
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
53
Trade Shows at Scientific Conferences
•
•
•
•
BIO, www.bio.org the biggest
InformEx, Chemistry www.informex.com
ASCB, www.ascb.org
Interphex, manufacturing,
www.interphex.com
• Tri-Molecular, www.tri-conference.com
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
54
Career counselors and services
• On campus, medical schools, business,
law programs
• Alumni school counselors usually free
• Off campus
• www.edd.org, www.jvs.org,
www.thejobforum.org, NOVA, ProMatch,
Peninsula Works, EastBay Works, free
interview coaching and resume
preparation
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
55
Free Biotechnology News
•
BioSpace
–
–
•
BayBiotechReview
–
•
www.fiercebiotech.com
FierceBioResearch
–
•
www.baybiotechreview.com
FierceBiotech
–
•
www.biospace.com
Biospace careers insider
www.fiercebioresearcher.com
OnBioVC
–
www.onbiovc.com
•
The IN VIVO Blog
•
Nature Biotechnology
–
•
The Scientist
–
•
www.nature.com/nbt/
www.the-scientist.com
Biotechnology Industry Organization
–
www.bio.org
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
56
Resumes
Image: Wikipedia
Resumes: how to stand out
•
•
•
•
Prepare for the 5 second scan
Align skills with the position specs
Highlight and show how you fit the position
Add key words, therapeutic areas
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
58
Tips for submitting your resume to
large companies
•
•
•
•
Job requisition number
Career objective
Apply directly on the company’s website
Network, network, network!
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
59
Working with Recruiters
• They know about positions that may not
be posted on the Internet—the “hidden”
job market
• They will get your resume in front of the
hiring manager
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
60
Working with Recruiters
• Recruiters are paid by the company
• You are your own best job agent
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
61
Interviewing
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
62
The Art of Interviewing
• You’ve already pass the technical test—
corporate match
• Research the company
• Don’t interview like a postdoc!
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
63
Good Interviewing Books
• Knock em dead
• 101 Great Answers to the Toughest Interview
Questions
• 301 Smart Answers to Tough Interview
Questions
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
64
The Current Economy
The current economy: “The Times, They
are a Changin’”
•
•
•
•
2008 was a bad year
2009 was a *terrible* year
It’s a little better now
3 IPOs in 2009, 13 IPOs in 2010, 10 IPOs
in 2011, lackluster receptions
• Overall biotech sector was down
• Social media hot, 3.3% unemployment
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
66
Monster Report on Biotech Jobs 2011
• Job postings in biotech positive expansion 2011
• Hottest area: clinical lab techs and technicians
40%
• Areas hiring most (volume posting): Texas, NC,
Kentucky, Michigan, NJ, RH
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
67
In High Demand
•
•
•
•
•
•
Regulatory affairs
Sales
CLIA-certification
Bioreactors
QA and QC
Rare skills, i.e. ephiz
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
68
Where are the jobs?
• Academia
• Successful biopharmas
• Service companies, i.e. CROs and
CMOs
• Biofuels (bioreactors, fermentation,
microbiology, plant genetics (agbio))
• Small venture-backed companies
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
69
Top 5 lay-offs in 2011
•
•
•
•
•
•
Pfizer – 4,220
Novartis – 2,000
Abbott Labs – 1,900
AstraZeneca – 1,550
Sanofi – 700+
43,000 layoffs in big pharma in 2010
Source: www.fiercebiotech.com, December 9, 2011
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
70
Top 5 lay-offs in 2009
•
•
•
•
•
Pfizer/Wyeth – 19,500
Merck/Schering Plough – 16,000
J&J – 8,900
Astra Zeneca – 7,400
GlaxoSmithKline – 6,000
Source: www.fiercebiotech.com, December 9, 2009
www.careersbiotech.com
Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved.
71
Venture capital and capital markets
•
•
•
•
ROI for LS VCs was -1.5% in 2010
Less VCs, less money, smaller investments
Difficult for startups to raise money
Public markets less interested in LS, IPO
window lackluster
• VCs investing in later stage deals
• Corporate venture, academia-industry
partnerships
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M&As are bad for industry
• 30 mergers over last 60 years didn’t boost
productivity
• More companies = more successful drugs
• New areas of pharmacology most successful
• 25% fewer public biotechs in 2010 than 3 years
ago
Bernard Munos/Forbes 2011
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The FDA…
• Overburdened with added responsibilities
• Increasingly focused less on benefits and more
on possible risks
• Average review times increasing
• Regulatory environment raises “serious barriers
to innovation”
CHI Report, 2011
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Consequences of the FDA…
• Difficult to raise money—regulatory risks and
uncertainty
• Dramatic shift in clinical trials US to Europe
• Rise in number of drugs approved in EU first
• EU Docs learn new tech first
• Costs of RA and consultants going up
• Operations, experts move overseas
CHI Report, 2011
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The Scenario at Big Pharma…
• Dismal internal R&D returns
• Cost per successful drug has risen (cost
of R&D has gone up, shorter periods of
economic returns due to generics and
patent life span, declining productivity)
• Regulatory hurdles higher
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Big pharma solution: outsource R&D
to biotech
• “Externalize” small mol discovery research,
pre-Phase III compounds, particularly for
riskier therapeutic areas (NR, COPD, Cardio)
• Reduction in R&D research and reallocating
resources to in-license deals with biotechs
• Move from R&D to “Search & Development”
orgs
• Reduces investment risk
• Biotechs expected to become pharma’s main
R&D engine
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Reason for biopharma to outsource:
develop presence overseas
• Pursue a market presence
• China expected to be third largest Rx
market by 2013, number two in 2020
• Growing markets Australia, S. Korea,
India, Vietnam, Japan, Russia
• Cost of dev is 1/5 to 1/3rd, labor costs
are rapidly rising
• Serendipity lost
www.careersbiotech.com
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Outsourcing and impact on jobs
•
•
•
•
Chemistry and manufacturing overseas
Small molecule, devices, large mol safer
Clinical trials, preclinical, research and IT
Virtual companies= growth in services and
consultants
• Still need quality and PM
• Global leadership
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Not so bad off…
• Biotech and medical devices better than
other industries
• Big biotech is doing well
• Big pharma is cash rich, patents expiring,
need to fill pipelines
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VCs are Funding Biotech and Medical
Device Companies
Source: PricewaterhouseCoopers, Money Tree Report, www.pwcmoneytree.com
Northwest Funding
Source: PricewaterhouseCoopers, Money Tree Report, www.pwcmoneytree.com
History of VC Funding in Biotech
Source: PricewaterhouseCoopers, Money Tree Report, www.pwcmoneytree.com
Hot growth potential sectors: new and
emerging areas
• Healthcare, surgery centers
• Generics and biosimilars
• Biofuels and green/clean tech, grey water,
energy
• Personalized medicine/companion Dx
• Combination therapies
• HC IT, telemedicine, mobile HC apps, “doc-inthe-box”
www.careersbiotech.com
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Trend to transition to electronic data
capture in just about every job function
• Healthcare informatics (i.e. electronic health
records)
• Laboratory automation
• Bioinformatics (personalized medicine)
• Data management, bio-IT
• Regulatory affairs, i.e. electronic filing
• Discovery research, i.e. eNotebooks
• Intersection of life and computer sciences
training
www.careersbiotech.com
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The Future of the Life Sciences Remains
Promising
• Significant unmet medical needs remain—
neurological disorders, cancer, infectious
diseases, diabetes, obesity,
cardiovascular diseases
• People are living longer, aging population
all over the world
• Tremendous market opportunity in China,
India and other emerging countries
• Energy
www.careersbiotech.com
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Recommendations for job search during
difficult economic times
• Non-glamorous jobs
• Temp-to-hire/contract ops
• Safety in biotech hubs: SF, SD, Boston,
Seattle
• Good time to start a company
• Start networking early
www.careersbiotech.com
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Conclusions
• Over >100 different careers in academia,
industry and government
• Many different industries in which to work
• Find the vocation that best suits your
interests, skills and goals
• Do what you love
• Not money or a fad
• Be flexible about job search--your first job
will not be your last
Find your niche
Recommended Academia Career Books
• At the Bench and At the Helm, Kathy Barker,
CSHLP
• Advice for New Faculty Members, Robert Boice
• Making the Right Moves: A Practical Guide to
Scientific Management for Postdocs and New
Faculty, Burroughs Wellcome Fund, HHMI,
www.hhmi.org/labmanagement
• Lab Dynamics: Management Skills for Scientists,
Carl and Suzanne Cohen, CSHLP
• Managing Scientists, Alice Sapienza
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Recommended Industry Books
• Science Lessons, Gordon Binder, Former CEO
of Amgen
• Emperor of All Maladies, Siddhartha Mukherjee
• Put Your Science to Work, Peter Fiske
• Career Opportunities in Clinical Drug Research,
Rebecca Anderson
• Nontraditional Careers for Chemists, Lisa Balbes
• Alternative Careers in Science, Cynthia
Robbins-Roth
www.careersbiotech.com
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Book Information
• Careers in Biotechnology and Drug Development
• Published by Cold Spring Harbor Laboratory Press
•
•
•
•
Books available on Amazon and www.cshlpress.org
Paperbacks selling for $35
Hard covers selling for $47
Available in German
• www.careersbiotech.com
www.careersbiotech.com
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Additional Information
• Free sample chapter on Careers in Project
Management, www.careersbiotech.com
• List of job posting sites under career
resources at www.careersbiotech.com
www.careersbiotech.com
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Contact Information
Toby Freedman, Ph.D.
President, Synapsis Search
Recruiting in the life sciences:
Biotechnology, Biofuels, Services, NonProfits
www.synapsissearch.com
[email protected]
www.careersbiotech.com
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Acknowledgments
• Over 200+ industry professionals
Special Thanks to:
• Molly Schmid, Joseph Carlino, Betsy Alberty,
Angelie Agarwal, Bill Lindstaedt
Even More Special Thanks to:
• My father, Bill Freedman, who edited the
chapters multiple times and Peter Symonds
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Thank you!
Start companies, be successful,
and find a cure for cancer!
www.careersbiotech.com
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So Many Careers To Choose!
www.careersbiotech.com
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