Transcript spore-canada

Introduction to the
Knowledge Discovery Department
Institute for Infocomm Research
Limsoon Wong
Deputy Executive Director (Research)
I2R: Imagination to reality
I2R
•
BMRC
SERC
IMRE
IME
•
DSI
IHPC
ICES
SIMTECH
•
Advance
Infocomm Technology
to benefit humanity and
create prosperity for
S’pore
core values: Dedication to
excellence, passion for
innovation, integrity &
respect
size: 350 RSEs
mission:
EDB-iDA ICT Cluster Map
Organization
I 2R
Services & Applications
Infocomm
Security
• Cryptography
• Network security
• Information
security
Communications & Devices
Knowledge
Discovery
E-Service
Infrastructure
• Knowledge
Extraction
• Decision Systems
• Discovery
Systems
• Service
Composition
• Service creation
• Data-in-Network
• Connected Home
• Secure Filesystem/
DBMS
Embedded
Systems
Radio Systems
• Terminal
• Software Defined
Radio
• Transceiver system
• Antenna
• Radio Over Fiber
• UWB
Media
Media
Processing
• Mutimedia Signal
Processing
• Noise Reduction
Networking
• Next Gen IP
• End-to-end QoS
• Mobile Middleware
• Mobile Adhoc Networks
• Mobile Sensor Networks
Media
Semantics
Human Computer
Interaction
• Media Adaptation
• Mixed Media Mining
• Natural Language
Synergy
• Pervasive Media
Digital Wireless
• Modem Technology
• Multiple Access
• Smart Antenna Array
Systems
• Perceptual Human
Media
• Speech & Dialogue
• Biometrics
Lightwave
• Network Design
• WDM Systems
• Fibre Technology
Services & Applications
Information
Security
Cryptography
Cryptographic techniques for
privacy protection, highspeed encryption, group
digital signatures and new
public key infrastructure
Information Security
Techniques for privacy
protection, peer-to-peer
system security and media
security
Knowledge
Discovery
Knowledge Extraction
Service Creation
Data fusion from sensors,
knowledge extraction
technologies. Applications in
functional genomics & gene
regulatory networks
Policy-based framework for
creating/managing
application, storage and
network services
Data-in-Network
Decision Systems
Data Mining technologies.
Applications in clinical data
analysis and protein network
analysis
Discovery Systems
Network Security
Wireless network security,
intrusion detection and
technology to trace attackers
E-services
Infrastructure
Data cleansing, modeling &
knowledge management
technologies. Applications in
immunoinformatics and
venominformatics
High-speed data cache and
IPC on optical network
Service Composition
Tech for consumers to
create personalized
services from component eservices
Connected Home
Reference design for an
OSGi compliant residential
gateway
Secure Filesystem
Steganographic and reliable
file systems/DBMSs on
externally managed
platforms
History
8 years of
bioinformatics
R&D in
Singapore
Integration
Technology
(Kleisli)
MHC-Peptide Protein Interactions
Extraction (PIES)
Binding
(PREDICT)
Gene Expression
Molecular
Cleansing &
Connections & Medical Record
Warehousing
Datamining (PCL)
(FIMM)
Gene Feature
Recognition (Dragon)
Venom
Informatics
GeneticXchange
1994
ISS
1996
1998
KRDL
2000
Biobase
2002
LIT/I2R
Directions
Knowledge Extraction
• gene regulatory network
• endocrinology info system
Translate inspiration from
biological systems into
advancement in life and
computing sciences
Discovery Systems
• immunoinformatics
• venominformatics
Advance data mining
technologies in decision
systems for complex
problems
Technologies for
• data mining
• data fusion
• data cleansing
• data modeling
• knowledge extraction
• knowledge management
Decision Systems
• clinical data analysis
• protein interaction
network
Decision Systems Lab Highlight
PCL Technology
• Machine learning of
emerging patterns
• Rules learned by
computers easily
understood by
doctors
• High accuracy
Yeoh et al.
Cancer Cell 1, 133-143, 2002
Discovery Systems Lab Highlight
FANTOM2 Consortium
Nature 420, 563-573, 2002
• Brusic et al. Cytokinerelated genes identified from the RIKEN
full-length mouse
cDNA dataset.
Genome Res. (in press)
• Silva et al. Identification of novel human
disease-related gene
candidates from the
RIKEN full-length
mouse cDNA dataset.
Genome Res. (in press)
KE Lab Highlight
• Dragon Promoter
Finder and Dragon
Gene Start Finder
• Very high accuracy,
order of magnitude
improvement
• Licensed to
Biobase, integrated
with
TRANSPLORER
and TRANSFAC
Qualification
• 18 full-time staff (9 PhD, 6MSc, and 3
BSc) and 10-20 students at any time
• Our faculty holds adjunct professorial
positions (SANBI, Univ. of Canberra,
NUS, and NTU)
• During the last two years 8 MSc
students graduated under our
supervision
Professional Activities
•
•
3 chief editorial roles, and 9
editorial board memberships
International Conferences (last 5 years): 4 conference chairs,
and more than 40 program committee
roles, 10 keynote lectures, and dozens
of plenary talks
Journals:
Track Record
•
•
•
More than 100 in last 5
years, many in top journals (e.g. Nature,
PNAS, Cancer Cell, JACM) and top
conferences.
Patents (last 5 years): 1 granted and 6 pending
Commercialization (last 5 years): 2 international start-ups
and one software licensed
Publications (last 5 years):
People
Decision Systems
Head:
Dr. See-Kiong Ng
PI:
A/Prof. Limsoon Wong, Dr. Jinyan Li
Staff:
Huiqing Liu, Zhuo Zhang, Soon-Heng Tan
Post Doc:
Dr. Shaowu Meng
Discovery Systems
Head:
A/Prof. Vladimir Brusic
Staff:
Judice Koh, Guanglan Zhang, Seng Hong Seah
Post Doc:
Dr. Rekha Pillai
Knowledge Extraction
Head:
Prof. Vladimir B. Bajic
Staff:
Hao Han, SPT Krishnan, Allen Chong, Sin Lam Tan
Post Doc:
Dr. Suisheng Tang
Here they are...